Carolina Borsoi Moraes
Carolina Borsoi Moraes
Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of
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Nitroheterocyclic compounds are more efficacious than CYP51 inhibitors against Trypanosoma cruzi: implications for Chagas disease drug discovery and …
CB Moraes, MA Giardini, H Kim, CH Franco, AM Araujo-Junior, ...
Scientific reports 4, 4703, 2014
Drug discovery for Chagas disease should consider Trypanosoma cruzi strain diversity
B Zingales, MA Miles, CB Moraes, A Luquetti, F Guhl, AG Schijman, ...
Memórias do Instituto Oswaldo Cruz 109, 828-833, 2014
Amazonian plant natural products: perspectives for discovery of new antimalarial drug leads
AM Pohlit, RBS Lima, G Frausin, SCP Lopes, CB Moraes, P Cravo, ...
Molecules 18 (8), 9219-9240, 2013
Current and Future Chemotherapy for Chagas Disease
L Gaspar, C B Moraes, L H Freitas-Junior, S Ferrari, L Costantino, ...
Current medicinal chemistry 22 (37), 4293-4312, 2015
Bacteria from Antarctic environments: diversity and detection of antimicrobial, antiproliferative, and antiparasitic activities
TR Silva, AWF Duarte, MRZ Passarini, ALTG Ruiz, CH Franco, ...
Polar Biology 41, 1505-1519, 2018
Chroman-4-One Derivatives Targeting Pteridine Reductase 1 and Showing Anti-Parasitic Activity
F Di Pisa, G Landi, L Dello Iacono, C Pozzi, C Borsari, S Ferrari, ...
Molecules 22 (3), 426, 2017
An image-based algorithm for precise and accurate high throughput assessment of drug activity against the human parasite Trypanosoma cruzi
S Moon, JL Siqueira-Neto, CB Moraes, G Yang, M Kang, ...
PloS one 9 (2), e87188, 2014
Drug Discovery for Human African Trypanosomiasis Identification of Novel Scaffolds by the Newly Developed HTS SYBR Green Assay for Trypanosoma brucei
J Faria, CB Moraes, R Song, BS Pascoalino, N Lee, JL Siqueira-Neto, ...
Journal of biomolecular screening 20 (1), 70-81, 2015
Hydrocephalus and arthrogryposis in an immunocompetent mouse model of ZIKA teratogeny: A developmental study
J Xavier-Neto, M Carvalho, BS Pascoalino, AC Cardoso, ÂMS Costa, ...
PLoS neglected tropical diseases 11 (2), e0005363, 2017
A comparative study of warheads for design of cysteine protease inhibitors
DG Silva, JFR Ribeiro, D De Vita, L Cianni, CH Franco, LH Freitas-Junior, ...
Bioorganic & medicinal chemistry letters 27 (22), 5031-5035, 2017
Drug Discovery for Chagas Disease: Impact of Different Host Cell Lines on Assay Performance and Hit Compound Selection
CH Franco, LM Alcântara, E Chatelain, L Freitas-Junior, CB Moraes
Tropical medicine and infectious disease 4 (2), 82, 2019
Aryl thiosemicarbazones for the treatment of trypanosomatidic infections
P Linciano, CB Moraes, LM Alcantara, CH Franco, B Pascoalino, ...
European journal of medicinal chemistry 146, 423-434, 2018
Design, synthesis and antitrypanosomal activity of some nitrofurazone 1, 2, 4-triazolic bioisosteric analogues
FT Silva, CH Franco, DC Favaro, LH Freitas-Junior, CB Moraes, ...
European Journal of Medicinal Chemistry 121, 553-560, 2016
Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase (TcTR) and display …
E Uliassi, G Fiorani, RL Krauth-Siegel, C Bergamini, R Fato, G Bianchini, ...
European journal of medicinal chemistry 141, 138-148, 2017
Computer-aided discovery of two novel chalcone-like compounds active and selective against Leishmania infantum
MN Gomes, LM Alcântara, BJ Neves, CC Melo-Filho, LH Freitas-Junior, ...
Bioorganic & Medicinal Chemistry Letters 27 (11), 2459-2464, 2017
An essential nuclear protein in trypanosomes is a component of mRNA transcription/export pathway
M Serpeloni, CB Moraes, JRC Muniz, MCM Motta, ASP Ramos, ...
PLoS One 6 (6), e20730, 2011
Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
P Linciano, A Dawson, I Pöhner, DM Costa, MS Sá, A Cordeiro-da-Silva, ...
ACS omega 2 (9), 5666-5683, 2017
Quantum dots: a new tool for anti-malarial drug assays
MJ Ku, FM Dossin, Y Choi, CB Moraes, J Ryu, R Song, LH Freitas-Junior
Malaria journal 10 (1), 118, 2011
The translational challenge in Chagas disease drug development
JM Kratz, KR Gonçalves, L Romera, CB Moraes, P Bittencourt-Cunha, ...
Memórias do Instituto Oswaldo Cruz 117, 2022
Non-Toxic Dimeric Peptides Derived from the Bothropstoxin-I Are Potent SARS-CoV-2 and Papain-like Protease Inhibitors
MCLC Freire, GD Noske, NV Bitencourt, PRS Sanches, NA Santos-Filho, ...
Molecules 26 (16), 4896, 2021
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