Cyclin E and Cdk2 Control GLD-1, the Mitosis/Meiosis Decision, and Germline Stem Cells in Caenorhabditis elegans J Jeong, JM Verheyden, J Kimble PLoS genetics 7 (3), e1001348, 2011 | 75 | 2011 |
MLL leukemia induction by genome editing of human CD34+ hematopoietic cells C Buechele, EH Breese, D Schneidawind, CH Lin, J Jeong, ... Blood, The Journal of the American Society of Hematology 126 (14), 1683-1694, 2015 | 66 | 2015 |
miRNA-mediated TUSC3 deficiency enhances UPR and ERAD to promote metastatic potential of NSCLC YJ Jeon, T Kim, D Park, GJ Nuovo, S Rhee, P Joshi, BK Lee, J Jeong, ... Nature Communications 9 (1), 5110, 2018 | 39 | 2018 |
High-efficiency CRISPR induction of t (9; 11) chromosomal translocations and acute leukemias in human blood stem cells J Jeong, A Jager, P Domizi, M Pavel-Dinu, L Gojenola, M Iwasaki, ... Blood advances 3 (19), 2825-2835, 2019 | 36 | 2019 |
MLL leukemia induction by t (9; 11) chromosomal translocation in human hematopoietic stem cells using genome editing C Schneidawind, J Jeong, D Schneidawind, IS Kim, J Duque-Afonso, ... Blood Advances 2 (8), 832-845, 2018 | 36 | 2018 |
SETDB2 links E2A-PBX1 to cell-cycle dysregulation in acute leukemia through CDKN2C repression CH Lin, SHK Wong, JH Kurzer, C Schneidawind, MC Wei, ... Cell reports 23 (4), 1166-1177, 2018 | 27 | 2018 |
MAT2A as Key Regulator and Therapeutic Target in MLLr Leukemogenesis KA Secker, B Bloechl, H Keppeler, S Duerr-Stoerzer, H Schmid, ... Cancers 12 (5), 1342, 2020 | 19 | 2020 |
Only hematopoietic stem and progenitor cells from cord blood are susceptible to malignant transformation by MLL-AF4 translocations KA Secker, L Bruns, H Keppeler, J Jeong, T Hentrich, ... Cancers 12 (6), 1487, 2020 | 17 | 2020 |
CBP Modulates Sensitivity to Dasatinib in Pre-BCR+ Acute Lymphoblastic Leukemia J Duque-Afonso, CH Lin, K Han, DW Morgens, EE Jeng, Z Weng, J Jeong, ... Cancer research 78 (22), 6497-6508, 2018 | 12 | 2018 |
The C‐terminus of Bfa1p in budding yeast is essential to induce mitotic arrest in response to diverse checkpoint‐activating signals J Kim, J Jeong, K Song Genes to Cells 9 (5), 399-418, 2004 | 12 | 2004 |
IBD2 encodes a novel component of the Bub2p-dependent spindle checkpoint in the budding yeast Saccharomyces cerevisiae. HS Hwang, YI Jung, J Jeong, K Song Spring scientific meeting and general assembly of the Biochemical Society of …, 2002 | 10 | 2002 |
The RORɣ/SREBP2 pathway is a master regulator of cholesterol metabolism and serves as potential therapeutic target in t(4;11) leukemia E Erkner, T Hentrich, R Schairer, R Fitzel, KA Secker-Grob, J Jeong, ... Oncogene 43 (4), 281-293, 2024 | 1 | 2024 |
Genome editing–induced t (4; 11) chromosomal translocations model B cell precursor acute lymphoblastic leukemias with KMT2A-AFF1 fusion F Pan, J Sarno, J Jeong, X Yang, A Jager, TA Gruber, KL Davis, ... The Journal of Clinical Investigation 134 (1), 2024 | | 2024 |
Inhibition of SREBP2 leads to antileukemic Effects in t (4; 11) Leukemias by Affecting the deregulated Cholesterol Metabolism E Erkner, T Hentrich, R Fitzel, H Keppeler, F Korkmaz, J Jeong, ... ONCOLOGY RESEARCH AND TREATMENT 45 (SUPPL 2), 31-31, 2022 | | 2022 |
Targeting dysregulated cholesterol metabolism in MLL-rearranged leukemia t (4; 11) diminishes l eukemia activity E Erkner, KA Secker, H Keppeler, F Korkmaz, R Fitzel, J Jeong, T Hentrich, ... ONCOLOGY RESEARCH AND TREATMENT 44, 113-114, 2021 | | 2021 |
MAT2A promotes MLLr leukemogenesis and serves as therapeutic target KA Secker, B Bloechl, H Keppeler, S Duerr-Stoerzer, H Schmid, ... ONCOLOGY RESEARCH AND TREATMENT 43 (SUPPL 4), 247-247, 2020 | | 2020 |
Only hematopoietic stem cells derived from cord blood are amenable to malignant progression by MLL-AF4 translocations L Bruns, KA Secker, H Keppeler, J Jeong, T Hentrich, J Schulze-Hentrich, ... ONCOLOGY RESEARCH AND TREATMENT 43 (SUPPL 4), 253-253, 2020 | | 2020 |
MAT2A as key regulator and therapeutic target in MLL leukemogenesis B Bloechl, KA Secker, H Keppeler, S Duerr-Stoerzer, H Schmid, J Jeong, ... ONCOLOGY RESEARCH AND TREATMENT 42, 26-26, 2019 | | 2019 |
Genome editing of primary human HSPCs generates MLL leukemias charcterized by CD9 surface expression C Schneidawind, J Jeong, D Schneidawind, EH Breese, M Porteus, ... ONCOLOGY RESEARCH AND TREATMENT 40, 51-52, 2017 | | 2017 |
CD9 surface expression marks human MLL rearranged cells generated by genome editing C Schneidawind, J Jeong, D Schneidawind, EH Breese, M Porteus, ... ONCOLOGY RESEARCH AND TREATMENT 40, 144-144, 2017 | | 2017 |