| Drug discovery using chemical systems biology: repositioning the safe medicine Comtan to treat multi-drug and extensively drug resistant tuberculosis SL Kinnings, N Liu, N Buchmeier, PJ Tonge, L Xie, PE Bourne PLoS computational biology 5 (7), e1000423, 2009 | 381 | 2009 |
| A machine learning-based method to improve docking scoring functions and its application to drug repurposing SL Kinnings, N Liu, PJ Tonge, RM Jackson, L Xie, PE Bourne Journal of chemical information and modeling 51 (2), 408-419, 2011 | 234 | 2011 |
| Factors affecting levels of circulating cell‐free fetal DNA in maternal plasma and their implications for noninvasive prenatal testing SL Kinnings, JA Geis, E Almasri, H Wang, X Guan, RM McCullough, ... Prenatal Diagnosis 35 (8), 816-822, 2015 | 222 | 2015 |
| Novel Computational Approaches to Polypharmacology as a Means to Define Responses to Individual Drugs PE Bourne, L Xie, L Xie Annual Review of Pharmacology and Toxicology 52 (1), 2011 | 221 | 2011 |
| Rare autosomal trisomies, revealed by maternal plasma DNA sequencing, suggest increased risk of feto-placental disease MD Pertile, M Halks-Miller, N Flowers, C Barbacioru, SL Kinnings, ... Science translational medicine 9 (405), eaan1240, 2017 | 164 | 2017 |
| Quantifying reproducibility in computational biology: the case of the tuberculosis drugome D Garijo, S Kinnings, L Xie, L Xie, Y Zhang, PE Bourne, Y Gil PloS one 8 (11), e80278, 2013 | 132 | 2013 |
| The Mycobacterium tuberculosis Drugome and Its Polypharmacological Implications SL Kinnings, L Xie, KH Fung, RM Jackson, L Xie, PE Bourne PLoS computational biology 6 (11), e1000976, 2010 | 117 | 2010 |
| Binding site similarity analysis for the functional classification of the protein kinase family SL Kinnings, RM Jackson Journal of Chemical Information and Modeling 49 (2), 318-329, 2009 | 115 | 2009 |
| ReverseScreen3D: a structure-based ligand matching method to identify protein targets SL Kinnings, RM Jackson Journal of chemical information and modeling 51 (3), 624-634, 2011 | 77 | 2011 |
| Circulating transcripts in maternal blood reflect a molecular signature of early-onset preeclampsia S Munchel, S Rohrback, C Randise-Hinchliff, S Kinnings, S Deshmukh, ... Science Translational Medicine 12 (550), eaaz0131, 2020 | 56 | 2020 |
| LigMatch: a multiple structure-based ligand matching method for 3D virtual screening SL Kinnings, RM Jackson Journal of chemical information and modeling 49 (9), 2056-2066, 2009 | 45 | 2009 |
| Predicting the polypharmacology of drugs: identifying new uses through chemoinformatics, structural informatics, and molecular modeling-based approaches L Xie, SL Kinnings, L Xie, PE Bourne Drug Repositioning: Bringing New Life to Shelved Assets and Existing Drugs …, 2012 | 7 | 2012 |
| Circulating RNA signatures specific to preeclampsia SE Shultzaberger, F Kaper, S Kinnings, S Rohrback, C Randise-Hinchliff US Patent 11,753,685, 2023 | | 2023 |
| Circulating rna signatures specific to preeclampsia SE Shultzaberger, F Kaper, S Kinnings, S Rohrback, C Randise-Hinchliff US Patent App. 18/091,186, 2023 | | 2023 |
| System and method for detection of genetic alterations SL Kinnings, C Deciu, M Mehan US Patent App. 17/538,812, 2022 | | 2022 |
| Limit of detection based quality control metric SL Kinnings, C Deciu, B Padhukasahasram, D Skvortsov US Patent App. 17/281,565, 2021 | | 2021 |
| Circulating rna signatures specific to preeclampsia SE Shultzaberger, F Kaper, S Kinnings, S Rohrback, C Randise-Hinchliff US Patent App. 16/620,245, 2021 | | 2021 |
| The structural analysis and prediction of protein-ligand interactions SL Kinnings University of Leeds, 2010 | | 2010 |
Philip E. BourneUniversity of VirginiaVerified email at virginia.edu
