| High-throughput screening for potent and selective inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase J Baldwin, CH Michnoff, NA Malmquist, J White, MG Roth, PK Rathod, ... Journal of Biological Chemistry 280 (23), 21847-21853, 2005 | 253 | 2005 |
| High-throughput screening for potent and selective inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase J Baldwin, CH Michnoff, NA Malmquist, J White, MG Roth, PK Rathod, ... Journal of Biological Chemistry 280 (23), 21847-21853, 2005 | 253 | 2005 |
| Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitors with Potent and Selective Activity against the Malaria Parasite Plasmodium falciparum MA Phillips, R Gujjar, NA Malmquist, J White, F El Mazouni, J Baldwin, ... Journal of medicinal chemistry 51 (12), 3649-3653, 2008 | 245 | 2008 |
| Persistence and activation of malaria hypnozoites in long-term primary hepatocyte cultures L Dembélé, JF Franetich, A Lorthiois, A Gego, AM Zeeman, CHM Kocken, ... Nature medicine 20 (3), 307-312, 2014 | 201 | 2014 |
| Host cell entry by apicomplexa parasites requires actin polymerization in the host cell V Gonzalez, A Combe, V David, NA Malmquist, V Delorme, C Leroy, ... Cell host & microbe 5 (3), 259-272, 2009 | 177 | 2009 |
| Malarial dihydroorotate dehydrogenase: substrate and inhibitor specificity J Baldwin, AM Farajallah, NA Malmquist, PK Rathod, MA Phillips Journal of Biological Chemistry 277 (44), 41827-41834, 2002 | 150 | 2002 |
| Structural plasticity of malaria dihydroorotate dehydrogenase allows selective binding of diverse chemical scaffolds X Deng, R Gujjar, F El Mazouni, W Kaminsky, NA Malmquist, ... Journal of Biological Chemistry 284 (39), 26999-27009, 2009 | 146 | 2009 |
| Small-molecule histone methyltransferase inhibitors display rapid antimalarial activity against all blood stage forms in Plasmodium falciparum NA Malmquist, TA Moss, S Mecheri, A Scherf, MJ Fuchter Proceedings of the National Academy of Sciences 109 (41), 16708-16713, 2012 | 135 | 2012 |
| Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies TL Arakaki, FS Buckner, JR Gillespie, NA Malmquist, MA Phillips, ... Molecular microbiology 68 (1), 37-50, 2008 | 95 | 2008 |
| Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria Q Zhang, TN Siegel, RM Martins, F Wang, J Cao, Q Gao, X Cheng, ... Nature 513 (7518), 431-435, 2014 | 85 | 2014 |
| Analysis of Flavin Oxidation and Electron-Transfer Inhibition in Plasmodium falciparum Dihydroorotate Dehydrogenase NA Malmquist, R Gujjar, PK Rathod, MA Phillips Biochemistry 47 (8), 2466-2475, 2008 | 76 | 2008 |
| NO‐induced relaxation of labouring and non‐labouring human myometrium is not mediated by cyclic GMP ILO Buxton, RA Kaiser, NA Malmquist, S Tichenor British journal of pharmacology 134 (1), 206-214, 2001 | 75 | 2001 |
| Regulation of surface coat exchange by differentiating African trypanosomes AE Gruszynski, FJ van Deursen, MC Albareda, A Best, K Chaudhary, ... Molecular and biochemical parasitology 147 (2), 211-223, 2006 | 70 | 2006 |
| Comprehensive histone phosphorylation analysis and identification of Pf14-3-3 protein as a histone H3 phosphorylation reader in malaria parasites EG Dastidar, K Dzeyk, J Krijgsveld, NA Malmquist, C Doerig, A Scherf, ... PloS one 8 (1), e53179, 2013 | 54 | 2013 |
| Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans NA Malmquist, S Sundriyal, J Caron, P Chen, B Witkowski, D Menard, ... Antimicrobial agents and chemotherapy 59 (2), 950-959, 2015 | 49 | 2015 |
| Plasmodium falciparum PfSET7: enzymatic characterization and cellular localization of a novel protein methyltransferase in sporozoite, liver and erythrocytic stage … PB Chen, S Ding, G Zanghì, V Soulard, PA DiMaggio, MJ Fuchter, ... Scientific reports 6 (1), 21802, 2016 | 40 | 2016 |
| Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH) M Lucas-Hourani, H Munier-Lehmann, F El Mazouni, NA Malmquist, ... Journal of medicinal chemistry 58 (14), 5579-5598, 2015 | 40 | 2015 |
| Development of diaminoquinazoline histone lysine methyltransferase inhibitors as potent blood‐stage antimalarial compounds S Sundriyal, NA Malmquist, J Caron, S Blundell, F Liu, X Chen, ... ChemMedChem 9 (10), 2360-2373, 2014 | 39 | 2014 |
| Secretion of a nucleoside diphosphate kinase (Nm23-H2) by cells from human breast, colon, pancreas and lung tumors. JJ Anzinger, NA Malmquist, J Gould, ILO Buxton Proceedings of the Western Pharmacological Society 44, 61-63, 2001 | 36 | 2001 |
| Histone lysine methyltransferase structure activity relationships that allow for segregation of G9a inhibition and anti-Plasmodium activity S Sundriyal, PB Chen, AS Lubin, GA Lueg, F Li, AJP White, NA Malmquist, ... MedChemComm 8 (5), 1069-1092, 2017 | 28 | 2017 |
