| Chemical biology of epothilones KC Nicolaou, F Roschangar, D Vourloumis Angewandte Chemie International Edition 37 (15), 2014-2045, 1998 | 533 | 1998 |
| Key Green Chemistry research areas from a pharmaceutical manufacturers’ perspective revisited MC Bryan, PJ Dunn, D Entwistle, F Gallou, SG Koenig, JD Hayler, ... Green Chemistry 20 (22), 5082-5103, 2018 | 462 | 2018 |
| Overcoming barriers to green chemistry in the pharmaceutical industry–the Green Aspiration Level™ concept F Roschangar, RA Sheldon, CH Senanayake Green Chemistry 17 (2), 752-768, 2015 | 383 | 2015 |
| Designed Epothilones: Combinatorial Synthesis, Tubulin Assembly Properties, abd Cytotoxic Action against Taxol‐Resistant Tumor Cells KC Nicolaou, D Vourloumis, T Li, J Pastor, N Winssinger, Y He, ... Angewandte Chemie International Edition in English 36 (19), 2097-2103, 1997 | 335 | 1997 |
| The olefin metathesis approach to epothilone A and its analogues KC Nicolaou, Y He, D Vourloumis, H Vallberg, F Roschangar, F Sarabia, ... Journal of the American Chemical Society 119 (34), 7960-7973, 1997 | 332 | 1997 |
| Sustainability challenges in peptide synthesis and purification: from R&D to production A Isidro-Llobet, MN Kenworthy, S Mukherjee, ME Kopach, K Wegner, ... The Journal of organic chemistry 84 (8), 4615-4628, 2019 | 314 | 2019 |
| The first regioselective palladium-catalyzed indolization of 2-bromo-or 2-chloroanilines with internal alkynes: a new approach to 2, 3-disubstituted indoles M Shen, G Li, BZ Lu, A Hossain, F Roschangar, V Farina, ... Organic Letters 6 (22), 4129-4132, 2004 | 173 | 2004 |
| Regioselective palladium-catalyzed arylation of 2-furaldehyde MS McClure, B Glover, E McSorley, A Millar, MH Osterhout, F Roschangar Organic Letters 3 (11), 1677-1680, 2001 | 171 | 2001 |
| Total synthesis of epothilone E and related side-chain modified analogues via a Stille coupling based strategy KC Nicolaou, NP King, MRV Finlay, Y He, F Roschangar, D Vourloumis, ... Bioorganic & medicinal chemistry 7 (5), 665-697, 1999 | 166 | 1999 |
| The eight criteria defining a good chemical manufacturing process R Dach, JJ Song, F Roschangar, W Samstag, CH Senanayake Organic Process Research & Development 16 (11), 1697-1706, 2012 | 145 | 2012 |
| Chemie und Biologie der Epothilone KC Nicolaou, F Roschangar, D Vourloumis Angewandte Chemie 110 (15), 2120-2153, 1998 | 133 | 1998 |
| Total synthesis of epothilone E and analogues with modified side chains through the Stille coupling reaction KC Nicolaou, Y He, F Roschangar, NP King, D Vourloumis, T Li Angewandte Chemie International Edition 37 (1‐2), 84-87, 1998 | 130 | 1998 |
| A deeper shade of green: inspiring sustainable drug manufacturing F Roschangar, J Colberg, PJ Dunn, F Gallou, JD Hayler, SG Koenig, ... Green chemistry 19 (1), 281-285, 2017 | 111 | 2017 |
| Gezielt entworfene Epothilone: kombinatorische Synthese, Induktion der Tubulin‐Polymerisation und cytotoxische Wirkung gegen taxolresistente Tumorzellen KC Nicolaou, D Vourloumis, T Li, J Pastor, N Winssinger, Y He, ... Angewandte Chemie 109 (19), 2181-2187, 1997 | 88 | 1997 |
| Practical total synthesis of (+)-camptothecin: the full story MA Ciufolini, F Roschangar Tetrahedron 53 (32), 11049-11060, 1997 | 83 | 1997 |
| A unified strategy for the synthesis of phenanthroizidine alkaloids: Preparation of sterically congested pyridines MA Ciufolini, F Roschangar Journal of the American Chemical Society 118 (48), 12082-12089, 1996 | 83 | 1996 |
| Inspiring process innovation via an improved green manufacturing metric: iGAL F Roschangar, Y Zhou, DJC Constable, J Colberg, DP Dickson, PJ Dunn, ... Green chemistry 20 (10), 2206-2211, 2018 | 82 | 2018 |
| Efficient Asymmetric Synthesis of Structurally Diverse P‐Stereogenic Phosphinamides for Catalyst Design ZS Han, L Zhang, Y Xu, JD Sieber, MA Marsini, Z Li, JT Reeves, ... Angewandte Chemie 127 (18), 5564-5567, 2015 | 80 | 2015 |
| Total Synthesis of Oxazole‐and Cyclopropane‐Containing Epothilone A Analogues by the Olefin Metathesis Approach KC Nicolaou, H Vallberg, NP King, F Roschangar, Y He, D Vourloumis, ... Chemistry–A European Journal 3 (12), 1957-1970, 1997 | 78 | 1997 |
| Quinazoline ditosylate salt compounds MS McClure, MH Osterhout, F Roschangar, MJ Sacchetti US Patent 7,157,466, 2007 | 73 | 2007 |
Kyriacos NicolaouRice UniversityVerified email at rice.edu
