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Cyril Corbet
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Tumour acidosis: from the passenger to the driver's seat
C Corbet, O Feron
Nature Reviews Cancer 17 (10), 577-593, 2017
7712017
Acidosis drives the reprogramming of fatty acid metabolism in cancer cells through changes in mitochondrial and histone acetylation
C Corbet, A Pinto, R Martherus, JPS de Jesus, F Polet, O Feron
Cell metabolism 24 (2), 311-323, 2016
2742016
Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects
E Dierge, E Debock, C Guilbaud, C Corbet, E Mignolet, L Mignard, ...
Cell metabolism 33 (8), 1701-1715. e5, 2021
2312021
TGFβ2-induced formation of lipid droplets supports acidosis-driven EMT and the metastatic spreading of cancer cells
C Corbet, E Bastien, JP Santiago de Jesus, E Dierge, R Martherus, ...
Nature communications 11 (1), 454, 2020
2042020
Cancer cell metabolism and mitochondria: Nutrient plasticity for TCA cycle fueling
C Corbet, O Feron
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1868 (1), 7-15, 2017
1732017
Interruption of lactate uptake by inhibiting mitochondrial pyruvate transport unravels direct antitumor and radiosensitizing effects
C Corbet, E Bastien, N Draoui, B Doix, L Mignion, BF Jordan, A Marchand, ...
Nature communications 9 (1), 1208, 2018
1522018
The SIRT1/HIF2α axis drives reductive glutamine metabolism under chronic acidosis and alters tumor response to therapy
C Corbet, N Draoui, F Polet, A Pinto, X Drozak, O Riant, O Feron
Cancer research 74 (19), 5507-5519, 2014
1512014
Emerging roles of lipid metabolism in cancer progression
C Corbet, O Feron
Current Opinion in Clinical Nutrition & Metabolic Care 20 (4), 254-260, 2017
1152017
Delivery of siRNA targeting tumor metabolism using non-covalent PEGylated chitosan nanoparticles: Identification of an optimal combination of ligand structure, linker and …
C Corbet, H Ragelle, V Pourcelle, K Vanvarenberg, J Marchand-Brynaert, ...
Journal of Controlled Release 223, 53-63, 2016
1002016
Pro-nerve growth factor induces autocrine stimulation of breast cancer cell invasion through tropomyosin-related kinase A (TrkA) and sortilin protein
Y Demont, C Corbet, A Page, Y Ataman-Önal, G Choquet-Kastylevsky, ...
Journal of Biological Chemistry 287 (3), 1923-1931, 2012
922012
A ferrocenyl derivative of hydroxytamoxifen elicits an estrogen receptor-independent mechanism of action in breast cancer cell lines
A Vessières, C Corbet, JM Heldt, N Lories, N Jouy, I Laïos, G Leclercq, ...
Journal of inorganic biochemistry 104 (5), 503-511, 2010
852010
Auranofin radiosensitizes tumor cells through targeting thioredoxin reductase and resulting overproduction of reactive oxygen species
H Wang, S Bouzakoura, S De Mey, H Jiang, K Law, I Dufait, C Corbet, ...
Oncotarget 8 (22), 35728, 2017
722017
Metabolic and mind shifts: from glucose to glutamine and acetate addictions in cancer
C Corbet, O Feron
Current Opinion in Clinical Nutrition & Metabolic Care 18 (4), 346-353, 2015
702015
Reducing the serine availability complements the inhibition of the glutamine metabolism to block leukemia cell growth
F Polet, C Corbet, A Pinto, LI Rubio, R Martherus, V Bol, X Drozak, ...
Oncotarget 7 (2), 1765, 2016
622016
Piperlongumine increases sensitivity of colorectal cancer cells to radiation: Involvement of ROS production via dual inhibition of glutathione and thioredoxin systems
H Wang, H Jiang, C Corbet, S de Mey, K Law, T Gevaert, O Feron, ...
Cancer letters 450, 42-52, 2019
612019
α-Ketothioamide derivatives: a promising tool to interrogate phosphoglycerate dehydrogenase (PHGDH)
S Ravez, C Corbet, Q Spillier, A Dutu, AD Robin, E Mullarky, LC Cantley, ...
Journal of medicinal chemistry 60 (4), 1591-1597, 2017
572017
Therapeutic targeting of cancer stem cells: integrating and exploiting the acidic niche
C Vander Linden, C Corbet
Frontiers in Oncology 9, 159, 2019
542019
The in vivo performance of ferrocenyl tamoxifen lipid nanocapsules in xenografted triple negative breast cancer
AL Lainé, E Adriaenssens, A Vessières, G Jaouen, C Corbet, ...
Biomaterials 34 (28), 6949-6956, 2013
542013
Anti-alcohol abuse drug disulfiram inhibits human PHGDH via disruption of its active tetrameric form through a specific cysteine oxidation
Q Spillier, D Vertommen, S Ravez, R Marteau, Q Thémans, C Corbet, ...
Scientific reports 9 (1), 4737, 2019
522019
Impact of cancer metabolism on therapy resistance–clinical implications
AC Gonçalves, E Richiardone, J Jorge, B Polónia, CPR Xavier, ...
Drug Resistance Updates 59, 100797, 2021
512021
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