Creating small transcription activating RNAs J Chappell, MK Takahashi, JB Lucks Nature chemical biology 11 (3), 214-220, 2015 | 261 | 2015 |
Validation of an entirely in vitro approach for rapid prototyping of DNA regulatory elements for synthetic biology J Chappell, K Jensen, PS Freemont Nucleic acids research 41 (5), 3471-3481, 2013 | 199 | 2013 |
Rapidly characterizing the fast dynamics of RNA genetic circuitry with cell-free transcription–translation (TX-TL) systems MK Takahashi, J Chappell, CA Hayes, ZZ Sun, J Kim, V Singhal, ... ACS synthetic biology 4 (5), 503-515, 2015 | 175 | 2015 |
A renaissance in RNA synthetic biology: new mechanisms, applications and tools for the future J Chappell, KE Watters, MK Takahashi, JB Lucks Current opinion in chemical biology 28, 47-56, 2015 | 171 | 2015 |
Computational design of small transcription activating RNAs for versatile and dynamic gene regulation J Chappell, A Westbrook, M Verosloff, JB Lucks Nature communications 8 (1), 1051, 2017 | 164 | 2017 |
A Cell-Free Biosensor for Detecting Quorum Sensing Molecules in P. aeruginosa-Infected Respiratory Samples KY Wen, L Cameron, J Chappell, K Jensen, DJ Bell, R Kelwick, ... ACS synthetic biology 6 (12), 2293-2301, 2017 | 155 | 2017 |
Characterizing and prototyping genetic networks with cell-free transcription–translation reactions MK Takahashi, CA Hayes, J Chappell, ZZ Sun, RM Murray, V Noireaux, ... Methods 86, 60-72, 2015 | 141 | 2015 |
Opportunities for microfluidic technologies in synthetic biology S Gulati, V Rouilly, X Niu, J Chappell, RI Kitney, JB Edel, PS Freemont, ... Journal of The Royal Society Interface 6 (suppl_4), S493-S506, 2009 | 115 | 2009 |
The centrality of RNA for engineering gene expression J Chappell, MK Takahashi, S Meyer, D Loughrey, KE Watters, J Lucks Biotechnology journal 8 (12), 1379-1395, 2013 | 90 | 2013 |
Improving fold activation of small transcription activating RNAs (STARs) with rational RNA engineering strategies S Meyer, J Chappell, S Sankar, R Chew, JB Lucks Biotechnology and bioengineering 113 (1), 216-225, 2016 | 56 | 2016 |
Distinct timescales of RNA regulators enable the construction of a genetic pulse generator EF Alexandra Westbrook, Xun Tang, Ryan Marshall, Colin S Maxwell, James ... Biotechnology and bioengineering, 2019 | 51 | 2019 |
PLANT-Dx: a molecular diagnostic for point-of-use detection of plant pathogens M Verosloff, J Chappell, KL Perry, JR Thompson, JB Lucks ACS Synthetic Biology 8 (4), 902-905, 2019 | 46 | 2019 |
A synthetic system for asymmetric cell division in Escherichia coli S Molinari, DL Shis, SP Bhakta, J Chappell, OA Igoshin, MR Bennett Nature chemical biology 15 (9), 917-924, 2019 | 29 | 2019 |
Rational engineering of a modular bacterial CRISPR–Cas activation platform with expanded target range MC Villegas Kcam, AJ Tsong, J Chappell Nucleic Acids Research 49 (8), 4793-4802, 2021 | 23 | 2021 |
Activating natural product synthesis using CRISPR interference and activation systems in Streptomyces A Ameruoso, MC Villegas Kcam, KP Cohen, J Chappell Nucleic Acids Research 50 (13), 7751-7760, 2022 | 19 | 2022 |
Brave new ‘RNA’world—advances in RNA tools and their application for understanding and engineering biological systems A Ameruoso, L Gambill, B Liu, MCV Kcam, J Chappell Current Opinion in Systems Biology 14, 32-40, 2019 | 17 | 2019 |
A split ribozyme that links detection of a native RNA to orthogonal protein outputs L Gambill, A Staubus, KW Mo, A Ameruoso, J Chappell Nature Communications 14 (1), 543, 2023 | 16 | 2023 |
RNA compensation: a positive feedback insulation strategy for RNA-based transcription networks B Liu, C Cuba Samaniego, M Bennett, J Chappell, E Franco ACS Synthetic Biology 11 (3), 1240-1250, 2022 | 7 | 2022 |
Synthetic biology—A new generation of biofilm biosensors J Chappell28 The Science and Applications of Synthetic and Systems Biology: Workshop …, 2011 | 7 | 2011 |
Uncovering the distinct properties of a bacterial type IE CRISPR activation system MC Villegas Kcam, AJ Tsong, J Chappell ACS Synthetic Biology 11 (2), 1000-1003, 2022 | 4 | 2022 |