Phase separation and toxicity of C9orf72 poly (PR) depends on alternate distribution of arginine C Chen, Y Yamanaka, K Ueda, P Li, T Miyagi, Y Harada, S Tezuka, ... Journal of Cell Biology 220 (11), e202103160, 2021 | 24 | 2021 |
An improved macromolecular crowding sensor CRONOS for detection of crowding changes in membrane-less organelles under stressed conditions T Miyagi, Y Yamanaka, Y Harada, S Narumi, Y Hayamizu, M Kuroda, ... Biochemical and Biophysical Research Communications 583, 29-34, 2021 | 9 | 2021 |
The patterning and proportion of charged residues in the arginine-rich mixed-charge domain determine the membrane-less organelle targeted by the protein T Miyagi, R Yamazaki, K Ueda, S Narumi, Y Hayamizu, H Uji-i, M Kuroda, ... International journal of molecular sciences 23 (14), 7658, 2022 | 7 | 2022 |
Establishment of chemically oligomerizable TAR DNA-binding protein-43 which mimics amyotrophic lateral sclerosis pathology in mammalian cells Y Yamanaka, T Miyagi, Y Harada, M Kuroda, K Kanekura Laboratory Investigation 101 (10), 1331-1340, 2021 | 7 | 2021 |
Differential toxicity and localization of arginine-rich C9ORF72 dipeptide repeat proteins depend on de-clustering of positive charges T Miyagi, K Ueda, M Sugimoto, T Yagi, D Ito, R Yamazaki, S Narumi, ... Iscience 26 (6), 2023 | 2 | 2023 |
Chemically oligomerizable TDP-43: a novel chemogenetic tool for studying the pathophysiology of amyotrophic lateral sclerosis K Kanekura, Y Yamanaka, T Miyagi, M Kuroda Neural Regeneration Research 17 (11), 2434-2436, 2022 | 2 | 2022 |
An improved molecular crowding sensor CRONOS for detection of crowding changes in membrane-less organelles under pathological conditions T Miyagi, Y Yamanaka, Y Harada, S Narumi, Y Hayamizu, M Kuroda, ... BioRxiv, 2021.03. 31.437991, 2021 | 1 | 2021 |
Disulfide bonds of thyroid peroxidase are critical elements for subcellular localization, proteasome-dependent degradation, and enzyme activity H Iwasaki, H Suwanai, F Yakou, H Sakai, K Ishii, N Hara, AM Buckle, ... Thyroid, 2024 | | 2024 |
Intricate roles of spacers and stickers of Arg-rich C9ORF72 dipeptide repeat proteins; from toxicity to targeting to membraneless organelles K Kanekura, T Miyagi Organelle 1 (1), 2023 | | 2023 |