Lori Hazlehurst
Lori Hazlehurst
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Cell adhesion mediated drug resistance (CAM-DR): role of integrins and resistance to apoptosis in human myeloma cell lines
JS Damiano, AE Cress, LA Hazlehurst, AA Shtil, WS Dalton
Blood, the Journal of the American Society of Hematology 93 (5), 1658-1667, 1999
The bone marrow microenvironment as a tumor sanctuary and contributor to drug resistance
MB Meads, LA Hazlehurst, WS Dalton
Clinical Cancer Research 14 (9), 2519-2526, 2008
Adhesion to fibronectin via β1 integrins regulates p27kip1 levels and contributes to cell adhesion mediated drug resistance (CAM-DR)
LA Hazlehurst, JS Damiano, I Buyuksal, WJ Pledger, WS Dalton
Oncogene 19 (38), 4319-4327, 2000
Role of the tumor microenvironment in mediating de novo resistance to drugs and physiological mediators of cell death
LA Hazlehurst, TH Landowski, WS Dalton
Oncogene 22 (47), 7396-7402, 2003
β1 integrin adhesion enhances IL-6–mediated STAT3 signaling in myeloma cells: implications for microenvironment influence on tumor survival and proliferation
KH Shain, DN Yarde, MB Meads, M Huang, R Jove, LA Hazlehurst, ...
Cancer research 69 (3), 1009-1015, 2009
ABCG2 expression, function, and promoter methylation in human multiple myeloma
JG Turner, JL Gump, C Zhang, JM Cook, D Marchion, L Hazlehurst, ...
Blood 108 (12), 3881-3889, 2006
Cell adhesion-mediated drug resistance (CAM-DR) protects the K562 chronic myelogenous leukemia cell line from apoptosis induced by BCR/ABL inhibition, cytotoxic drugs, and γ …
JS Damiano, LA Hazlehurst, WS Dalton
Leukemia 15 (8), 1232-1239, 2001
Mechanisms associated with cell adhesion mediated drug resistance (CAM-DR) in hematopoietic malignancies
LA Hazlehurst, WS Dalton
Cancer and Metastasis Reviews 20, 43-50, 2001
Stat3 contributes to resistance toward BCR-ABL inhibitors in a bone marrow microenvironment model of drug resistance
NN Bewry, RR Nair, MF Emmons, D Boulware, J Pinilla-Ibarz, ...
Molecular cancer therapeutics 7 (10), 3169-3175, 2008
Reduction in drug-induced DNA double-strand breaks associated with β1 integrin–mediated adhesion correlates with drug resistance in U937 cells
LA Hazlehurst, N Valkov, L Wisner, JA Storey, D Boulware, DM Sullivan, ...
Blood, The Journal of the American Society of Hematology 98 (6), 1897-1903, 2001
Multiple mechanisms confer drug resistance to mitoxantrone in the human 8226 myeloma cell line
LA Hazlehurst, NE Foley, MC Gleason-Guzman, MP Hacker, AE Cress, ...
Cancer research 59 (5), 1021-1028, 1999
Genotypic and phenotypic comparisons of de novo and acquired melphalan resistance in an isogenic multiple myeloma cell line model
LA Hazlehurst, SA Enkemann, CA Beam, RF Argilagos, J Painter, ...
Cancer research 63 (22), 7900-7906, 2003
The FA/BRCA pathway is involved in melphalan-induced DNA interstrand cross-link repair and accounts for melphalan resistance in multiple myeloma cells
Q Chen, PC Van der Sluis, D Boulware, LA Hazlehurst, WS Dalton
Blood 106 (2), 698-705, 2005
Pharmacology: principles and practice
M Hacker, WS Messer, KA Bachmann
Academic Press, 2009
Proteomic contributions to personalized cancer care
JM Koomen, EB Haura, G Bepler, R Sutphen, ER Remily-Wood, ...
Molecular & Cellular Proteomics 7 (10), 1780-1794, 2008
Cell adhesion induces p27Kip1-associated cell-cycle arrest through down-regulation of the SCFSkp2 ubiquitin ligase pathway in mantle-cell and other non …
T Lwin, LA Hazlehurst, S Dessureault, R Lai, W Bai, E Sotomayor, ...
Blood, The Journal of the American Society of Hematology 110 (5), 1631-1638, 2007
Targeting the Fanconi anemia/BRCA pathway circumvents drug resistance in multiple myeloma
DN Yarde, V Oliveira, L Mathews, X Wang, A Villagra, D Boulware, ...
Cancer research 69 (24), 9367-9375, 2009
β1 integrin mediated adhesion increases Bim protein degradation and contributes to drug resistance in leukaemia cells
LA Hazlehurst, RF Argilagos, WS Dalton
British journal of haematology 136 (2), 269-275, 2007
Bone marrow stromal cells prevent apoptosis of lymphoma cells by upregulation of anti-apoptotic proteins associated with activation of NF-κB (RelB/p52) in non-Hodgkin's …
T Lwin, LA Hazlehurst, Z Li, S Dessureault, E Sotomayor, LC Moscinski, ...
Leukemia 21 (7), 1521-1531, 2007
Cell adhesion to fibronectin (CAM-DR) influences acquired mitoxantrone resistance in U937 cells
LA Hazlehurst, RF Argilagos, M Emmons, D Boulware, CA Beam, ...
Cancer research 66 (4), 2338-2345, 2006
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