Cleavage site selection within a folded substrate by the ATP-dependent lon protease G Ondrovicová, T Liu, K Singh, B Tian, H Li, O Gakh, D Perecko, J Janata, ... Journal of Biological Chemistry, 2005 | 129 | 2005 |
A New Evolutionary Variant of the Streptogramin A Resistance Protein, Vga(A)LC, from Staphylococcus haemolyticus with Shifted Substrate Specificity towards … G Novotna, J Janata Antimicrobial agents and chemotherapy 50 (12), 4070-4076, 2006 | 98 | 2006 |
Reductive Evolution of the Mitochondrial Processing Peptidases of the Unicellular Parasites Trichomonas vaginalis and Giardia intestinalis O Šmíd, A Matušková, SR Harris, T Kučera, M Novotný, L Horváthová, ... PLoS pathogens 4 (12), e1000243, 2008 | 83 | 2008 |
Sequence analysis and heterologous expression of the lincomycin biosynthetic cluster of the type strain Streptomyces lincolnensis ATCC 25466 M Koběrská, J Kopecký, J Olšovská, M Jelinkova, D Ulanova, P Man, ... Folia microbiologica 53, 395-401, 2008 | 77 | 2008 |
New chalcone-sulfonamide hybrids exhibiting anticancer and antituberculosis activity LF Castaño, V Cuartas, A Bernal, A Insuasty, J Guzman, O Vidal, V Rubio, ... European journal of medicinal chemistry 176, 50-60, 2019 | 70 | 2019 |
Expression and Kinetic Characterization of Methylmalonyl-CoA Mutase from Patients with the Mut− Phenotype: Evidence for Naturally Occurring Interallelic … J Janata, N Kogekar, WA Fenton Human Molecular Genetics 6 (9), 1457-1464, 1997 | 69 | 1997 |
The oral microbiome in periodontal health M Lenartova, B Tesinska, T Janatova, O Hrebicek, J Mysak, J Janata, ... Frontiers in Cellular and Infection Microbiology 11, 629723, 2021 | 64 | 2021 |
Prevalence of resistance mechanisms against macrolides and lincosamides in methicillin-resistant coagulase-negative staphylococci in the Czech Republic and occurrence of an … G Novotna, V Adamkova, J Janata, O Melter, J Spizek Antimicrobial agents and chemotherapy 49 (8), 3586-3589, 2005 | 57 | 2005 |
l‐3,4‐Dihydroxyphenyl alanine‐extradiol cleavage is followed by intramolecular cyclization in lincomycin biosynthesis J Novotna, A Honzatko, P Bednář, J Kopecký, J Janata, J Spížek European journal of biochemistry 271 (18), 3678-3683, 2004 | 54 | 2004 |
High-throughput quantification of lincomycin traces in fermentation broth of genetically modified Streptomyces spp.: Comparison of ultra-performance liquid chromatography and … J Olšovská, M Jelínková, P Man, M Koběrská, J Janata, M Flieger Journal of Chromatography A 1139 (2), 214-220, 2007 | 47 | 2007 |
New concept of the biosynthesis of 4-alkyl-L-proline precursors of lincomycin, hormaomycin, and pyrrolobenzodiazepines: Could a γ-glutamyltransferase cleave the C–C bond? P Jiraskova, R Gazak, Z Kamenik, L Steiningerova, L Najmanova, ... Frontiers in Microbiology 7, 177862, 2016 | 38 | 2016 |
Detailed mutational analysis of Vga (A) interdomain linker: implication for antibiotic resistance specificity and mechanism J Lenart, V Vimberg, L Vesela, J Janata, G Balikova Novotna Antimicrobial agents and chemotherapy 59 (2), 1360-1364, 2015 | 38 | 2015 |
Mutasynthesis of lincomycin derivatives with activity against drug-resistant staphylococci D Ulanova, J Novotná, Y Smutná, Z Kameník, R Gazák, M Šulc, ... Antimicrobial agents and chemotherapy 54 (2), 927-930, 2010 | 38 | 2010 |
Lincomycin biosynthesis involves a tyrosine hydroxylating heme protein of an unusual enzyme family J Novotna, J Olsovska, P Novak, P Mojzes, R Chaloupkova, Z Kamenik, ... PLoS One 8 (12), e79974, 2013 | 37 | 2013 |
Biosynthesis and incorporation of an alkylproline-derivative (APD) precursor into complex natural products J Janata, Z Kamenik, R Gazak, S Kadlcik, L Najmanova Natural product reports 35 (3), 257-289, 2018 | 36 | 2018 |
Lincosamide synthetase—a unique condensation system combining elements of nonribosomal peptide synthetase and mycothiol metabolism J Janata, S Kadlcik, M Koberska, D Ulanova, Z Kamenik, P Novak, ... PLoS One 10 (3), e0118850, 2015 | 34 | 2015 |
Sequence analysis of porothramycin biosynthetic gene cluster L Najmanova, D Ulanova, M Jelinkova, Z Kamenik, E Kettnerova, ... Folia microbiologica 59, 543-552, 2014 | 31 | 2014 |
Glycine-rich loop of mitochondrial processing peptidase α-subunit is responsible for substrate recognition by a mechanism analogous to mitochondrial receptor Tom20 K Dvořáková-Holá, A Matušková, M Kubala, M Otyepka, T Kučera, J Večeř, ... Journal of molecular biology 396 (5), 1197-1210, 2010 | 30 | 2010 |
Adaptation of an L-proline adenylation domain to use 4-propyl-L-proline in the evolution of lincosamide biosynthesis S Kadlčík, T Kučera, D Chalupská, R Gažák, M Koběrská, D Ulanová, ... PLoS One 8 (12), e84902, 2013 | 29 | 2013 |
Characterization of N‐Demethyllincosamide Methyltransferases LmbJ and CcbJ L Najmanová, E Kutejová, J Kadlec, M Polan, J Olšovská, O Benada, ... ChemBioChem 14 (17), 2259-2262, 2013 | 28 | 2013 |