Howard Y. Chang
Howard Y. Chang
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Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
RA Gupta, N Shah, KC Wang, J Kim, HM Horlings, DJ Wong, MC Tsai, ...
nature 464 (7291), 1071-1076, 2010
Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
JD Buenrostro, PG Giresi, LC Zaba, HY Chang, WJ Greenleaf
Nature methods 10 (12), 1213-1218, 2013
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs
JL Rinn, M Kertesz, JK Wang, SL Squazzo, X Xu, SA Brugmann, ...
cell 129 (7), 1311-1323, 2007
Molecular mechanisms of long noncoding RNAs
KC Wang, HY Chang
Molecular cell 43 (6), 904-914, 2011
Genome regulation by long noncoding RNAs
JL Rinn, HY Chang
Annual review of biochemistry 81, 2012
Long noncoding RNA as modular scaffold of histone modification complexes
MC Tsai, O Manor, Y Wan, N Mosammaparast, JK Wang, F Lan, Y Shi, ...
Science 329 (5992), 689-693, 2010
Unique features of long non-coding RNA biogenesis and function
JJ Quinn, HY Chang
Nature Reviews Genetics 17 (1), 47-62, 2016
Long noncoding RNAs in cancer pathways
AM Schmitt, HY Chang
Cancer cell 29 (4), 452-463, 2016
Long noncoding RNAs: cellular address codes in development and disease
PJ Batista, HY Chang
Cell 152 (6), 1298-1307, 2013
ATAC‐seq: a method for assaying chromatin accessibility genome‐wide
JD Buenrostro, B Wu, HY Chang, WJ Greenleaf
Current protocols in molecular biology 109 (1), 21.29. 1-21.29. 9, 2015
Long noncoding RNAs and human disease
O Wapinski, HY Chang
Trends in cell biology 21 (6), 354-361, 2011
A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression
KC Wang, YW Yang, B Liu, A Sanyal, R Corces-Zimmerman, Y Chen, ...
Nature 472 (7341), 120-124, 2011
Single-cell chromatin accessibility reveals principles of regulatory variation
JD Buenrostro, B Wu, UM Litzenburger, D Ruff, ML Gonzales, MP Snyder, ...
Nature 523 (7561), 486-490, 2015
Diversity, topographic differentiation, and positional memory in human fibroblasts
HY Chang, JT Chi, S Dudoit, C Bondre, M van de Rijn, D Botstein, ...
Proceedings of the National Academy of Sciences 99 (20), 12877-12882, 2002
Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters
T Hung, Y Wang, MF Lin, AK Koegel, Y Kotake, GD Grant, HM Horlings, ...
Nature genetics 43 (7), 621-629, 2011
Daxx, a novel Fas-binding protein that activates JNK and apoptosis
X Yang, R Khosravi-Far, HY Chang, D Baltimore
Cell 89 (7), 1067-1076, 1997
Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions
C Chu, K Qu, FL Zhong, SE Artandi, HY Chang
Molecular cell 44 (4), 667-678, 2011
An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues
MR Corces, AE Trevino, EG Hamilton, PG Greenside, ...
Nature methods 14 (10), 959-962, 2017
Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival
HY Chang, DSA Nuyten, JB Sneddon, T Hastie, R Tibshirani, T Sørlie, ...
Proceedings of the national academy of sciences 102 (10), 3738-3743, 2005
Proteases for cell suicide: functions and regulation of caspases
HY Chang, X Yang
Microbiology and molecular biology reviews 64 (4), 821-846, 2000
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