Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer. Cell 174 (3), 758-769, 2018 | 633 | 2018 |
Expressed Pseudogenes in the Transcriptional Landscape of Human Cancers S Kalyana-Sundaram, C Kumar-Sinha, S Shankar, DR Robinson, YM Wu, ... Cell 149 (7), 1622-1634, 2012 | 314 | 2012 |
Analysis of circulating cell-free DNA identifies multi-clonal heterogeneity of BRCA2 reversion mutations associated with resistance to PARP inhibitors FFY Quigley D, Alumkal JJ, Wyatt AW, Kothari V, Foye A, Lloyd P, Aggarwal R ... Cancer Discovery, 2017 | 261 | 2017 |
The long non-coding RNA PCAT-1 promotes prostate cancer cell proliferation through cMyc. FFY Prensner JR, Chen W, Han S, Iyer MK, Cao Q, Kothari V, Evans JR, Knudsen ... Neoplasia 16 (11), 900-908, 2014 | 258 | 2014 |
DNA-PKcs-mediated transcriptional regulation drives prostate cancer progression and metastasis JF Goodwin, V Kothari, JM Drake, S Zhao, E Dylgjeri, JL Dean, ... Cancer cell 28 (1), 97-113, 2015 | 175 | 2015 |
Genomic drivers of poor prognosis and enzalutamide resistance in metastatic castration-resistant prostate cancer WS Chen, R Aggarwal, L Zhang, SG Zhao, GV Thomas, TM Beer, ... European urology 76 (5), 562-571, 2019 | 123 | 2019 |
Maternal embryonic leucine zipper kinase (MELK) as a novel mediator and biomarker of radioresistance in human breast cancer C Speers, SG Zhao, V Kothari, A Santola, M Liu, K Wilder-Romans, ... Clinical Cancer Research 22 (23), 5864-5875, 2016 | 108 | 2016 |
Androgen receptor as a mediator and biomarker of radioresistance in triple-negative breast cancer. FFY Speers C, Zhao SG, Chandler B, Liu M, Wilder-Romans K, Olsen E, Nyati S ... NPJ Breast Cancer. 3 (29), 2017 | 56 | 2017 |
MDM2 inhibition sensitizes prostate cancer cells to androgen ablation and radiotherapy in a p53-dependent manner FY Feng, Y Zhang, V Kothari, JR Evans, WC Jackson, W Chen, ... Neoplasia 18 (4), 213-222, 2016 | 56 | 2016 |
The landscape of prognostic outlier genes in high-risk prostate cancer SG Zhao, JR Evans, V Kothari, G Sun, A Larm, V Mondine, EM Schaeffer, ... Clinical cancer research 22 (7), 1777-1786, 2016 | 54 | 2016 |
Patient-level DNA damage and repair pathway profiles and prognosis after prostatectomy for high-risk prostate cancer JR Evans, SG Zhao, SL Chang, SA Tomlins, N Erho, A Sboner, ... JAMA oncology 2 (4), 471-480, 2016 | 52 | 2016 |
Outlier Kinase Expression by RNA Sequencing as Targets for Precision Therapy. V Kothari, I Wei, S Shankar, S Kalyana-Sundaram, L Wang, LW Ma, ... Cancer discovery, 2013 | 50 | 2013 |
KRAS engages AGO2 to enhance cellular transformation S Shankar, S Pitchiaya, R Malik, V Kothari, Y Hosono, AK Yocum, ... Cell reports 14 (6), 1448-1461, 2016 | 46 | 2016 |
Cellular and Molecular Mechanisms of Accelerated Fracture Healing by COX2 Gene Therapy. Studies in a Mouse Model of Multiple Fractures. KH Lau, V Kothari, A Das, XB Zhang, DJ Baylink Bone, 2013 | 37 | 2013 |
Pleiotropic impact of DNA-PK in cancer and implications for therapeutic strategies E Dylgjeri, C McNair, JF Goodwin, HK Raymon, PA McCue, AA Shafi, ... Clinical Cancer Research 25 (18), 5623-5637, 2019 | 28 | 2019 |
HDAC inhibitor valproic acid enhances tumor cell kill in adenovirus‐HSVtk mediated suicide gene therapy in HNSCC xenograft mouse model V Kothari, G Joshi, S Nama, K Somasundaram, R Mulherkar International journal of cancer 126 (3), 733-742, 2010 | 27 | 2010 |
Inhibition of cyclin D1 by shRNA is associated with enhanced sensitivity to conventional therapies for head and neck squamous cell carcinoma V Kothari, R Mulherkar Anticancer research 32 (1), 121-128, 2012 | 22 | 2012 |
CDKN1B Deletions are Associated with Metastasis in African American Men with Clinically Localized, Surgically Treated Prostate Cancer FA Faisal, S Murali, H Kaur, T Vidotto, LB Guedes, DC Salles, V Kothari, ... Clinical Cancer Research 26 (11), 2595-2602, 2020 | 20 | 2020 |
DNA-dependent protein kinase drives prostate cancer progression through transcriptional regulation of the Wnt signaling pathway V Kothari, JF Goodwin, SG Zhao, JM Drake, Y Yin, SL Chang, JR Evans, ... Clinical Cancer Research 25 (18), 5608-5622, 2019 | 20 | 2019 |
A novel role for DNA-PK in metabolism by regulating glycolysis in castration-resistant prostate cancer E Dylgjeri, V Kothari, AA Shafi, G Semenova, PT Gallagher, YF Guan, ... Clinical Cancer Research 28 (7), 1446-1459, 2022 | 13 | 2022 |