| A metabolite-derived protein modification integrates glycolysis with KEAP1–NRF2 signalling MJ Bollong, G Lee, JS Coukos, H Yun, C Zambaldo, JW Chang, EN Chin, ... Nature 562 (7728), 600-604, 2018 | 230 | 2018 |
| Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria X Luo, G Fu, RE Wang, X Zhu, C Zambaldo, R Liu, T Liu, X Lyu, J Du, ... Nature chemical biology 13 (8), 845-849, 2017 | 123 | 2017 |
| PNA-encoded chemical libraries C Zambaldo, S Barluenga, N Winssinger Current opinion in chemical biology 26, 8-15, 2015 | 91 | 2015 |
| DNA display of fragment pairs as a tool for the discovery of novel biologically active small molecules JP Daguer, C Zambaldo, M Ciobanu, P Morieux, S Barluenga, ... Chemical science 6 (1), 739-744, 2015 | 82 | 2015 |
| Expanding the Scope of PNA‐Encoded Synthesis (PES): Mtt‐Protected PNA Fully Orthogonal to Fmoc Chemistry and a Broad Array of Robust Diversity‐Generating Reactions D Chouikhi, M Ciobanu, C Zambaldo, V Duplan, S Barluenga, ... Chemistry–A European Journal 18 (40), 12698-12704, 2012 | 75 | 2012 |
| 2-Sulfonylpyridines as tunable, cysteine-reactive electrophiles C Zambaldo, EV Vinogradova, X Qi, J Iaconelli, RM Suciu, M Koh, ... Journal of the American Chemical Society 142 (19), 8972-8979, 2020 | 73 | 2020 |
| Small molecule-mediated inhibition of myofibroblast transdifferentiation for the treatment of fibrosis MJ Bollong, B Yang, N Vergani, BA Beyer, EN Chin, C Zambaldo, D Wang, ... Proceedings of the National Academy of Sciences 114 (18), 4679-4684, 2017 | 69 | 2017 |
| Recombinant thiopeptides containing noncanonical amino acids X Luo, C Zambaldo, T Liu, Y Zhang, W Xuan, C Wang, SA Reed, PY Yang, ... Proceedings of the National Academy of Sciences 113 (13), 3615-3620, 2016 | 68 | 2016 |
| Screening for covalent inhibitors using DNA-display of small molecule libraries functionalized with cysteine reactive moieties C Zambaldo, JP Daguer, J Saarbach, S Barluenga, N Winssinger MedChemComm 7 (7), 1340-1351, 2016 | 64 | 2016 |
| Identification of covalent bromodomain binders through DNA display of small molecules JP Daguer, C Zambaldo, D Abegg, S Barluenga, C Tallant, S Müller, ... Angewandte Chemie International Edition 54 (20), 6057-6061, 2015 | 60 | 2015 |
| Targeted delivery of an anti-inflammatory PDE4 inhibitor to immune cells via an antibody–drug conjugate S Yu, AD Pearson, RKV Lim, DT Rodgers, S Li, HB Parker, M Weglarz, ... Molecular Therapy 24 (12), 2078-2089, 2016 | 50 | 2016 |
| Recombinant macrocyclic lanthipeptides incorporating non-canonical amino acids C Zambaldo, X Luo, AP Mehta, PG Schultz Journal of the american chemical society 139 (34), 11646-11649, 2017 | 44 | 2017 |
| Novel PTP1B inhibitors identified by DNA display of fragment pairs S Barluenga, C Zambaldo, HA Ioannidou, M Ciobanu, P Morieux, ... Bioorganic & medicinal chemistry letters 26 (3), 1080-1085, 2016 | 38 | 2016 |
| Asymmetric synthesis of pochonin E and F, revision of their proposed structure, and their conversion to potent Hsp90 inhibitors G Karthikeyan, C Zambaldo, S Barluenga, V Zoete, M Karplus, ... Chemistry–A European Journal 18 (29), 8978-8986, 2012 | 30 | 2012 |
| YAP-dependent proliferation by a small molecule targeting annexin A2 SZ Shalhout, PY Yang, EM Grzelak, K Nutsch, S Shao, C Zambaldo, ... Nature Chemical Biology 17 (7), 767-775, 2021 | 29 | 2021 |
| Selective affinity-based probe for oncogenic kinases suitable for live cell imaging C Zambaldo, KK Sadhu, G Karthikeyan, S Barluenga, JP Daguer, ... Chemical Science 4 (5), 2088-2092, 2013 | 27 | 2013 |
| High-throughput solid-phase building block synthesis for DNA-encoded libraries C Zambaldo, SN Geigle, AL Satz Organic letters 21 (23), 9353-9357, 2019 | 15 | 2019 |
| Facile access to modified and functionalized PNAs through Ugi-based solid phase oligomerization J Saarbach, D Masi, C Zambaldo, N Winssinger Bioorganic & medicinal chemistry 25 (19), 5171-5177, 2017 | 13 | 2017 |
| An orthogonal seryl-tRNA synthetase/tRNA pair for noncanonical amino acid mutagenesis in Escherichia coli C Zambaldo, M Koh, F Nasertorabi, GW Han, A Chatterjee, RC Stevens, ... Bioorganic & medicinal chemistry 28 (20), 115662, 2020 | 11 | 2020 |
| Identifizierung von niedermolekularen kovalenten Bromodomäne‐Bindern aus einer DNA‐kodierten Bibliothek JP Daguer, C Zambaldo, D Abegg, S Barluenga, C Tallant, S Müller, ... Angewandte Chemie 127 (20), 6155-6159, 2015 | 7 | 2015 |
Nicolas WinssingerProfessor of chemistry, University of GenevaVerified email at unige.ch
