Current mathematical models for cancer drug discovery L Carrara, SM Lavezzi, E Borella, G De Nicolao, P Magni, I Poggesi Expert opinion on drug discovery 12 (8), 785-799, 2017 | 27 | 2017 |
Model description language (MDL): a standard for modeling and simulation MK Smith, SL Moodie, R Bizzotto, E Blaudez, E Borella, L Carrara, ... CPT: pharmacometrics & systems pharmacology 6 (10), 647, 2017 | 12 | 2017 |
Modeling tumor growth inhibition and toxicity outcome after administration of anticancer agents in xenograft mice: a dynamic energy budget (DEB) approach N Terranova, EM Tosca, E Borella, E Pesenti, M Rocchetti, P Magni Journal of theoretical biology 450, 1-14, 2018 | 11 | 2018 |
Mathematical modeling of efficacy and safety for anticancer drugs clinical development SM Lavezzi, E Borella, L Carrara, G De Nicolao, P Magni, I Poggesi Expert Opinion on Drug Discovery 13 (1), 5-21, 2018 | 9 | 2018 |
Model‐based prediction of effective target exposure for MEN1611 in combination with trastuzumab in HER2‐positive advanced or metastatic breast cancer patients EM Tosca, E Borella, C Piana, S Bouchene, G Merlino, A Fiascarelli, ... CPT: Pharmacometrics & Systems Pharmacology 12 (11), 1626-1639, 2023 | 7 | 2023 |
Use of prior knowledge and extrapolation in paediatric drug development: A case study with deferasirox E Borella, S Oosterholt, P Magni, O Della Pasqua European Journal of Pharmaceutical Sciences 136, 104931, 2019 | 5 | 2019 |
Complex Bayesian modeling workflows encoding and execution made easy with a novel WinBUGS Plugin of the drug disease model resources interoperability framework C Larizza, E Borella, L Pasotti, P Tartaglione, M Smith, S Moodie, P Magni CPT: Pharmacometrics & Systems Pharmacology 7 (5), 298-308, 2018 | 5 | 2018 |
Characterisation of individual ferritin response in patients receiving chelation therapy E Borella, S Oosterholt, P Magni, O Della Pasqua British journal of clinical pharmacology 88 (8), 3683-3694, 2022 | 4 | 2022 |
Prediction of the effect of renal impairment on the pharmacokinetics of new drugs E Borella, I Poggesi, P Magni Clinical Pharmacokinetics 57, 505-514, 2018 | 3 | 2018 |
Evaluation of software tools for Bayesian estimation on population models with count and continuous data E Borella, L Carrara, S Lavezzi, E Mezzalana, L Pasotti, G DE NICOLAO, ... Proceedings of the 2015 PAGE meeting, June, 2-5, 2015 | 2 | 2015 |
Mathematical modeling of growth and death dynamics of mouse embryonic stem cells irradiated with γ-rays N Terranova, P Rebuzzini, G Mazzini, E Borella, CA Redi, M Zuccotti, ... Journal of Theoretical Biology 363, 374-380, 2014 | 2 | 2014 |
Prospective Evaluation of a Model-Based approach to select Phase 1 Dosing Regimen for MEN1309/OBT076, a novel antibody drug conjugate (ADC) targeting Ly75 antigen for the … E Borella, P Mazzei, C Piana, A Tagliavini, P Magni, S Buontempo, ... PAGE 28, 2019 | 1 | 2019 |
PKPD modelling of MEN1611 anti-tumor effect in xenograft models to predict efficacy threshold concentrations in HER2-positive advanced or metastatic breast cancer patient … EM Tosca, E Borella, C Piana, C Fornari, R Bartolucci, P Mazzei, ... PAGE, 9657-9657, 2021 | | 2021 |
Identification of a Pharmacodynamic Biomarker for SEL24/MEN1703, a First-in-Class Dual PIM/FLT3 Kinase Inhibitor for Acute Myeloid Leukemia, and Its Implementation in the First … A Tomirotti, G Merlino, A Fiascarelli, S Baldini, A Tagliavini, E Borella, ... Blood 134, 5087, 2019 | | 2019 |
BAYESIAN METHODS AND TOOLS TO INTEGRATE PRIOR KNOWLEDGE IN THE DESIGN AND ANALYSIS OF PEDIATRIC CLINICAL TRIALS: A CASE STUDY ON BETA-THALASSEMIA, A RARE DISEASE E Borella Università degli studi di Pavia, 2018 | | 2018 |
Evaluation of software tools for Bayesian estimation on population models: an update based on current software versions R Bartolucci, SM Lavezzi, EM Tosca, N Melillo, S Grandoni, E Borella, ... PAGE 27, 2018 | | 2018 |
Prediction of ferritin response to chelation in patients affected by transfusion-dependent haemoglobinopathies O Della Pasqua, E Borella, S Oosterholt, P Magni Proceedings for Annual Meeting of The Japanese Pharmacological Society …, 2018 | | 2018 |
Evaluation of software tools for Bayesian estimation on population models: an update based on current software versions PM Roberta Bartolucci, Silvia Maria Lavezzi, Elena Maria Tosca, Nicola ... PAGE 27 (2018), www.page-meeting.org/?abstract=8690, 2018 | | 2018 |
Execution of complex Bayesian workflows with the DDMoRe Interoperability Framework: a case study in the diabetes area C Larizza, E Borella, L Pasotti, P Tartaglione, M Smith, S Moodie, P Magni PAGE 26, 7188-7188, 2017 | | 2017 |
Paediatric trial design optimization using prior knowledge in combination with modelling & simulations E Borella, S Oosterholt, P Magni, O Della Pasqua, LSS Session PAGE 26, 7180-7180, 2017 | | 2017 |