| In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity GM Lynn, R Laga, PA Darrah, AS Ishizuka, AJ Balaci, AE Dulcey, ... Nature biotechnology 33 (11), 1201-1210, 2015 | 410 | 2015 |
| Therapeutic targeting of non-coding RNAs in cancer O Slaby, R Laga, O Sedlacek Biochemical journal 474 (24), 4219-4251, 2017 | 253 | 2017 |
| Peptide–TLR-7/8a conjugate vaccines chemically programmed for nanoparticle self-assembly enhance CD8 T-cell immunity to tumor antigens GM Lynn, C Sedlik, F Baharom, Y Zhu, RA Ramirez-Valdez, VL Coble, ... Nature biotechnology 38 (3), 320-332, 2020 | 245 | 2020 |
| Enhanced tumor uptake and penetration of virotherapy using polymer stealthing and focused ultrasound R Carlisle, J Choi, M Bazan-Peregrino, R Laga, V Subr, L Kostka, ... Journal of the National Cancer Institute 105 (22), 1701-1710, 2013 | 128 | 2013 |
| Polymer conjugates of doxorubicin bound through an amide and hydrazone bond: Impact of the carrier structure onto synergistic action in the treatment of solid tumours T Etrych, V Šubr, R Laga, B Říhová, K Ulbrich European Journal of Pharmaceutical Sciences 58, 1-12, 2014 | 86 | 2014 |
| Coating of DNA/Poly(l-lysine) Complexes by Covalent Attachment of Poly[N-(2-hydroxypropyl)methacrylamide] V Šubr, Č Koňák, R Laga, K Ulbrich Biomacromolecules 7 (1), 122-130, 2006 | 75 | 2006 |
| Polymer coatings for delivery of nucleic acid therapeutics R Laga, R Carlisle, M Tangney, K Ulbrich, LW Seymour Journal of controlled release 161 (2), 537-553, 2012 | 70 | 2012 |
| Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies WB Williams, RR Meyerhoff, RJ Edwards, H Li, K Manne, NI Nicely, ... Cell 184 (11), 2955-2972. e25, 2021 | 65 | 2021 |
| Thermoresponsive polymer nanoparticles co-deliver RSV F trimers with a TLR-7/8 adjuvant JR Francica, GM Lynn, R Laga, MG Joyce, TJ Ruckwardt, KM Morabito, ... Bioconjugate Chemistry 27 (10), 2372-2385, 2016 | 57 | 2016 |
| Coiled coil peptides as universal linkers for the attachment of recombinant proteins to polymer therapeutics M Pechar, R Pola, R Laga, K Ulbrich, L Bednárová, P Maloň, I Sieglová, ... Biomacromolecules 12 (10), 3645-3655, 2011 | 55 | 2011 |
| Click chemistry as a powerful and chemoselective tool for the attachment of targeting ligands to polymer drug carriers R Pola, A Braunová, R Laga, M Pechar, K Ulbrich Polymer Chemistry 5 (4), 1340-1350, 2014 | 45 | 2014 |
| Thermoresponsive polymer micelles as potential nanosized cancerostatics R Laga, O Janoušková, K Ulbrich, R Pola, J Blažková, SK Filippov, ... Biomacromolecules 16 (8), 2493-2505, 2015 | 44 | 2015 |
| Coiled Coil Peptides and Polymer–Peptide Conjugates: Synthesis, Self-Assembly, Characterization and Potential in Drug Delivery Systems M Pechar, R Pola, R Laga, A Braunová, SK Filippov, A Bogomolova, ... Biomacromolecules 15 (7), 2590-2599, 2014 | 44 | 2014 |
| Impact of polymer-TLR-7/8 agonist (adjuvant) morphology on the potency and mechanism of CD8 T cell induction GM Lynn, P Chytil, JR Francica, A Lagová, G Kueberuwa, AS Ishizuka, ... Biomacromolecules 20 (2), 854-870, 2019 | 43 | 2019 |
| Polymer therapeutics with a coiled coil motif targeted against murine BCL1 leukemia R Pola, R Laga, K Ulbrich, I Sieglová, V Král, M Fábry, M Kabešová, ... Biomacromolecules 14 (3), 881-889, 2013 | 43 | 2013 |
| Tumor-targeted micelle-forming block copolymers for overcoming of multidrug resistance A Braunová, L Kostka, L Sivák, L Cuchalová, Z Hvězdová, R Laga, ... Journal of controlled release 245, 41-51, 2017 | 40 | 2017 |
| Molecular weight and polydispersity of calf-thymus DNA: static light-scattering and size-exclusion chromatography with dual detection B Porsch, R Laga, J Horský, C Koňák, K Ulbrich Biomacromolecules 10 (11), 3148-3150, 2009 | 40 | 2009 |
| Star nanoparticles delivering HIV-1 peptide minimal immunogens elicit near-native envelope antibody responses in nonhuman primates JR Francica, R Laga, GM Lynn, G Mužíková, L Androvič, B Aussedat, ... PLoS biology 17 (6), e3000328, 2019 | 39 | 2019 |
| Hydrolytically and Reductively Degradable High‐Molecular‐Weight Poly (ethylene glycol) s A Braunova, M Pechar, R Laga, K Ulbrich Macromolecular Chemistry and Physics 208 (24), 2642-2653, 2007 | 37 | 2007 |
| Increasing the density of nanomedicines improves their ultrasound-mediated delivery to tumours S Mo, R Carlisle, R Laga, R Myers, S Graham, R Cawood, K Ulbrich, ... Journal of Controlled Release 210, 10-18, 2015 | 33 | 2015 |
Geoffrey M LynnAvidea TechnologiesE-mailová adresa ověřena na: jhu.edu
