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Simon Wisnovsky
Simon Wisnovsky
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Cited by
Cited by
Year
Lysosome-targeting chimaeras for degradation of extracellular proteins
SM Banik, K Pedram, S Wisnovsky, G Ahn, NM Riley, CR Bertozzi
Nature 584 (7820), 291-297, 2020
6042020
Targeting mitochondrial DNA with a platinum-based anticancer agent
SP Wisnovsky, JJ Wilson, RJ Radford, MP Pereira, MR Chan, RR Laposa, ...
Chemistry & biology 20 (11), 1323-1328, 2013
2222013
Peptide-mediated delivery of chemical probes and therapeutics to mitochondria
SR Jean, M Ahmed, EK Lei, SP Wisnovsky, SO Kelley
Accounts of chemical research 49 (9), 1893-1902, 2016
2072016
Molecular vehicles for mitochondrial chemical biology and drug delivery
S Rin Jean, DV Tulumello, SP Wisnovsky, EK Lei, MP Pereira, SO Kelley
ACS chemical biology 9 (2), 323-333, 2014
1442014
Mitochondrial DNA repair and replication proteins revealed by targeted chemical probes
S Wisnovsky, SR Jean, S Liyanage, A Schimmer, SO Kelley
Nature chemical biology 12 (7), 567-573, 2016
1022016
Mitochondrial chemical biology: new probes elucidate the secrets of the powerhouse of the cell
S Wisnovsky, EK Lei, SR Jean, SO Kelley
Cell chemical biology 23 (8), 917-927, 2016
932016
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
S Wisnovsky, L MŲckl, SA Malaker, K Pedram, GT Hess, NM Riley, ...
Proceedings of the National Academy of Sciences 118 (5), e2015024118, 2021
912021
Bump-and-hole engineering identifies specific substrates of glycosyltransferases in living cells
B Schumann, SA Malaker, SP Wisnovsky, MF Debets, AJ Agbay, ...
Molecular cell 78 (5), 824-834. e15, 2020
832020
Metabolic precision labeling enables selective probing of O-linked N-acetylgalactosamine glycosylation
MF Debets, OY Tastan, SP Wisnovsky, SA Malaker, N Angelis, ...
Proceedings of the National Academy of Sciences 117 (41), 25293-25301, 2020
562020
Re-directing an alkylating agent to mitochondria alters drug target and cell death mechanism
R Mourtada, SB Fonseca, SP Wisnovsky, MP Pereira, X Wang, R Hurren, ...
PloS one 8 (4), e60253, 2013
422013
DNA polymerase θ increases mutational rates in mitochondrial DNA
S Wisnovsky, T Sack, DJ Pagliarini, RR Laposa, SO Kelley
ACS chemical biology 13 (4), 900-908, 2018
312018
Mitochondria-penetrating peptides conjugated to desferrioxamine as chelators for mitochondrial labile iron
RYP Alta, HA Vitorino, D Goswami, CW Liria, SP Wisnovsky, SO Kelley, ...
PloS one 12 (2), e0171729, 2017
292017
Design of a mucin-selective protease for targeted degradation of cancer-associated mucins
K Pedram, DJ Shon, GS Tender, NR Mantuano, JJ Northey, KJ Metcalf, ...
Nature biotechnology 42 (4), 597-607, 2024
282024
Lysosome targeting chimeras (LYTACs) for the degradation of secreted and membrane proteins
S Banik, K Pedram, S Wisnovsky, N Riley, C Bertozzi
282019
Reading the glyco-code: New approaches to studying protein–carbohydrate interactions
S Wisnovsky, CR Bertozzi
Current opinion in structural biology 75, 102395, 2022
262022
Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth
E Scott, K Hodgson, B Calle, H Turner, K Cheung, A Bermudez, ...
Oncogene 42 (12), 926-937, 2023
202023
MYC-driven synthesis of Siglec ligands is a glycoimmune checkpoint
BAH Smith, A Deutzmann, KM Correa, CS Delaveris, R Dhanasekaran, ...
Proceedings of the National Academy of Sciences 120 (11), e2215376120, 2023
202023
The 5′ binding MID domain of human Argonaute2 tolerates chemically modified nucleotide analogues
GF Deleavey, F Frank, M Hassler, S Wisnovsky, B Nagar, MJ Damha
Nucleic acid therapeutics 23 (1), 81-87, 2013
172013
Elucidating the cellular determinants of targeted membrane protein degradation by lysosome-targeting chimeras
G Ahn, NM Riley, RA Kamber, S Wisnovsky, S Moncayo von Hase, ...
Science 382 (6668), eadf6249, 2023
152023
Characterization of Trypanosoma cruzi MutY DNA glycosylase ortholog and its role in oxidative stress response
M Kunrath-Lima, BM RepolÍs, CL Alves, C Furtado, MA Raj„o, ...
Infection, Genetics and Evolution 55, 332-342, 2017
92017
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