| Intraneuronal amyloid‐β1‐42 production triggered by sustained increase of cytosolic calcium concentration induces neuronal death N Pierrot, P Ghisdal, AS Caumont, JN Octave Journal of neurochemistry 88 (5), 1140-1150, 2004 | 187 | 2004 |
| Lack of tau proteins rescues neuronal cell death and decreases amyloidogenic processing of APP in APP/PS1 mice K Leroy, K Ando, V Laporte, R Dedecker, V Suain, M Authelet, C Héraud, ... The American journal of pathology 181 (6), 1928-1940, 2012 | 169 | 2012 |
| Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice IC Stancu, B Vasconcelos, L Ris, P Wang, A Villers, E Peeraer, A Buist, ... Acta neuropathologica 129, 875-894, 2015 | 159 | 2015 |
| Molecular identification of aspartate N-acetyltransferase and its mutation in hypoacetylaspartia E Wiame, D Tyteca, N Pierrot, F Collard, M Amyere, G Noel, J Desmedt, ... Biochemical Journal 425 (1), 127-139, 2010 | 155 | 2010 |
| Calcium-mediated transient phosphorylation of tau and amyloid precursor protein followed by intraneuronal amyloid-β accumulation N Pierrot, SF Santos, C Feyt, M Morel, JP Brion, JN Octave Journal of Biological Chemistry 281 (52), 39907-39914, 2006 | 141 | 2006 |
| Amyloid precursor protein controls cholesterol turnover needed for neuronal activity N Pierrot, D Tyteca, L D'auria, I Dewachter, P Gailly, A Hendrickx, ... EMBO molecular medicine 5 (4), 608-625, 2013 | 109 | 2013 |
| Activation of phagocytic activity in astrocytes by reduced expression of the inflammasome component ASC and its implication in a mouse model of Alzheimer disease J Couturier, IC Stancu, O Schakman, N Pierrot, F Huaux, ... Journal of neuroinflammation 13, 1-13, 2016 | 98 | 2016 |
| Increasing membrane cholesterol of neurons in culture recapitulates Alzheimer’s disease early phenotypes C Marquer, J Laine, L Dauphinot, L Hanbouch, C Lemercier-Neuillet, ... Molecular neurodegeneration 9, 1-13, 2014 | 92 | 2014 |
| Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo P Wang, G Joberty, A Buist, A Vanoosthuyse, IC Stancu, B Vasconcelos, ... Acta neuropathologica 133, 731-749, 2017 | 90 | 2017 |
| Processing of amyloid precursor protein and amyloid peptide neurotoxicity P Nathalie, O Jean-Noel Current Alzheimer Research 5 (2), 92-99, 2008 | 86 | 2008 |
| Epigenetic regulations of immediate early genes expression involved in memory formation by the amyloid precursor protein of Alzheimer disease A Hendrickx, N Pierrot, B Tasiaux, O Schakman, P Kienlen-Campard, ... PloS one 9 (6), e99467, 2014 | 78 | 2014 |
| Epigenetic regulations of immediate early genes expression involved in memory formation by the amyloid precursor protein of Alzheimer disease A Hendrickx, N Pierrot, B Tasiaux, O Schakman, P Kienlen-Campard, ... PloS one 9 (6), e99467, 2014 | 78 | 2014 |
| Expression of human amyloid precursor protein in rat cortical neurons inhibits calcium oscillations SF Santos, N Pierrot, N Morel, P Gailly, C Sindic, JN Octave Journal of Neuroscience 29 (15), 4708-4718, 2009 | 74 | 2009 |
| From synaptic spines to nuclear signaling: nuclear and synaptic actions of the amyloid precursor protein JN Octave, N Pierrot, S Ferao Santos, NN Nalivaeva, AJ Turner Journal of neurochemistry 126 (2), 183-190, 2013 | 70 | 2013 |
| Network excitability dysfunction in Alzheimer's disease: insights from in vitro and in vivo models S Ferrao Santos, N Pierrot, JN Octave Reviews in the neurosciences 21 (3), 153-172, 2010 | 48 | 2010 |
| Tauopathy contributes to synaptic and cognitive deficits in a murine model for Alzheimer's disease IC Stancu, L Ris, B Vasconcelos, C Marinangeli, L Goeminne, V Laporte, ... The FASEB Journal 28 (6), 2620-2631, 2014 | 47 | 2014 |
| Phosphorylation of APP695 at Thr668 decreases γ-cleavage and extracellular Aβ C Feyt, N Pierrot, B Tasiaux, J Van Hees, P Kienlen-Campard, PJ Courtoy, ... Biochemical and biophysical research communications 357 (4), 1004-1010, 2007 | 42 | 2007 |
| Alzheimer’s disease, a lipid story: involvement of peroxisome proliferator-activated receptor α F Sáez-Orellana, JN Octave, N Pierrot Cells 9 (5), 1215, 2020 | 38 | 2020 |
| Cortical cells reveal APP as a new player in the regulation of GABAergic neurotransmission A Doshina, F Gourgue, M Onizuka, R Opsomer, P Wang, K Ando, ... Scientific reports 7 (1), 370, 2017 | 37 | 2017 |
| Targretin improves cognitive and biological markers in a patient with Alzheimer’s disease N Pierrot, R Lhommel, L Quenon, B Hanseeuw, L Dricot, C Sindic, ... Journal of Alzheimer's Disease 49 (2), 271-276, 2016 | 33 | 2016 |
