Thomas P. Sakmar
Thomas P. Sakmar
Richard M. & Isabel P. Furlaud Professor, Rockefeller University
E-mailová adresa ověřena na: rockefeller.edu - Domovská stránka
Název
Citace
Citace
Rok
Defeating Alzheimer's disease and other dementias: a priority for European science and society
B Winblad, P Amouyel, S Andrieu, C Ballard, C Brayne, H Brodaty, ...
The Lancet Neurology 15 (5), 455-532, 2016
12452016
AMD3100, a small molecule inhibitor of HIV-1 entry via the CXCR4 co-receptor
GA Donzella, D Schols, SW Lin, JA Esté, KA Nagashima, PJ Maddon, ...
Nature medicine 4 (1), 72-77, 1998
9331998
Glutamic acid-113 serves as the retinylidene Schiff base counterion in bovine rhodopsin
TP Sakmar, RR Franke, HG Khorana
Proceedings of the National Academy of Sciences 86 (21), 8309-8313, 1989
8101989
A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5
T Dragic, A Trkola, DAD Thompson, EG Cormier, FA Kajumo, E Maxwell, ...
Proceedings of the National Academy of Sciences 97 (10), 5639-5644, 2000
5942000
Cysteine residues 110 and 187 are essential for the formation of correct structure in bovine rhodopsin
SS Karnik, TP Sakmar, HB Chen, HG Khorana
Proceedings of the National Academy of Sciences 85 (22), 8459-8463, 1988
5211988
Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F
SP Sheikh, TA Zvyaga, O Lichtarge, TP Sakmar, HR Bourne
nature 383 (6598), 347-350, 1996
4851996
Rhodopsin mutants that bind but fail to activate transducin
RR Franke, B Konig, TP Sakmar, HG Khorana, KP Hofmann
Science 250 (4977), 123-125, 1990
4241990
Update on Alzheimer's disease therapy and prevention strategies
WV Graham, A Bonito-Oliva, TP Sakmar
Annual review of medicine 68, 413-430, 2017
3792017
Rhodopsin: structural basis of molecular physiology
ST Menon, M Han, TP Sakmar
Physiological reviews 81 (4), 1659-1688, 2001
3792001
CXCR7/CXCR4 heterodimer constitutively recruits β-arrestin to enhance cell migration
FM Décaillot, MA Kazmi, Y Lin, S Ray-Saha, TP Sakmar, P Sachdev
Journal of Biological Chemistry 286 (37), 32188-32197, 2011
3342011
G protein-coupled receptors self-assemble in dynamics simulations of model bilayers
X Periole, T Huber, SJ Marrink, TP Sakmar
Journal of the American Chemical Society 129 (33), 10126-10132, 2007
3322007
Structure and function in rhodopsin. Studies of the interaction between the rhodopsin cytoplasmic domain and transducin.
RR Franke, TP Sakmar, RM Graham, HG Khorana
Journal of Biological Chemistry 267 (21), 14767-14774, 1992
3231992
Amino-terminal substitutions in the CCR5 coreceptor impair gp120 binding and human immunodeficiency virus type 1 entry
T Dragic, A Trkola, SW Lin, KA Nagashima, F Kajumo, L Zhao, WC Olson, ...
Journal of virology 72 (1), 279-285, 1998
3081998
Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12
CT Veldkamp, C Seibert, FC Peterson, NB De la Cruz, JC Haugner III, ...
Science signaling 1 (37), ra4-ra4, 2008
3062008
Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12
CT Veldkamp, C Seibert, FC Peterson, NB De la Cruz, JC Haugner III, ...
Science signaling 1 (37), ra4-ra4, 2008
3062008
Protonation states of membrane-embedded carboxylic acid groups in rhodopsin and metarhodopsin II: a Fourier-transform infrared spectroscopy study of site-directed mutants
K Fahmy, F Jäger, M Beck, TA Zvyaga, TP Sakmar, F Siebert
Proceedings of the National Academy of Sciences 90 (21), 10206-10210, 1993
3001993
Analysis of the mechanism by which the small-molecule CCR5 antagonists SCH-351125 and SCH-350581 inhibit human immunodeficiency virus type 1 entry
F Tsamis, S Gavrilov, F Kajumo, C Seibert, S Kuhmann, T Ketas, A Trkola, ...
Journal of virology 77 (9), 5201-5208, 2003
2942003
Curvature and hydrophobic forces drive oligomerization and modulate activity of rhodopsin in membranes
AV Botelho, T Huber, TP Sakmar, MF Brown
Biophysical journal 91 (12), 4464-4477, 2006
2922006
Specific tryptophan UV-absorbance changes are probes of the transition of rhodopsin to its active state
SW Lin, TP Sakmar
Biochemistry 35 (34), 11149-11159, 1996
2871996
A single amino acid substitution in rhodopsin (lysine 248—-leucine) prevents activation of transducin.
RR Franke, TP Sakmar, DD Oprian, HG Khorana
Journal of Biological Chemistry 263 (5), 2119-2122, 1988
2821988
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Články 1–20