Jean Fletcher
T cells in multiple sclerosis and experimental autoimmune encephalomyelitis
KHGM JM Fletcher, SJ Lalor, CM Sweeney, N Tubridy
Clinical and Experimental Immunology 162 (1), 1-11, 2010
Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo
M Vukmanovic-Stejic, Y Zhang, JE Cook, JM Fletcher, A McQuaid, ...
The Journal of clinical investigation 116 (9), 2423-2433, 2006
CD39+ Foxp3+ regulatory T Cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis
JM Fletcher, R Lonergan, L Costelloe, K Kinsella, B Moran, C O'Farrelly, ...
The Journal of Immunology 183 (11), 7602-7610, 2009
Caspase-1–processed cytokines IL-1β and IL-18 promote IL-17 production by γδ and CD4 T cells that mediate autoimmunity
SJ Lalor, LS Dungan, CE Sutton, SA Basdeo, JM Fletcher, KHG Mills
The Journal of Immunology 186 (10), 5738-5748, 2011
Cytomegalovirus-specific CD4+ T cells in healthy carriers are continuously driven to replicative exhaustion
JM Fletcher, M Vukmanovic-Stejic, PJ Dunne, KE Birch, JE Cook, ...
The Journal of Immunology 175 (12), 8218-8225, 2005
Antigen‐specific T cell suppression by human CD4+CD25+ regulatory T cells
LS Taams, M Vukmanovic‐Stejic, J Smith, PJ Dunne, JM Fletcher, ...
European journal of immunology 32 (6), 1621-1630, 2002
Memory T cell homeostasis and senescence during aging
AN Akbar, JM Fletcher
Current opinion in immunology 17 (5), 480-485, 2005
Cytomegalovirus-infected endothelial cells recruit neutrophils by the secretion of CXC chemokines and transmit virus by direct neutrophil-endothelial cell contact and during …
JE Grundy, KM Lawson, LP MacCormac, JM Fletcher, KL Yong
Journal of Infectious Diseases 177 (6), 1465-1474, 1998
The loss of telomerase activity in highly differentiated CD8+ CD28− CD27− T cells is associated with decreased Akt (Ser473) phosphorylation
FJ Plunkett, O Franzese, HM Finney, JM Fletcher, LL Belaramani, ...
The Journal of Immunology 178 (12), 7710-7719, 2007
Hepatitis C virus-specific Th17 cells are suppressed by virus-induced TGF-β
AG Rowan, JM Fletcher, EJ Ryan, B Moran, JE Hegarty, C O'Farrelly, ...
The Journal of Immunology 181 (7), 4485-4494, 2008
Epstein-Barr virus–specific CD8+ T cells that re-express CD45RA are apoptosis-resistant memory cells that retain replicative potential
PJ Dunne, JM Faint, NH Gudgeon, JM Fletcher, FJ Plunkett, MVD Soares, ...
Blood, The Journal of the American Society of Hematology 100 (3), 933-940, 2002
IL-27 mediates the response to IFN-β therapy in multiple sclerosis patients by inhibiting Th17 cells
CM Sweeney, R Lonergan, SA Basdeo, K Kinsella, LS Dungan, ...
Brain, behavior, and immunity 25 (6), 1170-1181, 2011
Attenuating regulatory T cell induction by TLR agonists through inhibition of p38 MAPK signaling in dendritic cells enhances their efficacy as vaccine adjuvants and cancer …
AG Jarnicki, H Conroy, C Brereton, G Donnelly, D Toomey, K Walsh, ...
The Journal of Immunology 180 (6), 3797-3806, 2008
Hidradenitis suppurativa is characterized by dysregulation of the Th17: Treg cell axis, which is corrected by anti-TNF therapy
B Moran, CM Sweeney, R Hughes, A Malara, S Kirthi, AM Tobin, B Kirby, ...
Journal of Investigative Dermatology 137 (11), 2389-2395, 2017
Differential regulation of human Treg and Th17 cells by fatty acid synthesis and glycolysis
D Cluxton, A Petrasca, B Moran, JM Fletcher
Frontiers in immunology 10, 115, 2019
Ex-Th17 (nonclassical Th1) cells are functionally distinct from classical Th1 and Th17 cells and are not constrained by regulatory T cells
SA Basdeo, D Cluxton, J Sulaimani, B Moran, M Canavan, C Orr, ...
The Journal of Immunology 198 (6), 2249-2259, 2017
Telomere erosion in memory T cells induced by telomerase inhibition at the site of antigenic challenge in vivo
JR Reed, M Vukmanovic-Stejic, JM Fletcher, MVD Soares, JE Cook, ...
The Journal of experimental medicine 199 (10), 1433-1443, 2004
Natural killer cell lysis of cytomegalovirus (CMV)-infected cells correlates with virally induced changes in cell surface lymphocyte function-associated antigen-3 (LFA-3 …
JM Fletcher, HG Prentice, JE Grundy
The Journal of Immunology 161 (5), 2365-2374, 1998
CD141+ myeloid dendritic cells are enriched in healthy human liver
A Kelly, R Fahey, JM Fletcher, C Keogh, AG Carroll, R Siddachari, ...
Journal of hepatology 60 (1), 135-142, 2014
The pathogenesis of Parkinson's disease: a complex interplay between astrocytes, microglia, and T lymphocytes?
AN MacMahon Copas, SF McComish, JM Fletcher, MA Caldwell
Frontiers in Neurology 12, 666737, 2021
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Články 1–20