Sledovat
Gautham Vivek Sridharan
Gautham Vivek Sridharan
Associate Director, Alnylam Pharmaceuticals
E-mailová adresa ověřena na: alnylam.com
Název
Citace
Citace
Rok
Gut microbiota-derived tryptophan metabolites modulate inflammatory response in hepatocytes and macrophages
S Krishnan, Y Ding, N Saedi, M Choi, GV Sridharan, DH Sherr, ...
Cell reports 23 (4), 1099-1111, 2018
5852018
Microbiome-derived tryptophan metabolites and their aryl hydrocarbon receptor-dependent agonist and antagonist activities
UH Jin, SO Lee, G Sridharan, K Lee, LA Davidson, A Jayaraman, ...
Molecular pharmacology 85 (5), 777-788, 2014
3442014
Quantitative metabolic imaging using endogenous fluorescence to detect stem cell differentiation
KP Quinn, GV Sridharan, RS Hayden, DL Kaplan, K Lee, I Georgakoudi
Scientific reports 3 (1), 3432, 2013
3082013
Prediction and quantification of bioactive microbiota metabolites in the mouse gut
GV Sridharan, K Choi, C Klemashevich, C Wu, D Prabakaran, LB Pan, ...
Nature communications 5 (1), 5492, 2014
2692014
Endogenous two-photon fluorescence imaging elucidates metabolic changes related to enhanced glycolysis and glutamine consumption in precancerous epithelial tissues
A Varone, J Xylas, KP Quinn, D Pouli, G Sridharan, ...
Cancer research 74 (11), 3067-3075, 2014
1752014
Metabolic profiling during ex vivo machine perfusion of the human liver
BG Bruinsma, GV Sridharan, PD Weeder, JH Avruch, N Saeidi, S Özer, ...
Scientific reports 6 (1), 22415, 2016
1282016
Lysyl oxidase-mediated collagen crosslinks may be assessed as markers of functional properties of tendon tissue formation
JE Marturano, JF Xylas, GV Sridharan, I Georgakoudi, CK Kuo
Acta biomaterialia 10 (3), 1370-1379, 2014
1192014
Neurofilament light chain as a biomarker of hereditary transthyretin-mediated amyloidosis
S Ticau, GV Sridharan, S Tsour, WL Cantley, A Chan, JA Gilbert, D Erbe, ...
Neurology 96 (3), e412-e422, 2021
802021
Hepatic gap junctions amplify alcohol liver injury by propagating cGAS-mediated IRF3 activation
J Luther, S Khan, MK Gala, D Kedrin, G Sridharan, RP Goodman, ...
Proceedings of the National Academy of Sciences 117 (21), 11667-11673, 2020
792020
Functional human liver preservation and recovery by means of subnormothermic machine perfusion
BG Bruinsma, JH Avruch, PD Weeder, GV Sridharan, BE Uygun, ...
Journal of visualized experiments: JoVE, 52777, 2015
472015
Peritransplant energy changes and their correlation to outcome after human liver transplantation
BG Bruinsma, JH Avruch, GV Sridharan, PD Weeder, ML Jacobs, ...
Transplantation 101 (7), 1637-1644, 2017
352017
Identification of biochemical network modules based on shortest retroactive distances
GV Sridharan, S Hassoun, K Lee
PLoS computational biology 7 (11), e1002262, 2011
202011
Analysis of transcription factor network underlying 3T3-L1 adipocyte differentiation
KO Choi, B Ghaddar, C Moya, H Shi, GV Sridharan, K Lee, A Jayaraman
PLoS One 9 (7), e100177, 2014
172014
A novel low-volume two-chamber microfabricated platform for evaluating drug metabolism and toxicity
SS Bale, GV Sridharan, I Golberg, L Prodanov, WJ McCarty, OB Usta, ...
Technology 3 (04), 155-162, 2015
152015
Discovery of substrate cycles in large scale metabolic networks using hierarchical modularity
GV Sridharan, E Ullah, S Hassoun, K Lee
BMC Systems Biology 9, 1-11, 2015
102015
In silico modeling of the impact of antithrombin lowering on thrombin generation in rare bleeding disorders
G Sridharan, J Liu, K Qian, V Goel, S Huang, A Akinc
Blood 130, 3659, 2017
82017
Metabolomic modularity analysis (MMA) to quantify human liver perfusion dynamics
GV Sridharan, BG Bruinsma, SS Bale, A Swaminathan, N Saeidi, ...
Metabolites 7 (4), 58, 2017
82017
Metabolic flux-based modularity using shortest retroactive distances
GV Sridharan, M Yi, S Hassoun, K Lee
BMC systems biology 6, 1-14, 2012
72012
Multi-omic network-based interrogation of rat liver metabolism following gastric bypass surgery featuring SWATH proteomics
GV Sridharan, M D’Alessandro, SS Bale, V Bhagat, H Gagnon, JM Asara, ...
Technology 5 (03), 139-184, 2017
52017
A novel model for ex situ reperfusion of the human liver following subnormothermic machine perfusion
JH Avruch, BG Bruinsma, PD Weeder, GV Sridharan, RJ Porte, H Yeh, ...
Technology 5 (04), 196-200, 2017
42017
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Články 1–20