| Novel N-substituted indole Schiff bases as dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase enzymes: Synthesis, biological activities in vitro and docking study PF Lamie, WAM Ali, V Bazgier, L Rárová European journal of medicinal chemistry 123, 803-813, 2016 | 91 | 2016 |
| 3-Methyl-2-phenyl-1-substituted-indole derivatives as indomethacin analogs: design, synthesis and biological evaluation as potential anti-inflammatory and analgesic agents KRA Abdellatif, PF Lamie, HA Omar Journal of Enzyme Inhibition and Medicinal Chemistry 31 (2), 318-324, 2016 | 78 | 2016 |
| Design, Synthesis and Evaluation of Novel Phthalimide Derivatives as in Vitro Anti-Microbial, Anti-Oxidant and Anti-Inflammatory Agents P F. Lamie, J N. Phillopes, A O. El-Gendy, L Rarova, J Gruz Molecules 20 (9), 16620-16642, 2015 | 69 | 2015 |
| Azole-hydrazone derivatives: Design, synthesis, in vitro biological evaluation, dual EGFR/HER2 inhibitory activity, cell cycle analysis and molecular docking study as … MB Labib, JN Philoppes, PF Lamie, ER Ahmed Bioorganic chemistry 76, 67-80, 2018 | 68 | 2018 |
| Novel tetrazole and cyanamide derivatives as inhibitors of cyclooxygenase-2 enzyme: design, synthesis, anti-inflammatory evaluation, ulcerogenic liability and docking study PF Lamie, JN Philoppes, AA Azouz, NM Safwat Journal of enzyme inhibition and medicinal chemistry 32 (1), 805-820, 2017 | 65 | 2017 |
| Cyclooxygenase-2 and 15-lipoxygenase inhibition, synthesis, anti-inflammatory activity and ulcer liability of new celecoxib analogues: Determination of region-specific pyrazole … EKA Abdelall, PF Lamie, WAM Ali Bioorganic & medicinal chemistry letters 26 (12), 2893-2899, 2016 | 53 | 2016 |
| Design and synthesis of new benzoxazole/benzothiazole-phthalimide hybrids as antitumor-apoptotic agents JN Philoppes, PF Lamie Bioorganic chemistry 89, 102978, 2019 | 44 | 2019 |
| A multicomponent reaction to design antimalarial pyridyl-indole derivatives: Synthesis, biological activities and molecular docking HAH Elshemy, MA Zaki, EI Mohamed, SI Khan, PF Lamie Bioorganic Chemistry 97, 103673, 2020 | 40 | 2020 |
| COX-1/COX-2 inhibition assays and histopathological study of the new designed anti-inflammatory agent with a pyrazolopyrimidine core EKA Abdelall, PF Lamie, AKM Ahmed, ELN EL-Shaymaa Bioorganic chemistry 86, 235-253, 2019 | 40 | 2019 |
| New pyrazole derivatives possessing amino/methanesulphonyl pharmacophore with good gastric safety profile: Design, synthesis, cyclooxygenase inhibition, anti-inflammatory … KRA Abdellatif, EKA Abdelall, PF Lamie, MB Labib, ES El-Nahaas, ... Bioorganic chemistry 95, 103540, 2020 | 37 | 2020 |
| Pyrazolo [3, 4-d] pyrimidine-based dual EGFR T790M/HER2 inhibitors: design, synthesis, structure–activity relationship and biological activity as potential antitumor and … PF Lamie, AM El-Kalaawy, NSA Latif, LA Rashed, JN Philoppes European Journal of Medicinal Chemistry 214, 113222, 2021 | 32 | 2021 |
| 2-Thiopyrimidine/chalcone hybrids: design, synthesis, ADMET prediction, and anticancer evaluation as STAT3/STAT5a inhibitors PF Lamie, JN Philoppes Journal of enzyme inhibition and medicinal chemistry 35 (1), 864-879, 2020 | 28 | 2020 |
| New pyrazolopyrimidine derivatives with anticancer activity: Design, synthesis, PIM-1 inhibition, molecular docking study and molecular dynamics JN Philoppes, MA Khedr, MHA Hassan, G Kamel, PF Lamie Bioorganic Chemistry 100, 103944, 2020 | 27 | 2020 |
| Design, synthesis of new anti-inflammatory agents with a pyrazole core: COX-1/COX-2 inhibition assays, anti-inflammatory, ulcerogenic, histopathological, molecular Modeling … KRA Abdellatif, EKA Abdelall, HAH Elshemy, PF Lamie, E Elnahaas, ... Journal of Molecular Structure 1240, 130554, 2021 | 23 | 2021 |
| Design, synthesis, and biological evaluation of novel 1,2‐diaryl‐4‐substituted‐benzylidene‐5(4H)‐imidazolone derivatives as cytotoxic agents and COX‐2/LOX … PF Lamie, JN Philoppes, L Rárová Archiv der Pharmazie 351 (3-4), 1700311, 2018 | 20 | 2018 |
| Synthesis and antitumor activity of novel pyrazolo [3, 4-d] pyrimidines and related heterocycles MM Kandeel, SM Ali, E ElALL, MA Abdelgawad, PF Lamie Der Pharma Chemica 4, 1704-1715, 2012 | 16 | 2012 |
| Synthesis of new quinolone derivatives linked to benzothiazole or benzoxazole moieties as anticancer and anti-oxidant agents MA Abdelgawad, PF Lamie, OM Ahmed Med. Chem 6 (10), 652-657, 2016 | 14 | 2016 |
| Design, synthesis, stereochemical determination, molecular docking study, in silico pre-ADMET prediction and anti-proliferative activities of indole-pyrimidine derivatives as … PF Lamie, JN Philoppes Bioorganic Chemistry 116, 105335, 2021 | 13 | 2021 |
| Synthesis and antitumor activity of novel pyrazolo [3, 4-d] pyrimidin-4 (5H)-one derivatives MM Kandeel, SM Ali, EKAA El All, MA Abdelgawad, PF Lamie J. Chem. Pharm. Res 4 (9), 4097-4106, 2012 | 13 | 2012 |
| Synthesis and antitumor activity of novel pyrazolo [3, 4-d] pyrimidin-4 (5H)-one derivatives MM Kandeel, SM Ali, EKAA El All, MA Abdelgawad, PF Lamie J. Chem. Pharm. Res 4 (9), 4097-4106, 2012 | 13 | 2012 |
