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Graham Heap
Graham Heap
Royal Devon & Exeter NHS Trust, University of Exeter
Verified email at exeter.ac.uk
Title
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Cited by
Year
Multiple common variants for celiac disease influencing immune gene expression
PCA Dubois, G Trynka, L Franke, KA Hunt, J Romanos, A Curtotti, ...
Nature genetics 42 (4), 295-302, 2010
12062010
Multiple common variants for celiac disease influencing immune gene expression
PCA Dubois, G Trynka, L Franke, KA Hunt, J Romanos, A Curtotti, ...
Nature genetics 42 (4), 295-302, 2010
12062010
Multiple common variants for celiac disease influencing immune gene expression
PCA Dubois, G Trynka, L Franke, KA Hunt, J Romanos, A Curtotti, ...
Nature genetics 42 (4), 295-302, 2010
12062010
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease
KM De Lange, L Moutsianas, JC Lee, CA Lamb, Y Luo, NA Kennedy, ...
Nature genetics 49 (2), 256-261, 2017
11962017
Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease
G Trynka, KA Hunt, NA Bockett, J Romanos, V Mistry, A Szperl, SF Bakker, ...
Nature genetics 43 (12), 1193-1201, 2011
9352011
Shared and distinct genetic variants in type 1 diabetes and celiac disease
DJ Smyth, V Plagnol, NM Walker, JD Cooper, K Downes, JHM Yang, ...
New England Journal of Medicine 359 (26), 2767-2777, 2008
9282008
Newly identified genetic risk variants for celiac disease related to the immune response
KA Hunt, A Zhernakova, G Turner, GAR Heap, L Franke, M Bruinenberg, ...
Nature genetics 40 (4), 395-402, 2008
8432008
Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study
NA Kennedy, GA Heap, HD Green, B Hamilton, C Bewshea, GJ Walker, ...
The lancet Gastroenterology & hepatology 4 (5), 341-353, 2019
5602019
The pattern and outcome of acute severe colitis
LC Dinesen, AJ Walsh, MN Protic, G Heap, F Cummings, BF Warren, ...
Journal of Crohn's and Colitis 4 (4), 431-437, 2010
3762010
HLA-DQA1* 05 carriage associated with development of anti-drug antibodies to infliximab and adalimumab in patients with Crohn’s disease
A Sazonovs, NA Kennedy, L Moutsianas, GA Heap, DL Rice, M Reppell, ...
Gastroenterology 158 (1), 189-199, 2020
3062020
Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-κB signalling
G Trynka, A Zhernakova, J Romanos, L Franke, KA Hunt, G Turner, ...
Gut 58 (8), 1078-1083, 2009
2432009
Genome-wide analysis of allelic expression imbalance in human primary cells by high-throughput transcriptome resequencing
GA Heap, JHM Yang, K Downes, BC Healy, KA Hunt, N Bockett, L Franke, ...
Human molecular genetics 19 (1), 122-134, 2010
2242010
HLA-DQA1–HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants
GA Heap, MN Weedon, CM Bewshea, A Singh, M Chen, JB Satchwell, ...
Nature genetics 46 (10), 1131-1134, 2014
2102014
Association of genetic variants in NUDT15 with thiopurine-induced myelosuppression in patients with inflammatory bowel disease
GJ Walker, JW Harrison, GA Heap, MD Voskuil, V Andersen, ...
Jama 321 (8), 773-785, 2019
1352019
Exclusive enteral nutrition provides an effective bridge to safer interval elective surgery for adults with Crohn's disease
N Heerasing, B Thompson, P Hendy, GA Heap, G Walker, R Bethune, ...
Alimentary pharmacology & therapeutics 45 (5), 660-669, 2017
1262017
Complex nature of SNP genotype effects on gene expression in primary human leucocytes
GA Heap, G Trynka, RC Jansen, M Bruinenberg, MA Swertz, LC Dinesen, ...
BMC medical genomics 2, 1-13, 2009
1152009
Clinical features and HLA association of 5-aminosalicylate (5-ASA)-induced nephrotoxicity in inflammatory bowel disease
GA Heap, K So, M Weedon, N Edney, C Bewshea, A Singh, V Annese, ...
Journal of Crohn's and Colitis 10 (2), 149-158, 2016
1132016
Genetics and pathogenesis of coeliac disease
GA Heap, DA van Heel
Seminars in immunology 21 (6), 346-354, 2009
1132009
Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population
MA Rivas, BE Avila, J Koskela, H Huang, C Stevens, M Pirinen, ...
PLoS genetics 14 (5), e1007329, 2018
922018
The genetics of chronic inflammatory diseases
GA Heap, DA van Heel
Human molecular genetics 18 (R1), R101-R106, 2009
762009
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