Sledovat
Nizar Y. Saad
Nizar Y. Saad
Assistant Professor, The Research Institute at Nationwide Children's Hospital
E-mailová adresa ověřena na: nationwidechildrens.org - Domovská stránka
Název
Citace
Citace
Rok
Major bioactivities and mechanism of action of essential oils and their components
NY Saad, CD Muller, A Lobstein
Flavour and Fragrance Journal 28 (5), 269-279, 2013
3022013
AAV-mediated follistatin gene therapy improves functional outcomes in the TIC-DUX4 mouse model of FSHD
CR Giesige, LM Wallace, KN Heller, JO Eidahl, NY Saad, AM Fowler, ...
JCI insight 3 (22), 2018
642018
Pre-clinical safety and off-target studies to support translation of AAV-mediated RNAi therapy for FSHD
LM Wallace, NY Saad, NK Pyne, AM Fowler, JO Eidahl, JS Domire, ...
Molecular therapy Methods & clinical development 8, 121-130, 2018
562018
Two-codon T-box riboswitch binding two tRNAs
NY Saad, V Stamatopoulou, M Braye, D Drainas, C Stathopoulos, ...
Proceedings of the National Academy of Sciences 110 (31), 12756-12761, 2013
372013
A ribonucleopeptide world at the origin of life
NY Saad
Journal of systematics and evolution 56 (1), 1-13, 2018
302018
Riboswitch (T-box)-mediated control of tRNA-dependent amidation in Clostridium acetobutylicum rationalizes gene and pathway redundancy for asparagine and asparaginyl-trnaasn …
NY Saad, B Schiel, M Braye, JT Heap, NP Minton, P Duerre, HD Becker
Journal of Biological Chemistry 287 (24), 20382-20394, 2012
252012
Human miRNA miR-675 inhibits DUX4 expression and may be exploited as a potential treatment for Facioscapulohumeral muscular dystrophy
NY Saad, M Al-Kharsan, SE Garwick-Coppens, GA Chermahini, ...
Nature communications 12 (1), 1-18, 2021
212021
A glyS T-box riboswitch with species-specific structural features responding to both proteinogenic and nonproteinogenic tRNAGly isoacceptors
M Apostolidi, NY Saad, D Drainas, S Pournaras, HD Becker, ...
Rna 21 (10), 1790-1806, 2015
192015
The DUX4 protein is a co‐repressor of the progesterone and glucocorticoid nuclear receptors
J Quintero, NY Saad, SM Pagnoni, DK Jacquelin, LV Gatica, SQ Harper, ...
FEBS letters 596 (20), 2644-2658, 2022
42022
Engineering more efficient therapeutic miRNAs for FSHD gene therapy
NY Saad, NK Pyne, J Copeland, SQ Harper
MOLECULAR THERAPY 28 (4), 113-113, 2020
22020
Investigation of the natural miRNA miR-675 as a prospective RNAi-based gene therapy product for facioscapulohumeral muscular dystrophy (FSHD)
NY Saad, GA Chermahini, M Al-Kharsan, S Garwick-Coppens, SQ Harper
MOLECULAR THERAPY 28 (4), 468-468, 2020
12020
Compositions and methods for treating disease associated with dux4 overexpression
N Saad, SQ Harper
US Patent App. 18/274,327, 2024
2024
P65 Development of therapeutic extracellular vesicle enveloped-AAV vectors for muscle gene therapy
J Kauffman, N Saad
Neuromuscular Disorders 33, S75, 2023
2023
Post‐Translational Modifications of the DUX4 Protein Impact Toxic Function in FSHD Cell Models
RN Knox, JO Eidahl, LM Wallace, SG Choudury, A Rashnonejad, ...
Annals of neurology 94 (2), 398-413, 2023
2023
Acknowledgment to the Reviewers of Life in 2022
LE Office
Life 13 (2), 2023
2023
P. 143 Investigation of human bone marrow mesenchymal stem cell-derived extracellular vesicles as therapeutic agents for Facioscapulohumeral muscular dystrophy
L Wallace, S Harper, N Saad
Neuromuscular Disorders 32, S106, 2022
2022
Translating DUX4-Targeted RNAi-Based Gene Therapy for FSHD
LM Wallace, T Riley, N Saad, MJ Guggenbiller, GA Chermahini, ...
MOLECULAR THERAPY 30 (4), 502-502, 2022
2022
Engineering More Efficient Therapeutic miRNAs for FSHD Gene Therapy
NY Saad, LM Wallace, NK Pyne, J Copeland, M Guggenbiller, ...
MOLECULAR THERAPY 30 (4), 279-279, 2022
2022
Acknowledgment to Reviewers of Life in 2021
Life Editorial Office
Life 12 (2), 199, 2022
2022
Acknowledgment to Reviewers of Life in 2020
Life Editorial Office
Life 11 (2), 73, 2021
2021
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Články 1–20