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Laura J Wagstaff
Laura J Wagstaff
Verified email at ed.ac.uk
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Cited by
Cited by
Year
After nerve injury, lineage tracing shows that myelin and Remak Schwann cells elongate extensively and branch to form repair Schwann cells, which shorten radically on remyelination
JA Gomez-Sanchez, KS Pilch, M van der Lans, SV Fazal, C Benito, ...
Journal of Neuroscience 37 (37), 9086-9099, 2017
2242017
Cellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis
AM Nicaise, LJ Wagstaff, CM Willis, C Paisie, H Chandok, P Robson, ...
Proceedings of the National Academy of Sciences 116 (18), 9030-9039, 2019
1752019
Graded elevation of c-Jun in Schwann cells in vivo: gene dosage determines effects on development, remyelination, tumorigenesis, and hypomyelination
SV Fazal, JA Gomez-Sanchez, LJ Wagstaff, N Musner, G Otto, M Janz, ...
Journal of Neuroscience 37 (50), 12297-12313, 2017
792017
Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun
LJ Wagstaff, JA Gomez-Sanchez, SV Fazal, GW Otto, AM Kilpatrick, ...
Elife 10, e62232, 2021
772021
c-Jun activation in Schwann cells protects against loss of sensory axons in inherited neuropathy
J Hantke, L Carty, LJ Wagstaff, M Turmaine, DK Wilton, S Quintes, ...
Brain 137 (11), 2922-2937, 2014
762014
Reprogramming of fibroblasts to oligodendrocyte progenitor-like cells using CRISPR/Cas9-based synthetic transcription factors
M Matjusaitis, LJ Wagstaff, A Martella, B Baranowski, C Blin, S Gogolok, ...
Stem cell reports 13 (6), 1053-1067, 2019
252019
Age-related loss of axonal regeneration is reflected by the level of local translation
S van Erp, AA van Berkel, EM Feenstra, PK Sahoo, LJ Wagstaff, JL Twiss, ...
Experimental Neurology 339, 113594, 2021
82021
The relationship between Schwann cell c-Jun and regeneration failures due to ageing and long-term injury
LJ Wagstaff, JA Gomez-Sanchez, R Mirsky, KR Jessen
13th European Meeting on Glial Cells in Health and Disease, 2017
82017
A reverse genetics and genomics approach to gene paralog function and disease: Myokymia and the juxtaparanode
D Marafi, N Kozar, R Duan, S Bradley, K Yokochi, F Al Mutairi, NW Saadi, ...
The American Journal of Human Genetics 109 (9), 1713-1723, 2022
62022
Manipulation of repair Schwann cells to correct regeneration failures due to chronic denervation and advancing age
KR Jessen, LJ Wagstaff, JA Gomez-Sanchez, R Mirsky
13th European Meeting on Glial Cells in Health and Disease, 2017
22017
Gene expression in rejuvenated repair Schwann cells in aged mice or in chronic injured nerves.
JA Gomez-Sanchez, L Wagstaff, G Otto, R Mirsky, KR Jessen
GLIA 67, E652-E653, 2019
12019
Enhancing remyelination with CRISPR/Cas9 edited human oligodendrocyte progenitor cells
L Wagstaff, M Kaczmarek, A Fidanza, RJM Franklin, AC Williams
GLIA 69, E521-E521, 2021
2021
The well documented failures of nerve repair seen during aging and chronic denervation involve reduced Schwann cell c-Jun, and are rescued by restoring c-Jun levels.
KR Jessen, LJ Wagstaff, JA Gomez-Sanchez, SV Fazal, P Arthur-Farraj, ...
GLIA 69, E88-E89, 2021
2021
Promoting oligodendroglia differentiation from hEScells using an inducible CRISPRa system
T Tsarouchas, L Wagstaff, NL Kazakou, A Williams
GLIA 69, E258-E259, 2021
2021
Enhancing remyelination with CRISPR/Cas9 edited human oligodendrocyte precursor cells
LJ Wagstaff, A Fidanza, RJM Franklin, AC Williams
GLIA 67, E666-E666, 2019
2019
Emerging Drugs and Targets for Remyelination in Multiple Sclerosis
LJ Wagstaff, A Williams
Emerging Drugs and Targets for Multiple Sclerosis 70, 199, 2019
2019
The role of Schwann cell c-Jun in restoring axon regeneration deficits in the peripheral nervous system
LJ Wagstaff
UCL (University College London), 2018
2018
Failures of nerve regeneration caused by aging or chronic denervation are rescued by 2
LJ Wagstaff, JA Gomez-Sanchez, V Fazal, W Otto
METHODS 539, 540, 0
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Articles 1–18