Three-dimensional structure of myosin subfragment-1: a molecular motor I Rayment, WR Rypniewski, K Schmidt-Bäse, R Smith, DR Tomchick, ... Science 261 (5117), 50-58, 1993 | 2637 | 1993 |
A protein catalytic framework with an N-terminal nucleophile is capable of self-activation JA Brannigan, G Dodson, HJ Duggleby, PCE Moody, JL Smith, ... Nature 378 (6555), 416-419, 1995 | 823 | 1995 |
Three-dimensional structure of the complexin/SNARE complex X Chen, DR Tomchick, E Kovrigin, D Araç, M Machius, TC Südhof, J Rizo Neuron 33 (3), 397-409, 2002 | 526 | 2002 |
Structural basis of actin filament nucleation and processive capping by a formin homology 2 domain T Otomo, DR Tomchick, C Otomo, SC Panchal, M Machius, MK Rosen Nature 433 (7025), 488-494, 2005 | 483 | 2005 |
Pivotal role of water in the mechanism of P450BM-3 DC Haines, DR Tomchick, M Machius, JA Peterson Biochemistry 40 (45), 13456-13465, 2001 | 440 | 2001 |
Structural basis for CoREST-dependent demethylation of nucleosomes by the human LSD1 histone demethylase M Yang, CB Gocke, X Luo, D Borek, DR Tomchick, M Machius, ... Molecular cell 23 (3), 377-387, 2006 | 391 | 2006 |
Structure of the photolyase-like domain of cryptochrome 1 from Arabidopsis thaliana CA Brautigam, BS Smith, Z Ma, M Palnitkar, DR Tomchick, M Machius, ... Proceedings of the National Academy of Sciences 101 (33), 12142-12147, 2004 | 361 | 2004 |
A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria MA Phillips, J Lotharius, K Marsh, J White, A Dayan, KL White, ... Science translational medicine 7 (296), 296ra111-296ra111, 2015 | 324 | 2015 |
Artificial ligand binding within the HIF2α PAS-B domain of the HIF2 transcription factor TH Scheuermann, DR Tomchick, M Machius, Y Guo, RK Bruick, ... Proceedings of the National Academy of Sciences 106 (2), 450-455, 2009 | 306 | 2009 |
Structural basis of Rho GTPase-mediated activation of the formin mDia1 T Otomo, C Otomo, DR Tomchick, M Machius, MK Rosen Molecular cell 18 (3), 273-281, 2005 | 284 | 2005 |
Crystal structure of a 12 ANK repeat stack from human ankyrinR P Michaely, DR Tomchick, M Machius, RGW Anderson The EMBO journal, 2002 | 258 | 2002 |
Munc13 C2B domain is an activity-dependent Ca2+ regulator of synaptic exocytosis OH Shin, J Lu, JS Rhee, DR Tomchick, ZP Pang, SM Wojcik, ... Nature structural & molecular biology 17 (3), 280-288, 2010 | 252 | 2010 |
p31comet blocks Mad2 activation through structural mimicry M Yang, B Li, DR Tomchick, M Machius, J Rizo, H Yu, X Luo Cell 131 (4), 744-755, 2007 | 235 | 2007 |
Structure of Cdc42 in a complex with the GTPase‐binding domain of the cell polarity protein, Par6 SM Garrard, CT Capaldo, L Gao, MK Rosen, IG Macara, DR Tomchick The EMBO journal, 2003 | 219 | 2003 |
Structural basis of histone demethylation by LSD1 revealed by suicide inactivation M Yang, JC Culhane, LM Szewczuk, CB Gocke, CA Brautigam, ... Nature structural & molecular biology 14 (6), 535-539, 2007 | 212 | 2007 |
Enzyme structure and dynamics affect hydrogen tunneling: The impact of a remote side chain (I553) in soybean lipoxygenase-1 MP Meyer, DR Tomchick, JP Klinman Proceedings of the National Academy of Sciences 105 (4), 1146-1151, 2008 | 194 | 2008 |
Structural and functional characterization of second-coordination sphere mutants of soybean lipoxygenase-1 DR Tomchick, P Phan, M Cymborowski, W Minor, TR Holman Biochemistry 40 (25), 7509-7517, 2001 | 178 | 2001 |
Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion K Hara, G Zheng, Q Qu, H Liu, Z Ouyang, Z Chen, DR Tomchick, H Yu Nature structural & molecular biology 21 (10), 864-870, 2014 | 177 | 2014 |
Structural and functional analysis of the YAP-binding domain of human TEAD2 W Tian, J Yu, DR Tomchick, D Pan, X Luo Proceedings of the National Academy of Sciences 107 (16), 7293-7298, 2010 | 172 | 2010 |
Structural and energetic mechanisms of cooperative autoinhibition and activation of Vav1 B Yu, IRS Martins, P Li, GK Amarasinghe, J Umetani, ... Cell 140 (2), 246-256, 2010 | 172 | 2010 |