| The role of protein-protein and protein-membrane interactions on P450 function EE Scott, CR Wolf, M Otyepka, SC Humphreys, JR Reed, CJ Henderson, ... Drug Metabolism and Disposition 44 (4), 576-590, 2016 | 32 | 2016 |
| The two faces of aldehyde oxidase: oxidative and reductive transformations of 5-nitroquinoline EM Paragas, SC Humphreys, J Min, CA Joswig-Jones, JP Jones Biochemical pharmacology 145, 210-217, 2017 | 21 | 2017 |
| Tracking individual membrane proteins and their biochemistry: The power of direct observation AO Barden, AS Goler, SC Humphreys, S Tabatabaei, M Lochner, ... Neuropharmacology 98, 22-30, 2015 | 18 | 2015 |
| Quantification of siRNA-antibody conjugates in biological matrices by triplex-forming oligonucleotide ELISA SC Humphreys, MB Thayer, IDG Campuzano, C Netirojjanakul, BM Rock nucleic acid therapeutics 29 (3), 161-166, 2019 | 9 | 2019 |
| ecoAO: a simple system for the study of human aldehyde oxidases role in drug metabolism EM Paragas, SC Humphreys, J Min, CA Joswig-Jones, S Leimkühler, ... ACS omega 2 (8), 4820-4827, 2017 | 9 | 2017 |
| Plasma and Liver Protein Binding of N-Acetylgalactosamine–Conjugated Small Interfering RNA SC Humphreys, MB Thayer, JM Lade, B Wu, K Sham, B Basiri, Y Hao, ... Drug Metabolism and Disposition 47 (10), 1174-1182, 2019 | 8 | 2019 |
| Substrate Dependent Native Luminescence from Cytochromes P450 3A4, 2C9, and P450cam C Barnaba, SC Humphreys, AO Barden, JP Jones, JA Brozik The Journal of Physical Chemistry B 120 (12), 3038-3047, 2016 | 8 | 2016 |
| Emerging siRNA design principles and consequences for biotransformation and disposition in drug development SC Humphreys, MB Thayer, J Campbell, WLK Chen, D Adams, JM Lade, ... Journal of Medicinal Chemistry 63 (12), 6407-6422, 2020 | 6 | 2020 |
| POE Immunoassay: Plate-based oligonucleotide electro-chemiluminescent immunoassay for the quantification of nucleic acids in biological matrices MB Thayer, SC Humphreys, KS Chung, JM Lade, KD Cook, BM Rock Scientific reports 10 (1), 1-9, 2020 | 4 | 2020 |
| Prolonged cultured human hepatocytes as an in vitro experimental system for the evaluation of potency and duration of activity of RNA therapeutics: Demonstration of prolonged … Q Yang, SC Humphreys, JM Lade, AP Li Biochemical Pharmacology 189, 114374, 2021 | 3 | 2021 |
| Introducing an In Vitro Liver Stability Assay Capable of Predicting the In Vivo Pharmacodynamic Efficacy of siRNAs for IVIVC B Basiri, F Xie, B Wu, SC Humphreys, JM Lade, MB Thayer, P Yamaguchi, ... Molecular Therapy-Nucleic Acids 21, 725-736, 2020 | 3 | 2020 |
| Case Study 12: Roadmap to Quantifying Ago2-Mediated siRNA Metabolic Activation Kinetics SC Humphreys, B Basiri, A Abbasi, BM Rock Enzyme Kinetics in Drug Metabolism, 825-841, 2021 | | 2021 |
| Half-life extension of peptidic APJ agonists by N-terminal lipid conjugation AB Reed, BA Lanman, JR Holder, BH Yang, J Ma, SC Humphreys, ... Bioorganic & Medicinal Chemistry Letters 30 (21), 127499, 2020 | | 2020 |
| An In Vitro Human Hepatocyte Assay for the Evaluation of the Efficacy of GalNac-Conjugated siRNA Q Yang, S Humphreys, J Lade, A Li MOLECULAR THERAPY 28 (4), 111-111, 2020 | | 2020 |
| Detection assay for protein-polynucleotide conjugates M Thayer, S Humphreys US Patent App. 16/434,056, 2019 | | 2019 |
| ecoAO: A Simple System for the Study of Drug Metabolism by Human Aldehyde Oxidase EM Paragas, S Humphreys, J Min, C Joswig‐Jones, J Jones The FASEB Journal 31, 669.15-669.15, 2017 | | 2017 |
| Non‐transporter mediated drug permeability across MDCK cell monolayers: Towards an explicit definition of the partition constant for passive drug interactions with cell membranes S Humphreys The FASEB Journal 30, lb547-lb547, 2016 | | 2016 |
| Deconvoluting the dance of the cytochrome P450 metabolon at the lipid bilayer SC Humphreys Washington State University, 2016 | | 2016 |
| Deconvoluting the Dance: Cytochrome P450 Interaction Mapping via Super‐Resolution Imaging S Humphreys, A Barden, C Barnaba, J Brozik, J Jones The FASEB Journal 29, 778.2, 2015 | | 2015 |
| Super-resolution imaging and reaction mapping of P450 3A4 and P450 reductase in heterogeneous biomimetics: Starry night JA Brozik, SC Humphreys, C Barnaba, AO Barden, JP Jones Biophysical Journal 108 (2), 250a, 2015 | | 2015 |
