| C2H2 zinc finger proteins greatly expand the human regulatory lexicon HS Najafabadi, S Mnaimneh, FW Schmitges, M Garton, KN Lam, A Yang, ... Nature biotechnology 33 (5), 555-562, 2015 | 263 | 2015 |
| Current and future resources for functional metagenomics KN Lam, J Cheng, K Engel, JD Neufeld, TC Charles Frontiers in microbiology 6, 1196, 2015 | 116 | 2015 |
| Sequence specificity is obtained from the majority of modular C2H2 zinc-finger arrays KN Lam, H Van Bakel, AG Cote, A Van Der Ven, TR Hughes Nucleic acids research 39 (11), 4680-4690, 2011 | 100 | 2011 |
| Precision medicine goes microscopic: engineering the microbiome to improve drug outcomes KN Lam, M Alexander, PJ Turnbaugh Cell host & microbe 26 (1), 22-34, 2019 | 60 | 2019 |
| CRISPR-Cas system of a prevalent human gut bacterium reveals hyper-targeting against phages in a human virome catalog P Soto-Perez, JE Bisanz, JD Berry, KN Lam, J Bondy-Denomy, ... Cell host & microbe 26 (3), 325-335. e5, 2019 | 29 | 2019 |
| Phage-delivered CRISPR-Cas9 for strain-specific depletion and genomic deletions in the gut microbiome KN Lam, P Spanogiannopoulos, P Soto-Perez, M Alexander, MJ Nalley, ... Cell reports 37 (5), 109930, 2021 | 24 | 2021 |
| Strong spurious transcription likely contributes to DNA insert bias in typical metagenomic clone libraries KN Lam, TC Charles Microbiome 3 (1), 1-11, 2015 | 23 | 2015 |
| A genomic toolkit for the mechanistic dissection of intractable human gut bacteria JE Bisanz, P Soto-Perez, C Noecker, AA Aksenov, KN Lam, GE Kenney, ... Cell host & microbe 27 (6), 1001-1013. e9, 2020 | 22 | 2020 |
| Identification and characterization of the intracellular poly-3-hydroxybutyrate depolymerase enzyme PhaZ of Sinorhizobium meliloti MA Trainer, D Capstick, A Zachertowska, KN Lam, SRD Clark, TC Charles BMC microbiology 10 (1), 1-10, 2010 | 21 | 2010 |
| Evaluation of a pooled strategy for high-throughput sequencing of cosmid clones from metagenomic libraries KN Lam, MW Hall, K Engel, G Vey, J Cheng, JD Neufeld, TC Charles PLoS One 9 (6), e98968, 2014 | 18 | 2014 |
| Illuminating the microbiome’s dark matter: a functional genomic toolkit for the study of human gut Actinobacteria JE Bisanz, P Soto-Perez, KN Lam, EN Bess, HJ Haiser, E Allen-Vercoe, ... BioRxiv, 304840, 2018 | 14 | 2018 |
| Current and future resources for functional metagenomics. Front Microbiol 6: 1196 KN Lam, J Cheng, K Engel, JD Neufeld, TC Charles | 8 | 2015 |
| Developing a Bacteroides System for Function-Based Screening of DNA from the Human Gut Microbiome KN Lam, EC Martens, TC Charles Msystems 3 (3), e00195-17, 2018 | 5 | 2018 |
| Metagenomic cosmid libraries suitable for functional screening in proteobacteria J Cheng, KN Lam, K Engel, M Hall, JD Neufeld, TC Charles Functional Metagenomics: Tools and Applications, 1-11, 2017 | 4 | 2017 |
| Drug resistant gut bacteria mimic a host mechanism for anticancer drug clearance P Spanogiannopoulos, PH Bradley, J Melamed, YNA Malig, KN Lam, ... bioRxiv, 820084, 2019 | 2 | 2019 |
| CRISPR-Cas Immune System of a Prevalent Human Gut Bacterium Reveals Hypertargeting Against Gut Virome Phages P Soto-Perez, JE Bisanz, JD Berry, KN Lam, J Bondy-Denomy, ... Available at SSRN 3363840, 2019 | | 2019 |
| Development and analysis of molecular methods for functional metagenomics of the human gut microbiome KN Lam University of Waterloo, 2016 | | 2016 |
| Research article Identification and characterization of the intracellular poly-3-hydroxybutyrate depolymerase enzyme PhaZ of Sinorhizobium meliloti MA Trainer, D Capstick, A Zachertowska, KN Lam, SRD Clark, TC Charles | | 2010 |
| A Phage Display System to Profile the DNA-Binding Specificities of C2H2 Zinc Fingers KN Lam University of Toronto (Canada), 2010 | | 2010 |
| Strong spurious transcription likely a cause of DNA insert bias in typical metagenomic clone libraries KN Lam, TC Charles | | |
