Adam S. Adler
Adam S. Adler
GigaGen, Inc.
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SIRT6 links histone H3 lysine 9 deacetylation to NF-κB-dependent gene expression and organismal life span
TLA Kawahara, E Michishita, AS Adler, M Damian, E Berber, M Lin, ...
Cell 136 (1), 62-74, 2009
Decoding global gene expression programs in liver cancer by noninvasive imaging
E Segal, CB Sirlin, C Ooi, AS Adler, J Gollub, X Chen, BK Chan, ...
Nature biotechnology 25 (6), 675-680, 2007
Motif module map reveals enforcement of aging by continual NF-κB activity
AS Adler, S Sinha, TLA Kawahara, JY Zhang, E Segal, HY Chang
Genes & development 21 (24), 3244-3257, 2007
Genetic regulators of large-scale transcriptional signatures in cancer
AS Adler, M Lin, H Horlings, DSA Nuyten, MJ van de Vijver, HY Chang
Nature genetics 38 (4), 421-430, 2006
The C2 domain of the Rsp5 ubiquitin ligase binds membrane phosphoinositides and directs ubiquitination of endosomal cargo
R Dunn, DA Klos, AS Adler, L Hicke
The Journal of cell biology 165 (1), 135-144, 2004
An Integrated Genomic Screen Identifies LDHB as an Essential Gene for Triple-Negative Breast CancerLDHB Is a Regulator of Triple-Negative Breast Cancer
ML McCleland, AS Adler, Y Shang, T Hunsaker, T Truong, D Peterson, ...
Cancer research 72 (22), 5812-5823, 2012
The histone demethylase UTX enables RB-dependent cell fate control
JK Wang, MC Tsai, G Poulin, AS Adler, S Chen, H Liu, Y Shi, HY Chang
Genes & development 24 (4), 327-332, 2010
Reversal of aging by NFκB blockade
AS Adler, TLA Kawahara, E Segal, HY Chang
Cell cycle 7 (5), 556-559, 2008
Molecular framework for response to imatinib mesylate in systemic sclerosis
L Chung, DF Fiorentino, MJ BenBarak, AS Adler, MM Mariano, ...
Arthritis & Rheumatism: Official Journal of the American College of…, 2009
CDK8 Maintains Tumor Dedifferentiation and Embryonic Stem Cell PluripotencyCDK8 Regulates Tumor Differentiation and Embryonic Stem Cell Pluripotency
AS Adler, ML McCleland, T Truong, S Lau, Z Modrusan, TM Soukup, ...
Cancer research 72 (8), 2129-2139, 2012
MYC can induce DNA breaks in vivo and in vitro independent of reactive oxygen species
S Ray, KR Atkuri, D Deb-Basu, AS Adler, HY Chang, LA Herzenberg, ...
Cancer research 66 (13), 6598-6605, 2006
Lactate Dehydrogenase B Is Required for the Growth of KRAS-Dependent Lung AdenocarcinomasLDHB Is a Regulator of KRAS-Dependent Lung Cancer
ML McCleland, AS Adler, L Deming, E Cosino, L Lee, EM Blackwood, ...
Clinical Cancer Research 19 (4), 773-784, 2013
An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth
AS Adler, ML McCleland, S Yee, M Yaylaoglu, S Hussain, E Cosino, ...
Genes & development 28 (10), 1068-1084, 2014
Global expression profiling in atopic eczema reveals reciprocal expression of inflammatory and lipid genes
AM Sf, M Tengvall-Linder, HY Chang, AS Adler, CF Wahlgren, ...
PloS one 3 (12), e4017, 2008
The Rsp5 ubiquitin ligase binds to and ubiquitinates members of the yeast CIN85-endophilin complex, Sla1-Rvs167
SD Stamenova, R Dunn, AS Adler, L Hicke
Journal of Biological Chemistry 279 (16), 16017-16025, 2004
A transcriptional program mediating entry into cellular quiescence
H Liu, AS Adler, E Segal, HY Chang
PLoS Genetics 3 (6), e91, 2007
CSN5 isopeptidase activity links COP9 signalosome activation to breast cancer progression
AS Adler, LE Littlepage, M Lin, TLA Kawahara, DJ Wong, Z Werb, ...
Cancer research 68 (2), 506-515, 2008
Monoclonal antibody humanness score and its applications
SH Gao, K Huang, H Tu, AS Adler
BMC biotechnology 13 (1), 1-12, 2013
Revealing targeted therapy for human cancer by gene module maps
DJ Wong, DSA Nuyten, A Regev, M Lin, AS Adler, E Segal, ...
Cancer research 68 (2), 369-378, 2008
Systematic functional characterization of cis-regulatory motifs in human core promoters
S Sinha, AS Adler, Y Field, HY Chang, E Segal
Genome research 18 (3), 477-488, 2008
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