| Inhibition of mitochondrial translation overcomes venetoclax resistance in AML through activation of the integrated stress response D Sharon, S Cathelin, S Mirali, JM Di Trani, DJ Yanofsky, KA Keon, ... Science translational medicine 11 (516), eaax2863, 2019 | 149 | 2019 |
| Nicotinamide phosphoribosyltransferase inhibitors selectively induce apoptosis of AML stem cells by disrupting lipid homeostasis A Subedi, Q Liu, DM Ayyathan, D Sharon, S Cathelin, M Hosseini, C Xu, ... Cell Stem Cell 28 (10), 1851-1867. e8, 2021 | 56 | 2021 |
| The mitochondrial transacylase, tafazzin, regulates AML stemness by modulating intracellular levels of phospholipids AK Seneviratne, M Xu, JJA Henao, VA Fajardo, Z Hao, V Voisin, GW Xu, ... Cell stem cell 24 (4), 621-636. e16, 2019 | 52 | 2019 |
| Aberrant expression and biological significance of Sox2, an embryonic stem cell transcriptional factor, in ALK-positive anaplastic large cell lymphoma P Gelebart, SA Hegazy, P Wang, KM Bone, M Anand, D Sharon, M Hitt, ... Blood cancer journal 2 (8), e82-e82, 2012 | 46 | 2012 |
| Disrupting mitochondrial copper distribution inhibits leukemic stem cell self-renewal RP Singh, DV Jeyaraju, V Voisin, R Hurren, C Xu, JR Hawley, ... Cell Stem Cell 26 (6), 926-937. e10, 2020 | 43 | 2020 |
| Aberrant expression of the transcriptional factor Twist1 promotes invasiveness in ALK-positive anaplastic large cell lymphoma J Zhang, P Wang, F Wu, M Li, D Sharon, RJ Ingham, M Hitt, TP McMullen, ... Cellular Signalling 24 (4), 852-858, 2012 | 42 | 2012 |
| The mitochondrial peptidase, neurolysin, regulates respiratory chain supercomplex formation and is necessary for AML viability S Mirali, A Botham, V Voisin, C Xu, J St-Germain, D Sharon, FW Hoff, ... Science Translational Medicine 12 (538), eaaz8264, 2020 | 39 | 2020 |
| Combination of enasidenib and venetoclax shows superior anti-leukemic activity against IDH2 mutated AML in patient-derived xenograft models S Cathelin, D Sharon, A Subedi, D Cojocari, DC Phillips, JD Leverson, ... Blood, The Journal of the American Society of Hematology 132 (Supplement 1 …, 2018 | 30 | 2018 |
| Breast cancer gene therapy using an adenovirus encoding human IL-2 under control of mammaglobin promoter/enhancer sequences S Chaurasiya, P Hew, P Crosley, D Sharon, K Potts, K Agopsowicz, ... Cancer Gene Therapy 23 (6), 178-187, 2016 | 30 | 2016 |
| Impact of combination antiretroviral therapy in the NOD. c3c4 mouse model of autoimmune biliary disease D Sharon, M Chen, G Zhang, S Girgis, B Sis, D Graham, C McDougall, ... Liver International 35 (4), 1442-1450, 2015 | 26 | 2015 |
| HER3 targeting of adenovirus by fiber modification increases infection of breast cancer cells in vitro, but not following intratumoral injection in mice SH MacLeod, MM Elgadi, G Bossi, U Sankar, A Pisio, K Agopsowicz, ... Cancer gene therapy 19 (12), 888-898, 2012 | 25 | 2012 |
| Role of novel retroviruses in chronic liver disease: assessing the link of human betaretrovirus with primary biliary cirrhosis D Sharon, AL Mason Current Infectious Disease Reports 17, 1-10, 2015 | 20 | 2015 |
| The expression and oncogenic effects of the embryonic stem cell marker SALL4 in ALK-positive anaplastic large cell lymphoma P Wang, JD Zhang, F Wu, X Ye, D Sharon, M Hitt, TP McMullen, ... Cellular signalling 24 (10), 1955-1963, 2012 | 18 | 2012 |
| Pericentriolar targeting of the mouse mammary tumor virus GAG protein G Zhang, D Sharon, J Jovel, L Liu, E Wine, N Tahbaz, S Indik, A Mason PLoS One 10 (6), e0131515, 2015 | 11 | 2015 |
| Enasidenib-induced differentiation promotes sensitivity to venetoclax in IDH2-mutated acute myeloid leukemia S Cathelin, D Sharon, A Subedi, D Cojocari, DC Phillips, JD Leverson, ... Leukemia 36 (3), 869-872, 2022 | 10 | 2022 |
| 2-aminopurine enhances the oncolytic activity of an E1b-deleted adenovirus in hepatocellular carcinoma cells D Sharon, M Schümann, S MacLeod, R McPherson, S Chaurasiya, ... PLoS One 8 (6), e65222, 2013 | 7 | 2013 |
| Activity of eftozanermin alfa plus venetoclax in preclinical models and patients with acute myeloid leukemia SK Tahir, E Calvo, BA Carneiro, J Yuda, A Shreenivas, ... Blood Journal, blood. 2022017333, 2023 | 5 | 2023 |
| Virological footprint of T-Cell responses in patients with primary biliary cirrhosis M Rahbari, D Sharon, A Landi, M Houghton, A Mason Canadian Journal of Gastroenterology and Hepatology 29, 159A, 2015 | 5 | 2015 |
| Targeting the mitochondrial metallochaperone Cox17 reduces DNA methylation and promotes AML differentiation through a copper dependent mechanism RP Singh, DV Jeyaraju, V Voisin, C Xu, SH Barghout, DH Khan, R Hurren, ... Blood 132, 1339, 2018 | 4 | 2018 |
| Cholangiocytes from patients with primary biliary cholangitis display the Warburg effect with increased mitochondria, oxygen consumption and glycolytic activity F Wysokinski, B Meng, W Wang, I Wong, J Bintner, C McDougall, ... Hepatology 66, 933A-934A, 2017 | 3 | 2017 |
