Sledovat
David Sedlák, Ph.D.
David Sedlák, Ph.D.
Institute of Molecular Genetics, Prague
E-mailová adresa ověřena na: img.cas.cz
Název
Citace
Citace
Rok
Probes & drugs portal: an interactive, open data resource for chemical biology
C Skuta, M Popr, T Muller, J Jindrich, M Kahle, D Sedlak, D Svozil, ...
Nature methods 14 (8), 759-760, 2017
622017
Two panels of steroid receptor luciferase reporter cell lines for compound profiling
D Sedlák, A Paguio, P Bartunek
Combinatorial chemistry & high throughput screening 14 (4), 248-266, 2011
552011
Silychristin: Skeletal alterations and biological activities
D Biedermann, M Buchta, V Holečková, D Sedlák, K Valentová, ...
Journal of natural products 79 (12), 3086-3092, 2016
452016
Preparation, preliminary screening of new types of steroid conjugates and their activities on steroid receptors
M Jurášek, P Džubák, D Sedlák, H Dvořáková, M Hajdúch, P Bartůněk, ...
Steroids 78 (3), 356-361, 2013
422013
Synthesis and biochemical characterization of a series of 17α-perfluoroalkylated estradiols as selective ligands for estrogen receptor α
B Eignerová, D Sedlák, M Dračínský, P Bartunek, M Kotora
Journal of medicinal chemistry 53 (19), 6947-6953, 2010
382010
Lipophosphonoxins II: design, synthesis, and properties of novel broad spectrum antibacterial agents
G Seydlová, R Pohl, E Zborníková, M Ehn, O Šimák, N Panova, ...
Journal of Medicinal Chemistry 60 (14), 6098-6118, 2017
332017
c-Myb inhibits myogenic differentiation through repression of MyoD
P Kaspar, P Pajer, D Sedlak, T Tamaoki, M Dvorak
Experimental cell research 309 (2), 419-428, 2005
332005
Structure activity relationship studies on cytotoxicity and the effects on steroid receptors of AB-functionalized cholestanes
L Rarova, J Steigerova, M Kvasnica, P Bartůněk, K Křížová, ...
The Journal of Steroid Biochemistry and Molecular Biology 159, 154-169, 2016
302016
Brassinosteroids inhibit in vitro angiogenesis in human endothelial cells
L Rárová, S Zahler, J Liebl, V Kryštof, D Sedlák, P Bartůněk, L Kohout, ...
Steroids 77 (13), 1502-1509, 2012
302012
PAICS deficiency, a new defect of de novo purine synthesis resulting in multiple congenital anomalies and fatal outcome
A Pelet, V Skopova, U Steuerwald, V Baresova, M Zarhrate, JM Plaza, ...
Human Molecular Genetics 28 (22), 3805-3814, 2019
272019
Synthesis of ferrocenestrone: the first metallocene based steroid analogue
F Hessler, I Císařová, D Sedlák, P Bartůněk, M Kotora
Chemistry-a European Journal 18 (18), 5515, 2012
242012
Trilobolide-steroid hybrids: Synthesis, cytotoxic and antimycobacterial activity
M Jurášek, P Džubák, S Rimpelová, D Sedlák, P Konečný, I Frydrych, ...
Steroids 117, 97-104, 2017
212017
Estradiol dimer inhibits tubulin polymerization and microtubule dynamics
M Jurášek, M Černohorská, J Řehulka, V Spiwok, T Sulimenko, ...
The Journal of Steroid Biochemistry and Molecular Biology 183, 68-79, 2018
202018
Structure–Activity Relationship of para-Carborane Selective Estrogen Receptor β Agonists
D Sedlák, TA Wilson, W Tjarks, HS Radomska, H Wang, JN Kolla, ...
Journal of Medicinal Chemistry 64 (13), 9330-9353, 2021
192021
Synthesis and Evaluation of 17α-Arylestradiols as Ligands for Estrogen Receptor α and β
D Sedlák, P Novák, M Kotora, P Bartunek
Journal of medicinal chemistry 53 (10), 4290-4294, 2010
182010
Development of a high-throughput fluorescence polarization assay to identify novel ligands of glutamate carboxypeptidase II
G Alquicer, D Sedlák, Y Byun, J Pavlíček, M Stathis, C Rojas, B Slusher, ...
Journal of biomolecular screening 17 (8), 1030-1040, 2012
162012
Synergism of BCL-2 family inhibitors facilitates selective elimination of senescent cells
D Rysanek, P Vasicova, JN Kolla, D Sedlak, L Andera, J Bartek, Z Hodny
Aging (Albany NY) 14 (16), 6381, 2022
152022
The novel brassinosteroid analog BR4848 inhibits angiogenesis in human endothelial cells and induces apoptosis in human cancer cells in vitro
L Rárová, D Sedlák, J Oklestkova, J Steigerová, J Liebl, S Zahler, ...
The Journal of Steroid Biochemistry and Molecular Biology 178, 263-271, 2018
142018
Fluorescence-based high-throughput screening of dicer cleavage activity
K Podolska, D Sedlak, P Bartunek, P Svoboda
Journal of biomolecular screening 19 (3), 417-426, 2014
132014
Oxime-based 19-nortestosterone–pheophorbide a conjugate: Bimodal controlled release concept for PDT
V Pavlíčková, M Jurášek, S Rimpelová, K Záruba, D Sedlák, M Šimková, ...
Journal of materials chemistry B 7 (36), 5465-5477, 2019
112019
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Články 1–20