David W Scott
David W Scott
Clinician-Scientist, BC Cancer; Associate Professor, Department of Medicine, University of British
Verified email at
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Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma
RD Morin, M Mendez-Lago, AJ Mungall, R Goya, KL Mungall, RD Corbett, ...
Nature 476 (7360), 298-303, 2011
Concurrent expression of MYC and BCL2 in diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone
NA Johnson, GW Slack, KJ Savage, JM Connors, S Ben-Neriah, S Rogic, ...
Journal of clinical oncology 30 (28), 3452, 2012
EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation
W Béguelin, R Popovic, M Teater, Y Jiang, KL Bunting, M Rosen, H Shen, ...
Cancer cell 23 (5), 677-692, 2013
A probabilistic classification tool for genetic subtypes of diffuse large B cell lymphoma with therapeutic implications
GW Wright, JD Phelan, ZA Coulibaly, S Roulland, RM Young, JQ Wang, ...
Cancer cell 37 (4), 551-568. e14, 2020
Determining cell-of-origin subtypes of diffuse large B-cell lymphoma using gene expression in formalin-fixed paraffin-embedded tissue
DW Scott, GW Wright, PM Williams, CJ Lih, W Walsh, ES Jaffe, ...
Blood, The Journal of the American Society of Hematology 123 (8), 1214-1217, 2014
The tumour microenvironment in B cell lymphomas
DW Scott, RD Gascoyne
Nature Reviews Cancer 14 (8), 517-534, 2014
The international consensus classification of mature lymphoid neoplasms: a report from the clinical advisory committee
E Campo, ES Jaffe, JR Cook, L Quintanilla-Martinez, SH Swerdlow, ...
Blood, The Journal of the American Society of Hematology 140 (11), 1229-1253, 2022
Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing
RD Morin, K Mungall, E Pleasance, AJ Mungall, R Goya, RD Huff, ...
Blood, The Journal of the American Society of Hematology 122 (7), 1256-1265, 2013
Prognostic significance of diffuse large B-cell lymphoma cell of origin determined by digital gene expression in formalin-fixed paraffin-embedded tissue biopsies
DW Scott, A Mottok, D Ennishi, GW Wright, P Farinha, S Ben-Neriah, ...
Journal of clinical oncology 33 (26), 2848, 2015
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development
A Ortega-Molina, IW Boss, A Canela, H Pan, Y Jiang, C Zhao, M Jiang, ...
Nature medicine 21 (10), 1199-1208, 2015
CNS international prognostic index: a risk model for CNS relapse in patients with diffuse large B-cell lymphoma treated with R-CHOP
N Schmitz, S Zeynalova, M Nickelsen, R Kansara, D Villa, LH Sehn, ...
Journal of Clinical Oncology 34 (26), 3150-3156, 2016
Genomic rearrangements involving programmed death ligands are recurrent in primary mediastinal large B-cell lymphoma
DDW Twa, FC Chan, S Ben-Neriah, BW Woolcock, A Mottok, KL Tan, ...
Blood, The Journal of the American Society of Hematology 123 (13), 2062-2065, 2014
Double-hit gene expression signature defines a distinct subgroup of germinal center B-cell-like diffuse large B-cell lymphoma
D Ennishi, A Jiang, M Boyle, B Collinge, BM Grande, S Ben-Neriah, ...
Journal of Clinical Oncology 37 (3), 190, 2019
Impact of concordant and discordant bone marrow involvement on outcome in diffuse large B-cell lymphoma treated with R-CHOP
LH Sehn, DW Scott, M Chhanabhai, B Berry, A Ruskova, L Berkahn, ...
J clin oncol 29 (11), 1452-1457, 2011
Loss of BAF250a (ARID1A) is frequent in high‐grade endometrial carcinomas
KC Wiegand, AF Lee, OM Al‐Agha, C Chow, SE Kalloger, DW Scott, ...
The Journal of pathology 224 (3), 328-333, 2011
Tumor-associated macrophages predict inferior outcomes in classic Hodgkin lymphoma: a correlative study from the E2496 Intergroup trial
KL Tan, DW Scott, F Hong, BS Kahl, RI Fisher, NL Bartlett, RH Advani, ...
Blood, The Journal of the American Society of Hematology 120 (16), 3280-3287, 2012
CREBBP Inactivation Promotes the Development of HDAC3-Dependent Lymphomas
Y Jiang, A Ortega-Molina, H Geng, HY Ying, K Hatzi, S Parsa, D McNally, ...
Cancer discovery 7 (1), 38-53, 2017
Molecular and genetic characterization of MHC deficiency identifies EZH2 as therapeutic target for enhancing immune recognition
D Ennishi, K Takata, W Béguelin, G Duns, A Mottok, P Farinha, ...
Cancer discovery 9 (4), 546-563, 2019
Clinical Impact of the Cell-of-Origin Classification and the MYC/BCL2 Dual Expresser Status in Diffuse Large B-Cell Lymphoma Treated Within Prospective Clinical …
AM Staiger, M Ziepert, H Horn, DW Scott, TFE Barth, HW Bernd, AC Feller, ...
Journal of clinical oncology 35 (22), 2515-2526, 2017
Histological transformation and progression in follicular lymphoma: a clonal evolution study
R Kridel, FC Chan, A Mottok, M Boyle, P Farinha, K Tan, B Meissner, ...
PLoS medicine 13 (12), e1002197, 2016
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