| Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ... Cell Death & Differentiation 25 (3), 486-541, 2018 | 5354 | 2018 |
| Succinate is an inflammatory signal that induces IL-1β through HIF-1α GM Tannahill, AM Curtis, J Adamik, EM Palsson-McDermott, ... Nature 496 (7444), 238-242, 2013 | 3398 | 2013 |
| Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012 L Galluzzi, I Vitale, JM Abrams, ES Alnemri, EH Baehrecke, ... Cell Death & Differentiation 19 (1), 107-120, 2012 | 3131 | 2012 |
| TIGAR, a p53-inducible regulator of glycolysis and apoptosis K Bensaad, A Tsuruta, MA Selak, MNC Vidal, K Nakano, R Bartrons, ... Cell 126 (1), 107-120, 2006 | 2369 | 2006 |
| Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase MA Selak, SM Armour, ED MacKenzie, H Boulahbel, DG Watson, ... Cancer cell 7 (1), 77-85, 2005 | 2310 | 2005 |
| Succinate dehydrogenase supports metabolic repurposing of mitochondria to drive inflammatory macrophages EL Mills, B Kelly, A Logan, ASH Costa, M Varma, CE Bryant, ... Cell 167 (2), 457-470. e13, 2016 | 1657 | 2016 |
| Targeting metabolic transformation for cancer therapy DA Tennant, RV Durán, E Gottlieb Nature reviews cancer 10 (4), 267-277, 2010 | 1273 | 2010 |
| Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells ODK Maddocks, CR Berkers, SM Mason, L Zheng, K Blyth, E Gottlieb, ... Nature 493 (7433), 542-546, 2013 | 953 | 2013 |
| Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer A King, MA Selak, E Gottlieb Oncogene 25 (34), 4675-4682, 2006 | 857 | 2006 |
| mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation M Morita, SP Gravel, V Chenard, K Sikström, L Zheng, T Alain, V Gandin, ... Cell metabolism 18 (5), 698-711, 2013 | 797 | 2013 |
| Mitochondrial membrane potential regulates matrix configuration and cytochrome c release during apoptosis E Gottlieb, SM Armour, MH Harris, CB Thompson Cell Death & Differentiation 10 (6), 709-717, 2003 | 796 | 2003 |
| Mitochondrial tumour suppressors: a genetic and biochemical update E Gottlieb, IPM Tomlinson Nature Reviews Cancer 5 (11), 857-866, 2005 | 777 | 2005 |
| p53 status determines the role of autophagy in pancreatic tumour development MT Rosenfeldt, J O’Prey, JP Morton, C Nixon, G MacKay, A Mrowinska, ... Nature 504 (7479), 296-300, 2013 | 723 | 2013 |
| Glutaminolysis activates Rag-mTORC1 signaling RV Durán, W Oppliger, AM Robitaille, L Heiserich, R Skendaj, E Gottlieb, ... Molecular cell 47 (3), 349-358, 2012 | 720 | 2012 |
| Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress ZT Schug, B Peck, DT Jones, Q Zhang, S Grosskurth, IS Alam, ... Cancer cell 27 (1), 57-71, 2015 | 703 | 2015 |
| Serine is a natural ligand and allosteric activator of pyruvate kinase M2 B Chaneton, P Hillmann, L Zheng, ACL Martin, ODK Maddocks, ... Nature 491 (7424), 458-462, 2012 | 661 | 2012 |
| A key role for mitochondrial gatekeeper pyruvate dehydrogenase in oncogene-induced senescence J Kaplon, L Zheng, K Meissl, B Chaneton, VA Selivanov, G Mackay, ... Nature 498 (7452), 109-112, 2013 | 626 | 2013 |
| A roadmap for interpreting 13C metabolite labeling patterns from cells JM Buescher, MR Antoniewicz, LG Boros, SC Burgess, H Brunengraber, ... Current opinion in biotechnology 34, 189-201, 2015 | 605 | 2015 |
| Predicting selective drug targets in cancer through metabolic networks O Folger, L Jerby, C Frezza, E Gottlieb, E Ruppin, T Shlomi Molecular systems biology 7 (1), 501, 2011 | 587 | 2011 |
| Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase C Frezza, L Zheng, O Folger, KN Rajagopalan, ED MacKenzie, L Jerby, ... Nature 477 (7363), 225-228, 2011 | 542 | 2011 |
