| Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cells TH Kim, S Escudero, RA Shivdasani Proceedings of the National Academy of Sciences of the United States of …, 2012 | 283 | 2012 |
| Broadly permissive intestinal chromatin underlies lateral inhibition and cell plasticity TH Kim, F Li, I Ferreiro-Neira, LL Ho, A Luyten, K Nalapareddy, H Long, ... Nature 506 (7489), 511-5, 2014 | 256 | 2014 |
| Downregulation of Spry2 by miR-21 triggers malignancy in human gliomas HJ Kwak, YJ Kim, KR Chun, YM Woo, SJ Park, JA Jeong, SH Jo, TH Kim, ... Oncogene 30 (21), 2433-2442, 2011 | 174 | 2011 |
| Stomach development, stem cells and disease TH Kim, RA Shivdasani Development 143 (4), 554-565, 2016 | 168 | 2016 |
| Notch signaling in stomach epithelial stem cell homeostasis TH Kim, RA Shivdasani The Journal of Experimental Medicine 208 (4), 677-88, 2011 | 122 | 2011 |
| Genetic evidence that intestinal Notch functions vary regionally and operate through a common mechanism of Math1 repression TH Kim, RA Shivdasani The Journal of Biological Chemistry 286 (13), 11427-33, 2011 | 111 | 2011 |
| Phactr4 regulates neural tube and optic fissure closure by controlling PP1-, Rb-, and E2F1-regulated cell-cycle progression TH Kim, J Goodman, KV Anderson, L Niswander Developmental Cell 13 (1), 87-102, 2007 | 108 | 2007 |
| Single-cell transcript profiles reveal multilineage priming in early progenitors derived from Lgr5+ intestinal stem cells TH Kim, A Saadatpour, G Guo, M Saxena, A Cavazza, N Desai, U Jadhav, ... Cell reports 16 (8), 2053-2060, 2016 | 97 | 2016 |
| Single cell and genetic analyses reveal conserved populations and signaling mechanisms of gastrointestinal stromal niches JE Kim, L Fei, WC Yin, S Coquenlorge, A Rao-Bhatia, X Zhang, SSW Shi, ... Nature communications 11 (1), 334, 2020 | 86 | 2020 |
| Phactr4 regulates directional migration of enteric neural crest through PP1, integrin signaling, and cofilin activity Y Zhang, TH Kim, L Niswander Genes & Development 26 (1), 69-81, 2012 | 75 | 2012 |
| Enteric glial cell heterogeneity regulates intestinal stem cell niches MB Baghdadi, A Ayyaz, S Coquenlorge, B Chu, S Kumar, C Streutker, ... Cell stem cell 29 (1), 86-100. e6, 2022 | 69 | 2022 |
| Endodermal Hedgehog signals modulate Notch pathway activity in the developing digestive tract mesenchyme TH Kim, BM Kim, J Mao, S Rowan, RA Shivdasani Development 138 (15), 3225-33, 2011 | 49 | 2011 |
| Hedgehog-activated Fat4 and PCP pathways mediate mesenchymal cell clustering and villus formation in gut development A Rao-Bhatia, M Zhu, WC Yin, S Coquenlorge, X Zhang, J Woo, Y Sun, ... Developmental cell 52 (5), 647-658. e6, 2020 | 45 | 2020 |
| Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals T Yung, F Poon, M Liang, S Coquenlorge, EC McGaugh, C Hui, ... Nature communications 10 (1), 4647, 2019 | 38 | 2019 |
| GLI2 modulated by SUFU and SPOP induces intestinal stem cell niche signals in development and tumorigenesis S Coquenlorge, WC Yin, T Yung, J Pan, X Zhang, R Mo, J Belik, C Hui, ... Cell Reports 27 (10), 3006-3018. e4, 2019 | 36 | 2019 |
| Gastrointestinal transcription factors drive lineage-specific developmental programs in organ specification and cancer R Francis, H Guo, C Streutker, M Ahmed, T Yung, PB Dirks, HH He, ... Science Advances 5 (12), eaax8898, 2019 | 31 | 2019 |
| Signaling and epigenetic mechanisms of intestinal stem cells and progenitors: insight into crypt homeostasis, plasticity, and niches RJ Smith, A Rao‐Bhatia, TH Kim Wiley Interdisciplinary Reviews: Developmental Biology 6 (5), e281, 2017 | 27 | 2017 |
| Gut microbiota promotes stem cell differentiation through macrophage and mesenchymal niches in early postnatal development JE Kim, B Li, L Fei, R Horne, D Lee, AKH Loe, H Miyake, E Ayar, M Gurma, ... Immunity 55 (12), 2300-2317. e6, 2022 | 22 | 2022 |
| Uncovering the dosage-dependent roles of Arid1a in gastric tumorigenesis for combinatorial drug therapy AKH Loe, R Francis, J Seo, L Du, Y Wang, JE Kim, SW Hakim, JE Kim, ... Journal of Experimental Medicine 218 (6), e20200219, 2021 | 17 | 2021 |
| Mesenchymal niches for digestive organ development, homeostasis, and disease AKH Loe, A Rao-Bhatia, JE Kim, TH Kim Trends in Cell Biology 31 (3), 152-165, 2021 | 15 | 2021 |
Ramesh ShivdasaniProfessor of Medicine, Dana-Farber Cancer Institute and Harvard Medical SchoolVerified email at dfci.harvard.edu
