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Juha Mehtonen
Juha Mehtonen
Verified email at helsinki.fi
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FinnGen provides genetic insights from a well-phenotyped isolated population
MI Kurki, J Karjalainen, P Palta, TP Sipilä, K Kristiansson, KM Donner, ...
Nature 613 (7944), 508-518, 2023
9912023
Mapping the human genetic architecture of COVID-19
Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ...
Nature 600 (7889), 472-477, 2021
7772021
Immunogenomic landscape of hematological malignancies
O Dufva, P Pölönen, O Brück, MAI Keränen, J Klievink, J Mehtonen, ...
Cancer Cell 38 (3), 380-399. e13, 2020
1482020
Analysis of primary microRNA loci from nascent transcriptomes reveals regulatory domains governed by chromatin architecture
M Bouvy-Liivrand, A Hernández de Sande, P Pölönen, J Mehtonen, ...
Nucleic acids research 45 (17), 9837-9849, 2017
552017
Transcription-coupled genetic instability marks acute lymphoblastic leukemia structural variation hotspots
M Heinäniemi, T Vuorenmaa, S Teppo, MU Kaikkonen, M Bouvy-Liivrand, ...
Elife 5, e13087, 2016
442016
In silico and preclinical drug screening identifies dasatinib as a targeted therapy for T-ALL
S Laukkanen, T Grönroos, P Pölönen, H Kuusanmäki, J Mehtonen, ...
Blood cancer journal 7 (9), e604-e604, 2017
322017
Hemap: An Interactive Online Resource for Characterizing Molecular Phenotypes across Hematologic Malignancies
P Pölönen, J Mehtonen, J Lin, T Liuksiala, S Häyrynen, S Teppo, ...
Cancer research 79 (10), 2466-2479, 2019
292019
Single cell characterization of B-lymphoid differentiation and leukemic cell states during chemotherapy in ETV6-RUNX1-positive pediatric leukemia identifies drug-targetable …
J Mehtonen, S Teppo, M Lahnalampi, A Kokko, R Kaukonen, L Oksa, ...
Genome Medicine 12 (1), 2020
252020
Semisupervised generative autoencoder for single-cell data
TN Trong, J Mehtonen, G González, R Kramer, V Hautamäki, ...
Journal of Computational Biology 27 (8), 1190-1203, 2020
20*2020
Data-driven characterization of molecular phenotypes across heterogeneous sample collections
J Mehtonen, P Pölönen, S Häyrynen, O Dufva, J Lin, T Liuksiala, ...
Nucleic acids research 47 (13), e76-e76, 2019
202019
IGF2BP3 Associates with Proliferative Phenotype and Prognostic Features in B-Cell Acute Lymphoblastic Leukemia
A Mäkinen, A Nikkilä, T Haapaniemi, L Oksa, J Mehtonen, M Vänskä, ...
Cancers 13 (7), 1505, 2021
132021
Predicting residential radon concentrations in Finland
A Nikkilä, H Arvela, J Mehtonen, J Raitanen, M Heinäniemi, O Lohi, ...
Scandinavian journal of work, environment & health 46 (3), 278-292, 2020
132020
Genetic predictors of lifelong medication-use patterns in cardiometabolic diseases
T Kiiskinen, P Helkkula, K Krebs, J Karjalainen, E Saarentaus, N Mars, ...
Nature medicine 29 (1), 209-218, 2023
122023
Inframe insertion and splice site variants in MFGE8 associate with protection against coronary atherosclerosis
SE Ruotsalainen, I Surakka, N Mars, J Karjalainen, M Kurki, M Kanai, ...
Communications biology 5 (1), 802, 2022
112022
Germline POT1 deregulation can predispose to myeloid malignancies in childhood
P Michler, A Schedel, M Witschas, UA Friedrich, R Wagener, J Mehtonen, ...
International Journal of Molecular Sciences 22 (21), 11572, 2021
102021
Clinicopathological features and prognostic value of SOX11 in childhood acute lymphoblastic leukemia
T Grönroos, A Mäkinen, S Laukkanen, J Mehtonen, A Nikkilä, L Oksa, ...
Scientific reports 10 (1), 2043, 2020
82020
Overlap of genetic loci for central serous chorioretinopathy with age-related macular degeneration
JT Rämö, E Abner, EHC van Dijk, X Wang, J Brinks, T Nikopensius, ...
JAMA ophthalmology 141 (5), 449-457, 2023
72023
Overexpression of PTP4A3 in ETV6-RUNX1 acute lymphoblastic leukemia
T Grönroos, S Teppo, J Mehtonen, S Laukkanen, T Liuksiala, M Nykter, ...
Leukemia Research 54, 1-6, 2017
62017
Distinct and shared genetic architectures of gestational diabetes mellitus and type 2 diabetes
A Elliott, RK Walters, M Pirinen, M Kurki, N Junna, JI Goldstein, MP Reeve, ...
Nature Genetics, 1-6, 2024
52024
Genome-Wide Association Study Identifies 4 Novel Risk Loci for Small Intestinal Neuroendocrine Tumors Including a Missense Mutation in LGR5
AK Giri, M Aavikko, L Wartiovaara, T Lemmetyinen, J Karjalainen, ...
Gastroenterology 165 (4), 861-873, 2023
32023
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