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Kathy N. Lam
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C2H2 zinc finger proteins greatly expand the human regulatory lexicon
HS Najafabadi, S Mnaimneh, FW Schmitges, M Garton, KN Lam, A Yang, ...
Nature biotechnology 33 (5), 555-562, 2015
3352015
Current and future resources for functional metagenomics
KN Lam, J Cheng, K Engel, JD Neufeld, TC Charles
Frontiers in microbiology 6, 165114, 2015
1762015
Sequence specificity is obtained from the majority of modular C2H2 zinc-finger arrays
KN Lam, H van Bakel, AG Cote, A van der Ven, TR Hughes
Nucleic acids research 39 (11), 4680-4690, 2011
1152011
Precision medicine goes microscopic: engineering the microbiome to improve drug outcomes
KN Lam, M Alexander, PJ Turnbaugh
Cell host & microbe 26 (1), 22-34, 2019
1002019
Phage-delivered CRISPR-Cas9 for strain-specific depletion and genomic deletions in the gut microbiome
KN Lam, P Spanogiannopoulos, P Soto-Perez, M Alexander, MJ Nalley, ...
Cell Reports 37 (5), 2021
892021
CRISPR-Cas system of a prevalent human gut bacterium reveals hyper-targeting against phages in a human virome catalog
P Soto-Perez, JE Bisanz, JD Berry, KN Lam, J Bondy-Denomy, ...
Cell Host & Microbe 26 (3), 325-335. e5, 2019
532019
A genomic toolkit for the mechanistic dissection of intractable human gut bacteria
JE Bisanz, P Soto-Perez, C Noecker, AA Aksenov, KN Lam, GE Kenney, ...
Cell host & microbe 27 (6), 1001-1013. e9, 2020
452020
Host and gut bacteria share metabolic pathways for anti-cancer drug metabolism
P Spanogiannopoulos, TS Kyaw, BGH Guthrie, PH Bradley, JV Lee, ...
Nature microbiology 7 (10), 1605-1620, 2022
362022
Strong spurious transcription likely contributes to DNA insert bias in typical metagenomic clone libraries
KN Lam, TC Charles
Microbiome 3, 1-11, 2015
272015
Evaluation of a pooled strategy for high-throughput sequencing of cosmid clones from metagenomic libraries
KN Lam, MW Hall, K Engel, G Vey, J Cheng, JD Neufeld, TC Charles
PLoS One 9 (6), e98968, 2014
262014
Identification and characterization of the intracellular poly-3-hydroxybutyrate depolymerase enzyme PhaZ of Sinorhizobium meliloti
MA Trainer, D Capstick, A Zachertowska, KN Lam, SRD Clark, TC Charles
BMC microbiology 10, 1-10, 2010
262010
Illuminating the microbiome’s dark matter: a functional genomic toolkit for the study of human gut Actinobacteria
JE Bisanz, P Soto-Perez, KN Lam, EN Bess, HJ Haiser, E Allen-Vercoe, ...
BioRxiv, 304840, 2018
172018
Current and future resources for functional metagenomics. Front Microbiol 6: 1196
KN Lam, J Cheng, K Engel, JD Neufeld, TC Charles
142015
Developing a Bacteroides System for Function-Based Screening of DNA from the Human Gut Microbiome
KN Lam, EC Martens, TC Charles
Msystems 3 (3), 10.1128/msystems. 00195-17, 2018
122018
Drug resistant gut bacteria mimic a host mechanism for anticancer drug clearance
P Spanogiannopoulos, PH Bradley, J Melamed, YNA Malig, KN Lam, ...
BioRxiv 10, 820084, 2019
52019
Metagenomic cosmid libraries suitable for functional screening in proteobacteria
J Cheng, KN Lam, K Engel, M Hall, JD Neufeld, TC Charles
Functional Metagenomics: Tools and Applications, 1-11, 2017
42017
Detection of non-small cell lung and bladder cancer signatures in peripheral blood using a novel antibody-free chromatin capture assay
K Lai, K Dilger, R Cunningham, T Barnes, K Truong, K Lam, R Boquiren, ...
Cancer Research 84 (6_Supplement), 5028-5028, 2024
2024
Extracting Regulatory Active Chromatin Footprint from Cell-Free DNA
K Lai, K Dilger, R Cunningham, K Lam, R Boquiren, K Troung, M Louie, ...
2024
Extracting Regulatory Active Chromatin Footprint from Cell-Free DNA
D Abdueva, K Lai, K Dilger, R Cunningham, K Lam, R Boquiren, K Troung, ...
2024
Phage-mediated delivery of genes to gut microbiome
K Lam, P Spanogiannopoulos, P Turnbaugh
US Patent App. 17/923,865, 2023
2023
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