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Ellen Leffler
Ellen Leffler
Verified email at genetics.utah.edu - Homepage
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Cited by
Year
Revisiting an old riddle: what determines genetic diversity levels within species?
EM Leffler, K Bullaughey, DR Matute, WK Meyer, L Segurel, A Venkat, ...
Public Library of Science 10 (9), e1001388, 2012
5982012
A fine-scale chimpanzee genetic map from population sequencing
A Auton, A Fledel-Alon, S Pfeifer, O Venn, L Ségurel, T Street, EM Leffler, ...
science 336 (6078), 193-198, 2012
3262012
Stable recombination hotspots in birds
S Singhal, EM Leffler, K Sannareddy, I Turner, O Venn, DM Hooper, ...
Science 350 (6263), 928-932, 2015
3192015
Multiple instances of ancient balancing selection shared between humans and chimpanzees
EM Leffler, Z Gao, S Pfeifer, L Ségurel, A Auton, O Venn, R Bowden, ...
Science 339 (6127), 1578-1582, 2013
3172013
A novel locus of resistance to severe malaria in a region of ancient balancing selection
MGE Network
Nature 526, 253–257, 2015
1962015
Resistance to malaria through structural variation of red blood cell invasion receptors
EM Leffler, G Band, GBJ Busby, K Kivinen, QS Le, GM Clarke, KA Bojang, ...
Science 356 (6343), eaam6393, 2017
1772017
Insights into malaria susceptibility using genome-wide data on 17,000 individuals from Africa, Asia and Oceania
Nature communications 10 (1), 5732, 2019
1392019
Variation in human recombination rates and its genetic determinants
A Fledel-Alon, EM Leffler, Y Guan, M Stephens, G Coop, M Przeworski
PloS one 6 (6), e20321, 2011
1232011
Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study
CM Ndila, S Uyoga, AW Macharia, G Nyutu, N Peshu, J Ojal, M Shebe, ...
The Lancet Haematology 5 (8), e333-e345, 2018
1072018
The case of the fickle fingers: how the PRDM9 zinc finger protein specifies meiotic recombination hotspots in humans
L Ségurel, EM Leffler, M Przeworski
PLoS biology 9 (12), e1001211, 2011
1002011
Malaria protection due to sickle haemoglobin depends on parasite genotype
G Band, EM Leffler, M Jallow, F Sisay-Joof, CM Ndila, AW Macharia, ...
Nature 602 (7895), 106-111, 2022
432022
Inferring adaptive gene-flow in recent African history
G Busby, R Christ, G Band, E Leffler, QS Le, K Rockett, D Kwiatkowski, ...
BioRxiv, 205252, 2017
162017
Evolutionary insights from wild vervet genomes
EM Leffler
Nature genetics 49 (12), 1671-1672, 2017
42017
The protective effect of sickle cell haemoglobin against severe malaria depends on parasite genotype
G Band, EM Leffler, M Jallow, F Sisay-Joof, CM Ndila, AW Macharia, ...
bioRxiv, 2021.03. 30.437659, 2021
32021
High-throughput genotyping assays for identification of glycophorin B deletion variants in population studies
DSY Amuzu, KA Rockett, EM Leffler, F Ansah, N Amoako, CM Morang’a, ...
Experimental Biology and Medicine 246 (8), 916-928, 2021
22021
Rapid Evolution of Glycan Recognition Receptors Reveals an Axis of Host–Microbe Arms Races beyond Canonical Protein–Protein Interfaces
ZA Hilbert, PE Haffener, HJ Young, MJW Schwiesow, EM Leffler, NC Elde
Genome Biology and Evolution 15 (7), evad119, 2023
12023
Large-scale genotyping and meta-analysis of PIEZO1 short tandem repeat alleles suggest a modest association with malaria susceptibility
EM Leffler, G Band, AE Jeffreys, K Rowlands, C Hubbart, KA Bojang, ...
bioRxiv, 2024
2024
Adaptive admixture at ACKR1 (the Duffy locus) may have shaped Plasmodium vivax prevalence in Oman
PE Haffener, AZ Al-Riyami, S Al-Zadjali, GBJ Busby, S Al Mahdhuri, ...
bioRxiv, 2024.03. 06.583766, 2024
2024
IMPACT OF MALARIA-PROTECTIVE GLYCOPHORIN POLYMORPHISM ON PLASMODIUM FALCIPARUM INVASION
S Kariuki, A Marin-Menendez, E Leffler, G Band, K Rockett, A Macharia, ...
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 99 (4), 26-26, 2018
2018
Insights Into Natural Selection and Recombination from Patterns of Genetic Variation
E Leffler
University of Chicago, 2013
2013
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