| d‐Serine is a key determinant of glutamate toxicity in amyotrophic lateral sclerosis J Sasabe, T Chiba, M Yamada, K Okamoto, I Nishimoto, M Matsuoka, ... The EMBO journal 26 (18), 4149-4159, 2007 | 311 | 2007 |
| Amyloid-β causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons T Chiba, M Yamada, J Sasabe, K Terashita, M Shimoda, M Matsuoka, ... Molecular psychiatry 14 (2), 206-222, 2009 | 230 | 2009 |
| Targeting the JAK2/STAT3 axis in Alzheimer's disease T Chiba, M Yamada, S Aiso Expert opinion on therapeutic targets 13 (10), 1155-1167, 2009 | 136 | 2009 |
| Involvement of c‐Jun N‐terminal kinase in amyloid precursor protein‐mediated neuronal cell death Y Hashimoto, O Tsuji, T Niikura, Y Yamagishi, M Ishizaka, M Kawasumi, ... Journal of neurochemistry 84 (4), 864-877, 2003 | 128 | 2003 |
| A humanin derivative, S14G‐HN, prevents amyloid‐β‐induced memory impairment in mice H Tajima, M Kawasumi, T Chiba, M Yamada, K Yamashita, M Nawa, ... Journal of neuroscience research 79 (5), 714-723, 2005 | 126 | 2005 |
| Development of a femtomolar-acting humanin derivative named colivelin by attaching activity-dependent neurotrophic factor to its N terminus: characterization of colivelin … T Chiba, M Yamada, Y Hashimoto, M Sato, J Sasabe, Y Kita, K Terashita, ... Journal of Neuroscience 25 (44), 10252-10261, 2005 | 118 | 2005 |
| Two serine residues distinctly regulate the rescue function of Humanin, an inhibiting factor of Alzheimer's disease‐related neurotoxicity: functional potentiation by … K Terashita, Y Hashimoto, T Niikura, H Tajima, Y Yamagishi, M Ishizaka, ... Journal of Neurochemistry 85 (6), 1521-1538, 2003 | 100 | 2003 |
| The cytoplasmic domain of Alzheimer's amyloid-β protein precursor causes sustained apoptosis signal-regulating kinase 1/c-Jun NH2-terminal kinase-mediated neurotoxic signal via … Y Hashimoto, T Niikura, T Chiba, E Tsukamoto, H Kadowaki, H Nishitoh, ... Journal of Pharmacology and Experimental Therapeutics 306 (3), 889-902, 2003 | 85 | 2003 |
| Molecular mechanisms for neuronal cell death by Alzheimer’s amyloid precursor protein-relevant insults M Kawasumi, Y Hashimoto, T Chiba, K Kanekura, Y Yamagishi, ... Neurosignals 11 (5), 236-250, 2002 | 81 | 2002 |
| Implanted cannula-mediated repetitive administration of Aβ25–35 into the mouse cerebral ventricle effectively impairs spatial working memory M Yamada, T Chiba, J Sasabe, M Nawa, H Tajima, T Niikura, K Terashita, ... Behavioural brain research 164 (2), 139-146, 2005 | 80 | 2005 |
| Nasal Colivelin treatment ameliorates memory impairment related to Alzheimer's disease M Yamada, T Chiba, J Sasabe, K Terashita, S Aiso, M Matsuoka Neuropsychopharmacology 33 (8), 2020-2032, 2008 | 77 | 2008 |
| Humanin: after the discovery T Niikura, T Chiba, S Aiso, M Matsuoka, I Nishimoto Molecular Neurobiology 30, 327-340, 2004 | 66 | 2004 |
| Characterization of V642I‐AβPP‐induced cytotoxicity in primary neurons T Niikura, M Yamada, T Chiba, S Aiso, M Matsuoka, I Nishimoto Journal of neuroscience research 77 (1), 54-62, 2004 | 61 | 2004 |
| Targeted introduction of V642I mutation in amyloid precursor protein gene causes functional abnormality resembling early stage of Alzheimer's disease in aged mice M Kawasumi, T Chiba, M Yamada, M Miyamae‐Kaneko, M Matsuoka, ... European Journal of Neuroscience 19 (10), 2826-2838, 2004 | 61 | 2004 |
| Transforming growth factor β2 is a neuronal death-inducing ligand for amyloid-β precursor protein Y Hashimoto, T Chiba, M Yamada, M Nawa, K Kanekura, H Suzuki, ... Molecular and cellular biology, 2005 | 58 | 2005 |
| Neuroprotective effect of activity‐dependent neurotrophic factor against toxicity from familial amyotrophic lateral sclerosis‐linked mutant SOD1 in vitro and in vivo T Chiba, Y Hashimoto, H Tajima, M Yamada, R Kato, T Niikura, ... Journal of neuroscience research 78 (4), 542-552, 2004 | 48 | 2004 |
| Colivelin prolongs survival of an ALS model mouse T Chiba, M Yamada, J Sasabe, K Terashita, S Aiso, M Matsuoka, ... Biochemical and biophysical research communications 343 (3), 793-798, 2006 | 47 | 2006 |
| Neuroprotection against neurodegenerative diseases: development of a novel hybrid neuroprotective peptide Colivelin T Chiba, I Nishimoto, S Aiso, M Matsuoka Molecular neurobiology 35, 55-84, 2007 | 46 | 2007 |
| Expression of the mi R‐302/367 cluster in glioblastoma cells suppresses tumorigenic gene expression patterns and abolishes transformation related phenotypes CM Yang, T Chiba, B Brill, N Delis, V von Manstein, V Vafaizadeh, ... International Journal of Cancer 137 (10), 2296-2309, 2015 | 41 | 2015 |
| Humanin antagonists: mutants that interfere with dimerization inhibit neuroprotection by Humanin Y Hashimoto, K Terashita, T Niikura, Y Yamagishi, M Ishizaka, ... European Journal of Neuroscience 19 (9), 2356-2364, 2004 | 37 | 2004 |
Jumpei SasabeKeio University School of MedicineVerified email at a8.keio.jp
