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Kathy N. Lam
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C2H2 zinc finger proteins greatly expand the human regulatory lexicon
HS Najafabadi, S Mnaimneh, FW Schmitges, M Garton, KN Lam, A Yang, ...
Nature biotechnology 33 (5), 555-562, 2015
2632015
Current and future resources for functional metagenomics
KN Lam, J Cheng, K Engel, JD Neufeld, TC Charles
Frontiers in microbiology 6, 1196, 2015
1162015
Sequence specificity is obtained from the majority of modular C2H2 zinc-finger arrays
KN Lam, H Van Bakel, AG Cote, A Van Der Ven, TR Hughes
Nucleic acids research 39 (11), 4680-4690, 2011
1002011
Precision medicine goes microscopic: engineering the microbiome to improve drug outcomes
KN Lam, M Alexander, PJ Turnbaugh
Cell host & microbe 26 (1), 22-34, 2019
602019
CRISPR-Cas system of a prevalent human gut bacterium reveals hyper-targeting against phages in a human virome catalog
P Soto-Perez, JE Bisanz, JD Berry, KN Lam, J Bondy-Denomy, ...
Cell host & microbe 26 (3), 325-335. e5, 2019
292019
Phage-delivered CRISPR-Cas9 for strain-specific depletion and genomic deletions in the gut microbiome
KN Lam, P Spanogiannopoulos, P Soto-Perez, M Alexander, MJ Nalley, ...
Cell reports 37 (5), 109930, 2021
242021
Strong spurious transcription likely contributes to DNA insert bias in typical metagenomic clone libraries
KN Lam, TC Charles
Microbiome 3 (1), 1-11, 2015
232015
A genomic toolkit for the mechanistic dissection of intractable human gut bacteria
JE Bisanz, P Soto-Perez, C Noecker, AA Aksenov, KN Lam, GE Kenney, ...
Cell host & microbe 27 (6), 1001-1013. e9, 2020
222020
Identification and characterization of the intracellular poly-3-hydroxybutyrate depolymerase enzyme PhaZ of Sinorhizobium meliloti
MA Trainer, D Capstick, A Zachertowska, KN Lam, SRD Clark, TC Charles
BMC microbiology 10 (1), 1-10, 2010
212010
Evaluation of a pooled strategy for high-throughput sequencing of cosmid clones from metagenomic libraries
KN Lam, MW Hall, K Engel, G Vey, J Cheng, JD Neufeld, TC Charles
PLoS One 9 (6), e98968, 2014
182014
Illuminating the microbiome’s dark matter: a functional genomic toolkit for the study of human gut Actinobacteria
JE Bisanz, P Soto-Perez, KN Lam, EN Bess, HJ Haiser, E Allen-Vercoe, ...
BioRxiv, 304840, 2018
142018
Current and future resources for functional metagenomics. Front Microbiol 6: 1196
KN Lam, J Cheng, K Engel, JD Neufeld, TC Charles
82015
Developing a Bacteroides System for Function-Based Screening of DNA from the Human Gut Microbiome
KN Lam, EC Martens, TC Charles
Msystems 3 (3), e00195-17, 2018
52018
Metagenomic cosmid libraries suitable for functional screening in proteobacteria
J Cheng, KN Lam, K Engel, M Hall, JD Neufeld, TC Charles
Functional Metagenomics: Tools and Applications, 1-11, 2017
42017
Drug resistant gut bacteria mimic a host mechanism for anticancer drug clearance
P Spanogiannopoulos, PH Bradley, J Melamed, YNA Malig, KN Lam, ...
bioRxiv, 820084, 2019
22019
CRISPR-Cas Immune System of a Prevalent Human Gut Bacterium Reveals Hypertargeting Against Gut Virome Phages
P Soto-Perez, JE Bisanz, JD Berry, KN Lam, J Bondy-Denomy, ...
Available at SSRN 3363840, 2019
2019
Development and analysis of molecular methods for functional metagenomics of the human gut microbiome
KN Lam
University of Waterloo, 2016
2016
Research article Identification and characterization of the intracellular poly-3-hydroxybutyrate depolymerase enzyme PhaZ of Sinorhizobium meliloti
MA Trainer, D Capstick, A Zachertowska, KN Lam, SRD Clark, TC Charles
2010
A Phage Display System to Profile the DNA-Binding Specificities of C2H2 Zinc Fingers
KN Lam
University of Toronto (Canada), 2010
2010
Strong spurious transcription likely a cause of DNA insert bias in typical metagenomic clone libraries
KN Lam, TC Charles
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Articles 1–20