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YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs IA Roundtree, GZ Luo, Z Zhang, X Wang, T Zhou, Y Cui, J Sha, X Huang, ... elife 6, e31311, 2017 | 968 | 2017 |
Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects B Shen, W Zhang, J Zhang, J Zhou, J Wang, L Chen, L Wang, A Hodgkins, ... Nature methods 11 (4), 399-402, 2014 | 963 | 2014 |
Generation of gene-modified mice via Cas9/RNA-mediated gene targeting B Shen, J Zhang, H Wu, J Wang, K Ma, Z Li, X Zhang, P Zhang, X Huang Cell research 23 (5), 720-723, 2013 | 823 | 2013 |
Programming and inheritance of parental DNA methylomes in mammals L Wang, J Zhang, J Duan, X Gao, W Zhu, X Lu, L Yang, J Zhang, G Li, ... Cell 157 (4), 979-991, 2014 | 559 | 2014 |
Sperm, but not oocyte, DNA methylome is inherited by zebrafish early embryos L Jiang, J Zhang, JJ Wang, L Wang, L Zhang, G Li, X Yang, X Ma, X Sun, ... Cell 153 (4), 773-784, 2013 | 507 | 2013 |
3D chromatin structures of mature gametes and structural reprogramming during mammalian embryogenesis Y Ke, Y Xu, X Chen, S Feng, Z Liu, Y Sun, X Yao, F Li, W Zhu, L Gao, ... Cell 170 (2), 367-381. e20, 2017 | 456 | 2017 |
Base editing with a Cpf1–cytidine deaminase fusion X Li, Y Wang, Y Liu, B Yang, X Wang, J Wei, Z Lu, Y Zhang, J Wu, ... Nature biotechnology 36 (4), 324-327, 2018 | 439 | 2018 |
sgRNAcas9: a software package for designing CRISPR sgRNA and evaluating potential off-target cleavage sites S Xie, B Shen, C Zhang, X Huang, Y Zhang PloS one 9 (6), e100448, 2014 | 408 | 2014 |
m6A facilitates hippocampus-dependent learning and memory through YTHDF1 H Shi, X Zhang, YL Weng, Z Lu, Y Liu, Z Lu, J Li, P Hao, Y Zhang, F Zhang, ... Nature 563 (7730), 249-253, 2018 | 390 | 2018 |
CRISPR-Cas9 mediated efficient PD-1 disruption on human primary T cells from cancer patients S Su, B Hu, J Shao, B Shen, J Du, Y Du, J Zhou, L Yu, L Zhang, F Chen, ... Scientific reports 6 (1), 20070, 2016 | 345 | 2016 |
Genome modification by CRISPR/Cas9 Y Ma, L Zhang, X Huang The FEBS journal 281 (23), 5186-5193, 2014 | 295 | 2014 |
Opposing roles for the lncRNA haunt and its genomic locus in regulating HOXA gene activation during embryonic stem cell differentiation Y Yin, P Yan, J Lu, G Song, Y Zhu, Z Li, Y Zhao, B Shen, X Huang, H Zhu, ... Cell stem cell 16 (5), 504-516, 2015 | 290 | 2015 |
Osteopontin mediates glioblastoma-associated macrophage infiltration and is a potential therapeutic target J Wei, A Marisetty, B Schrand, K Gabrusiewicz, Y Hashimoto, M Ott, ... The Journal of clinical investigation 129 (1), 137-149, 2019 | 271 | 2019 |
YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma J Hou, H Zhang, J Liu, Z Zhao, J Wang, Z Lu, B Hu, J Zhou, Z Zhao, ... Molecular cancer 18, 1-17, 2019 | 244 | 2019 |
TP53 loss creates therapeutic vulnerability in colorectal cancer Y Liu, X Zhang, C Han, G Wan, X Huang, C Ivan, D Jiang, ... Nature 520 (7549), 697-701, 2015 | 242 | 2015 |
Efficient base editing in methylated regions with a human APOBEC3A-Cas9 fusion X Wang, J Li, Y Wang, B Yang, J Wei, J Wu, R Wang, X Huang, J Chen, ... Nature biotechnology 36 (10), 946-949, 2018 | 237 | 2018 |
Generating rats with conditional alleles using CRISPR/Cas9 Y Ma, X Zhang, B Shen, Y Lu, W Chen, J Ma, L Bai, X Huang, L Zhang Cell research 24 (1), 122-125, 2014 | 227 | 2014 |
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Generation of gene-modified goats targeting MSTN and FGF5 via zygote injection of CRISPR/Cas9 system X Wang, H Yu, A Lei, J Zhou, W Zeng, H Zhu, Z Dong, Y Niu, B Shi, B Cai, ... Scientific reports 5 (1), 13878, 2015 | 209 | 2015 |