Kayvon Pedram
Kayvon Pedram
Group Leader, HHMI Janelia
Verified email at
Cited by
Cited by
Lysosome-targeting chimaeras for degradation of extracellular proteins
SM Banik, K Pedram, S Wisnovsky, G Ahn, NM Riley, CR Bertozzi
Nature 584 (7820), 291-297, 2020
Spatially resolved proteomic mapping in living cells with the engineered peroxidase APEX2
V Hung, ND Udeshi, SS Lam, KH Loh, KJ Cox, K Pedram, SA Carr, ...
Nature Protocols 11 (3), 456-75, 2016
Small RNAs are modified with N-glycans and displayed on the surface of living cells
RA Flynn, K Pedram, SA Malaker, PJ Batista, BAH Smith, AG Johnson, ...
Cell 184 (12), 3109-3124. e22, 2021
Physical Principles of Membrane Shape Regulation by the Glycocalyx
CR Shurer*, JCH Kuo*, LDM Roberts*, JG Gandhi, MJ Colville, TA Enoki, ...
Cell 177 (7), 1757-1770, 2019
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
SA Malaker*, K Pedram*, MJ Ferracane, BA Bensing, V Krishnan, C Pett, ...
Proceedings of the National Academy of Sciences 116 (15), 7278–7287, 2019
Antibodies to biotin enable large-scale detection of biotinylation sites on proteins
ND Udeshi, K Pedram, T Svinkina, S Fereshetian, SA Myers, O Aygun, ...
Nature Methods 14 (12), 1167–1170, 2017
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
S Wisnovsky, L Möckl, SA Malaker, K Pedram, GT Hess, NM Riley, ...
Proceedings of the National Academy of Sciences 118 (5), e2015024118, 2021
An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins
DJ Shon, SA Malaker, K Pedram, E Yang, V Krishnan, O Dorigo, ...
Proceedings of the National Academy of Sciences 117 (35), 21299-21307, 2020
Quantitative super-resolution microscopy of the mammalian glycocalyx
L Möckl*, K Pedram*, AR Roy, V Krishnan, AK Gustavsson, O Dorigo, ...
Developmental Cell 50 (1), 57-72, 2019
Bump-and-hole engineering identifies specific substrates of glycosyltransferases in living cells
B Schumann, SA Malaker, SP Wisnovsky, MF Debets, AJ Agbay, ...
Molecular cell 78 (5), 824-834. e15, 2020
A bulky glycocalyx fosters metastasis formation by promoting G1 cell cycle progression
EC Woods, FB Kai, JM Barnes, K Pedram, MW Pickup, MJ Hollander, ...
eLife 6, e25752, 2017
Revealing the human mucinome
SA Malaker*, NM Riley*, DJ Shon, K Pedram, V Krishnan, O Dorigo, ...
Nature communications 13 (1), 1-13, 2022
An acquired and endogenous glycocalyx forms a bidirectional “don’t eat” and “don’t eat me” barrier to phagocytosis
PRC Imbert, A Saric, K Pedram, CR Bertozzi, S Grinstein, SA Freeman
Current Biology 31 (1), 77-89. e5, 2021
Pediatric epilepsy surgery: long-term 5-year seizure remission and medication use
JS Hauptman, K Pedram, CA Sison, R Sankar, N Salamon, HV Vinters, ...
Neurosurgery 71 (5), 985-993, 2012
Design of a mucin-selective protease for targeted degradation of cancer-associated mucins
K Pedram*, DJ Shon*, GS Tender*, NR Mantuano, JJ Northey, KJ Metcalf, ...
Nature Biotechnology, 1-11, 2023
Membrane curvature regulates the spatial distribution of bulky glycoproteins
CH Lu, K Pedram, CT Tsai, T Jones IV, X Li, ML Nakamoto, CR Bertozzi, ...
Nature Communications 13 (1), 3093, 2022
Small molecule inhibitors of mammalian glycosylation
K Almahayni, M Spiekermann, A Fiore, G Yu, K Pedram†, L Möckl†
Matrix Biology Plus, 100108, 2022
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
K Pedram, NN Laqtom, DJ Shon, A Di Spiezio, NM Riley, P Saftig, ...
Proceedings of the National Academy of Sciences 119 (39), e2117105119, 2022
Imaging the extracellular matrix in live tissues and organisms with a glycan-binding fluorophore
A Fiore, G Yu, JJ Northey, R Patel, TA Ravenscroft, R Ikegami, W Kolkman, ...
bioRxiv, 2024
Expansion of in vitro Toxoplasma gondii cysts using enzymatically enhanced ultrastructure expansion microscopy
K Bondarenko, F Limoge, K Pedram, M Gissot, JC Young
bioRxiv, 2024.04. 24.590991, 2024
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Articles 1–20