Tomas Obsil
Tomas Obsil
Charles University in Prague, Faculty of Science
E-mailová adresa ověřena na: natur.cuni.cz - Domovská stránka
NázevCitaceRok
Activation and regulation of purinergic P2X receptor channels
C Coddou, Z Yan, T Obsil, JP Huidobro-Toro, SS Stojilkovic
Pharmacological reviews 63 (3), 641-683, 2011
3922011
Crystal structure of the 14-3-3ζ: serotonin N-acetyltransferase complex: a role for scaffolding in enzyme regulation
T Obsil, R Ghirlando, DC Klein, S Ganguly, F Dyda
Cell 105 (2), 257-267, 2001
3872001
Structural basis of 14-3-3 protein functions
T Obsil, V Obsilova
Seminars in cell & developmental biology 22 (7), 663-672, 2011
2112011
Structure/function relationships underlying regulation of FOXO transcription factors
T Obsil, V Obsilova
Oncogene 27 (16), 2263, 2008
2072008
Role of a pineal cAMP-operated arylalkylamine N-acetyltransferase/14-3-3-binding switch in melatonin synthesis
S Ganguly, JA Gastel, JL Weller, C Schwartz, H Jaffe, MAA Namboodiri, ...
Proceedings of the National Academy of Sciences 98 (14), 8083-8088, 2001
1622001
14-3-3 proteins: a family of versatile molecular regulators
V Obšlova, J Šilhan, E BouŔa, J Teisinger, T Obšil
Physiol Res, S11-S21, 2008
1602008
14-3-3 Protein interacts with nuclear localization sequence of forkhead transcription factor FoxO4
V Obsilova, J Vecer, P Herman, A Pabianova, M Sulc, J Teisinger, ...
Biochemistry 44 (34), 11608-11617, 2005
1232005
Two 14-3-3 binding motifs are required for stable association of Forkhead transcription factor FOXO4 with 14-3-3 proteins and inhibition of DNA binding
T Obsil, R Ghirlando, DE Anderson, AB Hickman, F Dyda
Biochemistry 42 (51), 15264-15272, 2003
1162003
Hippo/Mst1 stimulates transcription of the proapoptotic mediator NOXA in a FoxO1-dependent manner
K Valis, L Prochazka, E Boura, J Chladova, T Obsil, J Rohlena, J Truksa, ...
Cancer research 71 (3), 946-954, 2011
832011
14-3-3ζ C-terminal stretch changes its conformation upon ligand binding and phosphorylation at Thr232
V Obsilova, P Herman, J Vecer, M Sulc, J Teisinger, T Obsil
Journal of Biological Chemistry 279 (6), 4531-4540, 2004
812004
Both the N-terminal loop and wing W2 of the forkhead domain of transcription factor Foxo4 are important for DNA binding
E Boura, J Silhan, P Herman, J Vecer, M Sulc, J Teisinger, V Obsilova, ...
Journal of Biological Chemistry 282 (11), 8265-8275, 2007
732007
Structural basis for DNA recognition by FOXO proteins
T Obsil, V Obsilova
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1813 (11), 1946-1953, 2011
692011
Mechanisms of the 14-3-3 protein function: regulation of protein function through conformational modulation.
V Obsilova, M Kopecka, D Kosek, M Kacirova, S Kylarova, L Rezabkova, ...
Physiological research 63, 2014
682014
Molecular determinants of the agonist binding domain of a P2X receptor channel
Z Yan, Z Liang, M Tomić, T Obsil, SS Stojilkovic
Molecular pharmacology 67 (4), 1078-1088, 2005
682005
Identification of P2X4 receptor transmembrane residues contributing to channel gating and interaction with ivermectin
I Jelínkova, V Vávra, M Jindrichova, T Obsil, HW Zemkova, H Zemkova, ...
Pflügers Archiv-European Journal of Physiology 456 (5), 939-950, 2008
642008
Identification of P2X4 receptor transmembrane residues contributing to channel gating and interaction with ivermectin
I Jelínkova, V Vávra, M Jindrichova, T Obsil, HW Zemkova, H Zemkova, ...
Pflügers Archiv-European Journal of Physiology 456 (5), 939-950, 2008
642008
Participation of the Lys313-Ile333 sequence of the purinergic P2X4 receptor in agonist binding and transduction of signals to the channel gate
Z Yan, Z Liang, T Obsil, SS Stojilkovic
Journal of Biological Chemistry 281 (43), 32649-32659, 2006
642006
14-3-3 Proteins and photoneuroendocrine transduction: role in controlling the daily rhythm in melatonin
DC Klein, S Ganguly, S Coon, JL Weller, T Obsil, A Hickman, F Dyda
Biochemical Society Transactions 30 (4), 365-373, 2002
632002
The 14-3-3 protein affects the conformation of the regulatory domain of human tyrosine hydroxylase
V Obsilova, E Nedbalkova, J Silhan, E Boura, P Herman, J Vecer, M Sulc, ...
Biochemistry 47 (6), 1768-1777, 2008
622008
14-3-3 protein C-terminal stretch occupies ligand binding groove and is displaced by phosphopeptide binding
J Silhan, V Obsilova, J Vecer, P Herman, M Sulc, J Teisinger, T Obsil
Journal of Biological Chemistry 279 (47), 49113-49119, 2004
572004
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Články 1–20