Transcriptional programming of normal and inflamed human epidermis at single-cell resolution JB Cheng, AJ Sedgewick, AI Finnegan, P Harirchian, J Lee, S Kwon, ... Cell reports 25 (4), 871-883, 2018 | 261 | 2018 |
Learning mixed graphical models with separate sparsity parameters and stability-based model selection AJ Sedgewick, I Shi, RM Donovan, PV Benos BMC bioinformatics 17, 307-318, 2016 | 94 | 2016 |
Mixed graphical models for integrative causal analysis with application to chronic lung disease diagnosis and prognosis AJ Sedgewick, K Buschur, I Shi, JD Ramsey, VK Raghu, DV Manatakis, ... Bioinformatics 35 (7), 1204-1212, 2019 | 73 | 2019 |
Efficient stochastic simulation of chemical kinetics networks using a weighted ensemble of trajectories RM Donovan, AJ Sedgewick, JR Faeder, DM Zuckerman The Journal of chemical physics 139 (11), 2013 | 65 | 2013 |
Single-cell profiling reveals divergent, globally patterned immune responses in murine skin inflammation Y Liu, C Cook, AJ Sedgewick, S Zhang, MS Fassett, ... Iscience 23 (10), 2020 | 47 | 2020 |
Learning subgroup-specific regulatory interactions and regulator independence with PARADIGM AJ Sedgewick, SC Benz, S Rabizadeh, P Soon-Shiong, CJ Vaske Bioinformatics 29 (13), i62-i70, 2013 | 45 | 2013 |
Validation of genomic and transcriptomic models of homologous recombination deficiency in a real-world pan-cancer cohort BD Leibowitz, BV Dougherty, JSK Bell, J Kapilivsky, J Michuda, ... BMC cancer 22 (1), 587, 2022 | 39 | 2022 |
Large scale, robust, and accurate whole transcriptome profiling from clinical formalin-fixed paraffin-embedded samples Y Newton, AJ Sedgewick, L Cisneros, J Golovato, M Johnson, CW Szeto, ... Scientific reports 10 (1), 17597, 2020 | 32 | 2020 |
PARP1 rs1805407 increases sensitivity to PARP1 inhibitors in cancer cells suggesting an improved therapeutic strategy I Abecassis, AJ Sedgewick, M Romkes, S Buch, T Nukui, MG Kapetanaki, ... Scientific reports 9 (1), 3309, 2019 | 32 | 2019 |
Data-independent acquisition mass spectrometry to quantify protein levels in FFPE tumor biopsies for molecular diagnostics YJ Kim, SMM Sweet, JD Egertson, AJ Sedgewick, S Woo, W Liao, ... Journal of proteome research 18 (1), 426-435, 2018 | 29 | 2018 |
A single-cell transcriptional gradient in human cutaneous memory T cells restricts Th17/Tc17 identity CP Cook, M Taylor, Y Liu, R Schmidt, A Sedgewick, E Kim, A Hailer, ... Cell Reports Medicine 3 (8), 2022 | 19 | 2022 |
Regional molecular signature of the symptomatic atherosclerotic carotid plaque EM Caparosa, AJ Sedgewick, G Zenonos, Y Zhao, DL Carlisle, ... Neurosurgery 85 (2), E284-E293, 2019 | 19 | 2019 |
A20 and ABIN1 suppression of a keratinocyte inflammatory program with a shared single-cell expression signature in diverse human rashes P Harirchian, J Lee, S Hilz, AJ Sedgewick, BEP White, MJ Kesling, T Mully, ... Journal of Investigative Dermatology 139 (6), 1264-1273, 2019 | 19 | 2019 |
Mixed graphical models for causal analysis of multi-modal variables AJ Sedgewick, JD Ramsey, P Spirtes, C Glymour, PV Benos arXiv preprint arXiv:1704.02621, 2017 | 15 | 2017 |
Investigating tumoral and temporal heterogeneity through comprehensive-omics profiling in patients with metastatic triple negative breast cancer. C Szeto, R Parulkar, AJ Sedgewick, SC Benz, F Cecchi, TA Hembrough, ... Journal of Clinical Oncology 35 (15_suppl), 1093-1093, 2017 | 4 | 2017 |
Graphical models for de novo and pathway-based network prediction over multi-modal high-throughput biological data AJ Sedgewick University of Pittsburgh, 2016 | 4 | 2016 |
Potential drug targets for adenoid cystic carcinoma elucidated by proteogenomic analysis SP Thyparambil, YJ Kim, AG Chambers, D Yan, S Sellappan, ... Cancer Research 78 (13_Supplement), 778-778, 2018 | 2 | 2018 |
Comprehensive proteomic and genomic profiling to identify therapeutic targets in adenoid cystic carcinoma. SP Thyparambil, YJ Kim, A Chambers, D Yan, S Sellappan, C Gong, ... Journal of Clinical Oncology 36 (15_suppl), 6053-6053, 2018 | 2 | 2018 |
A Genomic Analysis of Esophageal Squamous Cell Carcinoma in Eastern Africa K Van Loon, EJ Mmbaga, BP Mushi, M Selekwa, A Mwanga, LO Akoko, ... Cancer Epidemiology, Biomarkers & Prevention 32 (10), 1411-1420, 2023 | 1 | 2023 |
Longitudinal Transcriptome Analysis of Myelodysplatic Syndrome Progression to Acute Myeloid Leukemia: Implications for Prognosis E De Clara, AM Ali, J Kayani, C Szeto, J Golovato, A Sedgewick, JG Jurcic, ... Blood 130, 3961, 2017 | 1 | 2017 |