| The DNA demethylating agent 5-aza-2'-deoxycytidine induces expression of NY-ESO-1 and other cancer/testis antigens in myeloid leukemia cells. M Almstedt, N Blagitko-Dorfs, J Duque-Afonso, J Karbach, D Pfeifer, ... Leukemia research 34 (7), 899, 2010 | 208 | 2010 |
| ASH1L links histone H3 lysine 36 dimethylation to MLL leukemia L Zhu, Q Li, SHK Wong, M Huang, BJ Klein, J Shen, L Ikenouye, M Onishi, ... Cancer discovery 6 (7), 770-783, 2016 | 134 | 2016 |
| Histone deacetylase inhibitors induce a very broad, pleiotropic anticancer drug resistance phenotype in acute myeloid leukemia cells by modulation of multiple ABC transporter genes S Hauswald, J Duque-Afonso, MM Wagner, FM Schertl, M Lübbert, ... Clinical Cancer Research 15 (11), 3705-3715, 2009 | 131 | 2009 |
| The H3K4-methyl epigenome regulates leukemia stem cell oncogenic potential SHK Wong, DL Goode, M Iwasaki, MC Wei, HP Kuo, L Zhu, ... Cancer cell 28 (2), 198-209, 2015 | 123 | 2015 |
| Epigenetic roles of MLL oncoproteins are dependent on NF-κB HP Kuo, Z Wang, DF Lee, M Iwasaki, J Duque-Afonso, SHK Wong, CH Lin, ... Cancer cell 24 (4), 423-437, 2013 | 92 | 2013 |
| Complementing mutations in core binding factor leukemias: from mouse models to clinical applications AMS Müller, J Duque, JA Shizuru, M Lübbert Oncogene 27 (44), 5759-5773, 2008 | 85 | 2008 |
| Comparative genomics reveals multistep pathogenesis of E2A-PBX1 acute lymphoblastic leukemia J Duque-Afonso, J Feng, F Scherer, CH Lin, SHK Wong, Z Wang, ... The Journal of Clinical Investigation 125 (9), 3667-3680, 2015 | 73 | 2015 |
| MLL leukemia induction by genome editing of human CD34+ hematopoietic cells C Buechele, EH Breese, D Schneidawind, CH Lin, J Jeong, ... Blood, The Journal of the American Society of Hematology 126 (14), 1683-1694, 2015 | 66 | 2015 |
| The HDAC class I-specific inhibitor entinostat (MS-275) effectively relieves epigenetic silencing of the LAT2 gene mediated by AML1/ETO J Duque-Afonso, A Yalcin, T Berg, M Abdelkarim, O Heidenreich, ... Oncogene 30 (27), 3062-3072, 2011 | 54 | 2011 |
| Structured assessment of frailty in multiple myeloma as a paradigm of individualized treatment algorithms in cancer patients at advanced age M Engelhardt, G Ihorst, J Duque-Afonso, U Wedding, E Spät-Schwalbe, ... Haematologica 105 (5), 1183, 2020 | 51 | 2020 |
| MLL leukemia induction by t (9; 11) chromosomal translocation in human hematopoietic stem cells using genome editing C Schneidawind, J Jeong, D Schneidawind, IS Kim, J Duque-Afonso, ... Blood advances 2 (8), 832-845, 2018 | 36 | 2018 |
| E2A-PBX1 remodels oncogenic signaling networks in B-cell precursor acute lymphoid leukemia J Duque-Afonso, CH Lin, K Han, MC Wei, J Feng, JH Kurzer, ... Cancer research 76 (23), 6937-6949, 2016 | 36 | 2016 |
| Droplet digital PCR for the simultaneous analysis of minimal residual disease and hematopoietic chimerism after allogeneic cell transplantation M Waterhouse, D Pfeifer, J Duque-Afonso, M Follo, J Duyster, M Depner, ... Clinical Chemistry and Laboratory Medicine (CCLM) 57 (5), 641-647, 2019 | 35 | 2019 |
| Two cell lines of t (8; 21) acute myeloid leukemia with activating KIT exon 17 mutation: models for the ‘second hit’hypothesis H Becker, D Pfeifer, JD Afonso, SD Nimer, H Veelken, M Schwabe, ... Leukemia 22 (9), 1792-1794, 2008 | 35 | 2008 |
| Transitioning the molecular tumor board from proof of concept to clinical routine: a German single-center analysis R Hoefflin, A Lazarou, ME Hess, M Reiser, J Wehrle, P Metzger, AV Frey, ... Cancers 13 (5), 1151, 2021 | 34 | 2021 |
| Epigenetic priming of AML blasts for all-trans retinoic acid-induced differentiation by the HDAC class-I selective inhibitor entinostat N Blagitko-Dorfs, Y Jiang, J Duque-Afonso, J Hiller, A Yalcin, G Greve, ... PLoS One 8 (10), e75258, 2013 | 30 | 2013 |
| Cell-free DNA characteristics and chimerism analysis in patients after allogeneic cell transplantation J Duque-Afonso, M Waterhouse, D Pfeifer, M Follo, J Duyster, H Bertz, ... Clinical biochemistry 52, 137-141, 2018 | 29 | 2018 |
| ASH1L links histone H3 lysine 36 dimethylation to MLL leukemia. Cancer Discov. 2016; 6: 770–783. doi: 10.1158/2159-8290 L Zhu, Q Li, SH Wong, M Huang, BJ Klein, J Shen, L Ikenouye, M Onishi, ... CD-16-0058.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 28 | |
| SETDB2 links E2A-PBX1 to cell-cycle dysregulation in acute leukemia through CDKN2C repression CH Lin, SHK Wong, JH Kurzer, C Schneidawind, MC Wei, ... Cell reports 23 (4), 1166-1177, 2018 | 27 | 2018 |
| AML1/ETO and its function as a regulator of gene transcription via epigenetic mechanisms K Rejeski, J Duque-Afonso, M Lübbert Oncogene 40 (38), 5665-5676, 2021 | 26 | 2021 |
Chiou-Hong LinStanford University School of MedicineVerified email at stanford.edu
