| Integration of external signaling pathways with the core transcriptional network in embryonic stem cells X Chen, H Xu, P Yuan, F Fang, M Huss, VB Vega, E Wong, YL Orlov, ... Cell 133 (6), 1106-1117, 2008 | 2987 | 2008 |
| Partitioning heritability by functional annotation using genome-wide association summary statistics HK Finucane, B Bulik-Sullivan, A Gusev, G Trynka, Y Reshef, PR Loh, ... Nature genetics 47 (11), 1228-1235, 2015 | 2405 | 2015 |
| MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens W Li, H Xu, T Xiao, L Cong, MI Love, F Zhang, RA Irizarry, JS Liu, ... Genome biology 15, 1-12, 2014 | 2151 | 2014 |
| An oestrogen-receptor-α-bound human chromatin interactome MJ Fullwood, MH Liu, YF Pan, J Liu, H Xu, YB Mohamed, YL Orlov, ... Nature 462 (7269), 58-64, 2009 | 2020 | 2009 |
| Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells RM Meyers, JG Bryan, JM McFarland, BA Weir, AE Sizemore, H Xu, ... Nature genetics 49 (12), 1779-1784, 2017 | 1705 | 2017 |
| EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent K Xu, ZJ Wu, AC Groner, HH He, C Cai, RT Lis, X Wu, EC Stack, M Loda, ... Science 338 (6113), 1465-1469, 2012 | 978 | 2012 |
| CTCF-mediated functional chromatin interactome in pluripotent cells L Handoko, H Xu, G Li, CY Ngan, E Chew, M Schnapp, CWH Lee, C Ye, ... Nature genetics 43 (7), 630-638, 2011 | 773 | 2011 |
| Sequence determinants of improved CRISPR sgRNA design H Xu, T Xiao, CH Chen, W Li, CA Meyer, Q Wu, D Wu, L Cong, F Zhang, ... Genome research 25 (8), 1147-1157, 2015 | 704 | 2015 |
| Genomic copy number dictates a gene-independent cell response to CRISPR/Cas9 targeting AJ Aguirre, RM Meyers, BA Weir, F Vazquez, CZ Zhang, U Ben-David, ... Cancer discovery 6 (8), 914-929, 2016 | 681 | 2016 |
| Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases A Gusev, SH Lee, G Trynka, H Finucane, BJ Vilhjálmsson, H Xu, C Zang, ... The American Journal of Human Genetics 95 (5), 535-552, 2014 | 674 | 2014 |
| Chromatin marks identify critical cell types for fine mapping complex trait variants G Trynka, C Sandor, B Han, H Xu, BE Stranger, XS Liu, S Raychaudhuri Nature genetics 45 (2), 124-130, 2013 | 665 | 2013 |
| Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells XD Zhao, X Han, JL Chew, J Liu, KP Chiu, A Choo, YL Orlov, WK Sung, ... Cell stem cell 1 (3), 286-298, 2007 | 664 | 2007 |
| Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR–Cas9 library S Zhu, W Li, J Liu, CH Chen, Q Liao, P Xu, H Xu, T Xiao, Z Cao, J Peng, ... Nature biotechnology 34 (12), 1279-1286, 2016 | 483 | 2016 |
| Quality control, modeling, and visualization of CRISPR screens with MAGeCK-VISPR W Li, J Köster, H Xu, CH Chen, T Xiao, JS Liu, M Brown, XS Liu Genome biology 16, 1-13, 2015 | 440 | 2015 |
| ChIA-PET tool for comprehensive chromatin interaction analysis with paired-end tag sequencing G Li, MJ Fullwood, H Xu, FH Mulawadi, S Velkov, V Vega, PN Ariyaratne, ... Genome biology 11, 1-13, 2010 | 380 | 2010 |
| Refined DNase-seq protocol and data analysis reveals intrinsic bias in transcription factor footprint identification HH He, CA Meyer, SS Hu, MW Chen, C Zang, Y Liu, PK Rao, T Fei, H Xu, ... Nature methods 11 (1), 73-78, 2014 | 274 | 2014 |
| Genome-wide mapping of RELA (p65) binding identifies E2F1 as a transcriptional activator recruited by NF-κB upon TLR4 activation CA Lim, F Yao, JJY Wong, J George, H Xu, KP Chiu, WK Sung, L Lipovich, ... Molecular cell 27 (4), 622-635, 2007 | 237 | 2007 |
| An HMM approach to genome-wide identification of differential histone modification sites from ChIP-seq data H Xu, CL Wei, F Lin, WK Sung Bioinformatics 24 (20), 2344-2349, 2008 | 201 | 2008 |
| A signal–noise model for significance analysis of ChIP-seq with negative control H Xu, L Handoko, X Wei, C Ye, J Sheng, CL Wei, F Lin, WK Sung Bioinformatics 26 (9), 1199-1204, 2010 | 190 | 2010 |
| Disentangling the effects of colocalizing genomic annotations to functionally prioritize non-coding variants within complex-trait loci G Trynka, HJ Westra, K Slowikowski, X Hu, H Xu, BE Stranger, RJ Klein, ... The American Journal of Human Genetics 97 (1), 139-152, 2015 | 150 | 2015 |
