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Villeval Jean-Luc
Villeval Jean-Luc
Director of research, INSERM, Institut Gustave Roussy
Verified email at gustaveroussy.fr
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Cited by
Cited by
Year
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
C James, V Ugo, JP Le Couédic, J Staerk, F Delhommeau, C Lacout, ...
nature 434 (7037), 1144-1148, 2005
45432005
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency
S Hacein-Bey-Abina, C Von Kalle, M Schmidt, F Le Deist, N Wulffraat, ...
New England journal of medicine 348 (3), 255-256, 2003
24202003
Effects of recombinant human granulocyte colony-stimulating factor on hematopoietic progenitor cells in cancer patients
U Duhrsen, JL Villeval, J Boyd, G Kannourakis, G Morstyn, D Metcalf
7821988
JAK2V617F expression in murine hematopoietic cells leads to MPD mimicking human PV with secondary myelofibrosis
C Lacout, DF Pisani, M Tulliez, FM Gachelin, W Vainchenker, JL Villeval
blood 108 (5), 1652-1660, 2006
5542006
Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily
M Jandrot-Perrus, S Busfield, AH Lagrue, X Xiong, N Debili, T Chickering, ...
Blood, The Journal of the American Society of Hematology 96 (5), 1798-1807, 2000
3602000
High thrombopoietin production by hematopoietic cells induces a fatal myeloproliferative syndrome in mice
JL Villeval, K Cohen-Solal, M Tulliez, S Giraudier, J Guichard, SA Burstein, ...
Blood, The Journal of the American Society of Hematology 90 (11), 4369-4383, 1997
3161997
Vector integration is nonrandom and clustered and influences the fate of lymphopoiesis in SCID-X1 gene therapy
A Deichmann, S Hacein-Bey-Abina, M Schmidt, A Garrigue, MH Brugman, ...
The Journal of clinical investigation 117 (8), 2225-2232, 2007
2942007
Calreticulin mutants in mice induce an MPL-dependent thrombocytosis with frequent progression to myelofibrosis
C Marty, C Pecquet, H Nivarthi, M El-Khoury, I Chachoua, M Tulliez, ...
Blood, The Journal of the American Society of Hematology 127 (10), 1317-1324, 2016
2852016
Hematopoietic-specific β1 tubulin participates in a pathway of platelet biogenesis dependent on the transcription factor NF-E2
P Lecine, JE Italiano Jr, SW Kim, JL Villeval, RA Shivdasani
Blood, The Journal of the American Society of Hematology 96 (4), 1366-1373, 2000
2342000
Mice lacking transcription factor NF-E2 provide in vivo validation of the proplatelet model of thrombocytopoiesis and show a platelet production defect that is intrinsic to …
P Lecine, JL Villeval, P Vyas, B Swencki, Y Xu, RA Shivdasani
Blood, The Journal of the American Society of Hematology 92 (5), 1608-1616, 1998
2121998
JAK2 stimulates homologous recombination and genetic instability: potential implication in the heterogeneity of myeloproliferative disorders
I Plo, M Nakatake, L Malivert, JP de Villartay, S Giraudier, JL Villeval, ...
Blood, The Journal of the American Society of Hematology 112 (4), 1402-1412, 2008
1972008
Myeloproliferative neoplasm induced by constitutive expression of JAK2V617F in knock-in mice
C Marty, C Lacout, A Martin, S Hasan, S Jacquot, MC Birling, ...
Blood, The Journal of the American Society of Hematology 116 (5), 783-787, 2010
1912010
A role for reactive oxygen species in JAK2V617F myeloproliferative neoplasm progression
C Marty, C Lacout, N Droin, JP Le Couédic, V Ribrag, E Solary, ...
Leukemia 27 (11), 2187-2195, 2013
1862013
Ultrastructural localization of lactoferrin and myeloperoxidase in human neutrophils by immunogold
E Cramer, KB Pryzwansky, JL Villeval, U Testa, J Breton-Gorius
1851985
Activating mutations in human acute megakaryoblastic leukemia
S Malinge, C Ragu, V Della-Valle, D Pisani, SN Constantinescu, C Perez, ...
Blood, The Journal of the American Society of Hematology 112 (10), 4220-4226, 2008
1682008
JAK2V617F expression in mice amplifies early hematopoietic cells and gives them a competitive advantage that is hampered by IFNα
S Hasan, C Lacout, C Marty, M Cuingnet, E Solary, W Vainchenker, ...
Blood, The Journal of the American Society of Hematology 122 (8), 1464-1477, 2013
1562013
Novel activating JAK2 mutation in a patient with Down syndrome and B-cell precursor acute lymphoblastic leukemia
S Malinge, R Ben-Abdelali, C Settegrana, I Radford-Weiss, M Debre, ...
Blood 109 (5), 2202-2204, 2007
1512007
A monoclonal antibody against an erythrocyte ontogenic antigen identifies fetal and adult erythroid progenitors
P Edelman, G Vinci, JL Villeval, W Vainchenker, A Henri, R Miglierina, ...
1481986
Pathophysiology of thrombocytopenia and anemia in mice lacking transcription factor NF-E2
J Levin, JP Peng, GR Baker, JL Villeval, P Lecine, SA Burstein, ...
Blood, The Journal of the American Society of Hematology 94 (9), 3037-3047, 1999
1281999
Ectopic expression of Delta4 impairs hematopoietic development and leads to lymphoproliferative disease
M Dorsch, G Zheng, D Yowe, P Rao, Y Wang, Q Shen, C Murphy, X Xiong, ...
Blood, The Journal of the American Society of Hematology 100 (6), 2046-2055, 2002
1272002
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