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Multiplex genome-edited T-cell manufacturing platform for “off-the-shelf” adoptive T-cell immunotherapies L Poirot, B Philip, C Schiffer-Mannioui, D Le Clerre, I Chion-Sotinel, ... Cancer research 75 (18), 3853-3864, 2015 | 624 | 2015 |
CAR T cell trogocytosis and cooperative killing regulate tumour antigen escape M Hamieh, A Dobrin, A Cabriolu, SJC van der Stegen, T Giavridis, ... Nature 568 (7750), 112-116, 2019 | 487 | 2019 |
Calibration of CAR activation potential directs alternative T cell fates and therapeutic potency J Feucht, J Sun, J Eyquem, YJ Ho, Z Zhao, J Leibold, A Dobrin, A Cabriolu, ... Nature medicine 25 (1), 82-88, 2019 | 422 | 2019 |
Integrating proteomics and transcriptomics for systematic combinatorial chimeric antigen receptor therapy of AML F Perna, SH Berman, RK Soni, J Mansilla-Soto, J Eyquem, M Hamieh, ... Cancer cell 32 (4), 506-519. e5, 2017 | 276 | 2017 |
Low-dose radiation conditioning enables CAR T cells to mitigate antigen escape C DeSelm, ML Palomba, J Yahalom, M Hamieh, J Eyquem, ... Molecular Therapy 26 (11), 2542-2552, 2018 | 190 | 2018 |
A platform for rapid prototyping of synthetic gene networks in mammalian cells X Duportet, L Wroblewska, P Guye, Y Li, J Eyquem, J Rieders, T Rimchala, ... Nucleic acids research 42 (21), 13440-13451, 2014 | 153 | 2014 |
HLA-independent T cell receptors for targeting tumors with low antigen density J Mansilla-Soto, J Eyquem, S Haubner, M Hamieh, J Feucht, N Paillon, ... Nature medicine 28 (2), 345-352, 2022 | 89 | 2022 |
High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails BR Shy, VS Vykunta, A Ha, A Talbot, TL Roth, DN Nguyen, WG Pfeifer, ... Nature biotechnology 41 (4), 521-531, 2023 | 85 | 2023 |
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Antibody with infinite affinity for in vivo tracking of genetically engineered lymphocytes S Krebs, A Ahad, LM Carter, J Eyquem, C Brand, M Bell, V Ponomarev, ... Journal of Nuclear Medicine 59 (12), 1894-1900, 2018 | 42 | 2018 |
The surfaceome of multiple myeloma cells suggests potential immunotherapeutic strategies and protein markers of drug resistance ID Ferguson, B Patiño-Escobar, ST Tuomivaara, YHT Lin, MA Nix, ... Nature communications 13 (1), 4121, 2022 | 39 | 2022 |
Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells CA Tsuchida, N Brandes, R Bueno, M Trinidad, T Mazumder, B Yu, ... Cell 186 (21), 4567-4582. e20, 2023 | 35 | 2023 |
Generation of T-cell-receptor-negative CD8αβ-positive CAR T cells from T-cell-derived induced pluripotent stem cells SJC van der Stegen, PL Lindenbergh, RM Petrovic, H Xie, MP Diop, ... Nature biomedical engineering 6 (11), 1284-1297, 2022 | 34 | 2022 |
Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes DV Foss, JJ Muldoon, DN Nguyen, D Carr, SU Sahu, JM Hunsinger, ... Nature Biomedical Engineering 7 (5), 647-660, 2023 | 33 | 2023 |
Pooled screening of CAR T cells identifies diverse immune signaling domains for next-generation immunotherapies DB Goodman, CS Azimi, K Kearns, A Talbot, K Garakani, J Garcia, ... Science translational medicine 14 (670), eabm1463, 2022 | 30 | 2022 |
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