Tumour acidosis: from the passenger to the driver's seat C Corbet, O Feron Nature Reviews Cancer 17 (10), 577-593, 2017 | 771 | 2017 |
Acidosis drives the reprogramming of fatty acid metabolism in cancer cells through changes in mitochondrial and histone acetylation C Corbet, A Pinto, R Martherus, JPS de Jesus, F Polet, O Feron Cell metabolism 24 (2), 311-323, 2016 | 274 | 2016 |
Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects E Dierge, E Debock, C Guilbaud, C Corbet, E Mignolet, L Mignard, ... Cell metabolism 33 (8), 1701-1715. e5, 2021 | 231 | 2021 |
TGFβ2-induced formation of lipid droplets supports acidosis-driven EMT and the metastatic spreading of cancer cells C Corbet, E Bastien, JP Santiago de Jesus, E Dierge, R Martherus, ... Nature communications 11 (1), 454, 2020 | 204 | 2020 |
Cancer cell metabolism and mitochondria: Nutrient plasticity for TCA cycle fueling C Corbet, O Feron Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1868 (1), 7-15, 2017 | 173 | 2017 |
Interruption of lactate uptake by inhibiting mitochondrial pyruvate transport unravels direct antitumor and radiosensitizing effects C Corbet, E Bastien, N Draoui, B Doix, L Mignion, BF Jordan, A Marchand, ... Nature communications 9 (1), 1208, 2018 | 152 | 2018 |
The SIRT1/HIF2α axis drives reductive glutamine metabolism under chronic acidosis and alters tumor response to therapy C Corbet, N Draoui, F Polet, A Pinto, X Drozak, O Riant, O Feron Cancer research 74 (19), 5507-5519, 2014 | 151 | 2014 |
Emerging roles of lipid metabolism in cancer progression C Corbet, O Feron Current Opinion in Clinical Nutrition & Metabolic Care 20 (4), 254-260, 2017 | 115 | 2017 |
Delivery of siRNA targeting tumor metabolism using non-covalent PEGylated chitosan nanoparticles: Identification of an optimal combination of ligand structure, linker and … C Corbet, H Ragelle, V Pourcelle, K Vanvarenberg, J Marchand-Brynaert, ... Journal of Controlled Release 223, 53-63, 2016 | 100 | 2016 |
Pro-nerve growth factor induces autocrine stimulation of breast cancer cell invasion through tropomyosin-related kinase A (TrkA) and sortilin protein Y Demont, C Corbet, A Page, Y Ataman-Önal, G Choquet-Kastylevsky, ... Journal of Biological Chemistry 287 (3), 1923-1931, 2012 | 92 | 2012 |
A ferrocenyl derivative of hydroxytamoxifen elicits an estrogen receptor-independent mechanism of action in breast cancer cell lines A Vessières, C Corbet, JM Heldt, N Lories, N Jouy, I Laïos, G Leclercq, ... Journal of inorganic biochemistry 104 (5), 503-511, 2010 | 85 | 2010 |
Auranofin radiosensitizes tumor cells through targeting thioredoxin reductase and resulting overproduction of reactive oxygen species H Wang, S Bouzakoura, S De Mey, H Jiang, K Law, I Dufait, C Corbet, ... Oncotarget 8 (22), 35728, 2017 | 72 | 2017 |
Metabolic and mind shifts: from glucose to glutamine and acetate addictions in cancer C Corbet, O Feron Current Opinion in Clinical Nutrition & Metabolic Care 18 (4), 346-353, 2015 | 70 | 2015 |
Reducing the serine availability complements the inhibition of the glutamine metabolism to block leukemia cell growth F Polet, C Corbet, A Pinto, LI Rubio, R Martherus, V Bol, X Drozak, ... Oncotarget 7 (2), 1765, 2016 | 62 | 2016 |
Piperlongumine increases sensitivity of colorectal cancer cells to radiation: Involvement of ROS production via dual inhibition of glutathione and thioredoxin systems H Wang, H Jiang, C Corbet, S de Mey, K Law, T Gevaert, O Feron, ... Cancer letters 450, 42-52, 2019 | 61 | 2019 |
α-Ketothioamide derivatives: a promising tool to interrogate phosphoglycerate dehydrogenase (PHGDH) S Ravez, C Corbet, Q Spillier, A Dutu, AD Robin, E Mullarky, LC Cantley, ... Journal of medicinal chemistry 60 (4), 1591-1597, 2017 | 57 | 2017 |
Therapeutic targeting of cancer stem cells: integrating and exploiting the acidic niche C Vander Linden, C Corbet Frontiers in Oncology 9, 159, 2019 | 54 | 2019 |
The in vivo performance of ferrocenyl tamoxifen lipid nanocapsules in xenografted triple negative breast cancer AL Lainé, E Adriaenssens, A Vessières, G Jaouen, C Corbet, ... Biomaterials 34 (28), 6949-6956, 2013 | 54 | 2013 |
Anti-alcohol abuse drug disulfiram inhibits human PHGDH via disruption of its active tetrameric form through a specific cysteine oxidation Q Spillier, D Vertommen, S Ravez, R Marteau, Q Thémans, C Corbet, ... Scientific reports 9 (1), 4737, 2019 | 52 | 2019 |
Impact of cancer metabolism on therapy resistance–clinical implications AC Gonçalves, E Richiardone, J Jorge, B Polónia, CPR Xavier, ... Drug Resistance Updates 59, 100797, 2021 | 51 | 2021 |