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Han Xu
Han Xu
Dana Farber Cancer Institute
Žádná ověřená e-mailová adresa
Název
Citace
Citace
Rok
Integration of external signaling pathways with the core transcriptional network in embryonic stem cells
X Chen, H Xu, P Yuan, F Fang, M Huss, VB Vega, E Wong, YL Orlov, ...
Cell 133 (6), 1106-1117, 2008
29872008
Partitioning heritability by functional annotation using genome-wide association summary statistics
HK Finucane, B Bulik-Sullivan, A Gusev, G Trynka, Y Reshef, PR Loh, ...
Nature genetics 47 (11), 1228-1235, 2015
24052015
MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens
W Li, H Xu, T Xiao, L Cong, MI Love, F Zhang, RA Irizarry, JS Liu, ...
Genome biology 15, 1-12, 2014
21512014
An oestrogen-receptor-α-bound human chromatin interactome
MJ Fullwood, MH Liu, YF Pan, J Liu, H Xu, YB Mohamed, YL Orlov, ...
Nature 462 (7269), 58-64, 2009
20202009
Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells
RM Meyers, JG Bryan, JM McFarland, BA Weir, AE Sizemore, H Xu, ...
Nature genetics 49 (12), 1779-1784, 2017
17052017
EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent
K Xu, ZJ Wu, AC Groner, HH He, C Cai, RT Lis, X Wu, EC Stack, M Loda, ...
Science 338 (6113), 1465-1469, 2012
9782012
CTCF-mediated functional chromatin interactome in pluripotent cells
L Handoko, H Xu, G Li, CY Ngan, E Chew, M Schnapp, CWH Lee, C Ye, ...
Nature genetics 43 (7), 630-638, 2011
7732011
Sequence determinants of improved CRISPR sgRNA design
H Xu, T Xiao, CH Chen, W Li, CA Meyer, Q Wu, D Wu, L Cong, F Zhang, ...
Genome research 25 (8), 1147-1157, 2015
7042015
Genomic copy number dictates a gene-independent cell response to CRISPR/Cas9 targeting
AJ Aguirre, RM Meyers, BA Weir, F Vazquez, CZ Zhang, U Ben-David, ...
Cancer discovery 6 (8), 914-929, 2016
6812016
Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases
A Gusev, SH Lee, G Trynka, H Finucane, BJ Vilhjálmsson, H Xu, C Zang, ...
The American Journal of Human Genetics 95 (5), 535-552, 2014
6742014
Chromatin marks identify critical cell types for fine mapping complex trait variants
G Trynka, C Sandor, B Han, H Xu, BE Stranger, XS Liu, S Raychaudhuri
Nature genetics 45 (2), 124-130, 2013
6652013
Whole-genome mapping of histone H3 Lys4 and 27 trimethylations reveals distinct genomic compartments in human embryonic stem cells
XD Zhao, X Han, JL Chew, J Liu, KP Chiu, A Choo, YL Orlov, WK Sung, ...
Cell stem cell 1 (3), 286-298, 2007
6642007
Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR–Cas9 library
S Zhu, W Li, J Liu, CH Chen, Q Liao, P Xu, H Xu, T Xiao, Z Cao, J Peng, ...
Nature biotechnology 34 (12), 1279-1286, 2016
4832016
Quality control, modeling, and visualization of CRISPR screens with MAGeCK-VISPR
W Li, J Köster, H Xu, CH Chen, T Xiao, JS Liu, M Brown, XS Liu
Genome biology 16, 1-13, 2015
4402015
ChIA-PET tool for comprehensive chromatin interaction analysis with paired-end tag sequencing
G Li, MJ Fullwood, H Xu, FH Mulawadi, S Velkov, V Vega, PN Ariyaratne, ...
Genome biology 11, 1-13, 2010
3802010
Refined DNase-seq protocol and data analysis reveals intrinsic bias in transcription factor footprint identification
HH He, CA Meyer, SS Hu, MW Chen, C Zang, Y Liu, PK Rao, T Fei, H Xu, ...
Nature methods 11 (1), 73-78, 2014
2742014
Genome-wide mapping of RELA (p65) binding identifies E2F1 as a transcriptional activator recruited by NF-κB upon TLR4 activation
CA Lim, F Yao, JJY Wong, J George, H Xu, KP Chiu, WK Sung, L Lipovich, ...
Molecular cell 27 (4), 622-635, 2007
2372007
An HMM approach to genome-wide identification of differential histone modification sites from ChIP-seq data
H Xu, CL Wei, F Lin, WK Sung
Bioinformatics 24 (20), 2344-2349, 2008
2012008
A signal–noise model for significance analysis of ChIP-seq with negative control
H Xu, L Handoko, X Wei, C Ye, J Sheng, CL Wei, F Lin, WK Sung
Bioinformatics 26 (9), 1199-1204, 2010
1902010
Disentangling the effects of colocalizing genomic annotations to functionally prioritize non-coding variants within complex-trait loci
G Trynka, HJ Westra, K Slowikowski, X Hu, H Xu, BE Stranger, RJ Klein, ...
The American Journal of Human Genetics 97 (1), 139-152, 2015
1502015
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Články 1–20