Amidines as potent nucleophilic organocatalysts for the transfer of electrophilic bromine from N-bromosuccinimide to alkenes SM Ahmad, DC Braddock, G Cansell, SA Hermitage, JM Redmond, ... Tetrahedron letters 48 (34), 5948-5952, 2007 | 61 | 2007 |
Speciation Control During Suzuki–Miyaura Cross‐Coupling of Haloaryl and Haloalkenyl MIDA Boronic Esters JWB Fyfe, E Valverde, CP Seath, AR Kennedy, JM Redmond, ... Chemistry–A European Journal 21 (24), 8951-8964, 2015 | 60 | 2015 |
Synthesis of functionalised 4 H-quinolizin-4-ones via tandem Horner–Wadsworth–Emmons olefination/cyclisation CW Muir, AR Kennedy, JM Redmond, AJB Watson Organic & biomolecular chemistry 11 (20), 3337-3340, 2013 | 51 | 2013 |
Hi-JAK-ing the ubiquitin system: the design and physicochemical optimisation of JAK PROTACs RR Shah, JM Redmond, A Mihut, M Menon, JP Evans, JA Murphy, ... Bioorganic & Medicinal Chemistry 28 (5), 115326, 2020 | 48 | 2020 |
Tetrahydroisoquinolines affect the whole-cell phenotype of Mycobacterium tuberculosis by inhibiting the ATP-dependent MurE ligase JD Guzman, T Pesnot, DA Barrera, HM Davies, E McMahon, ... Journal of Antimicrobial Chemotherapy 70 (6), 1691-1703, 2015 | 31 | 2015 |
A Convenient Preparation of Enantiomerically Pure (+)‐(1R,2R)‐ and (−)‐(1S,2S)‐1,2‐Diamino‐1,2‐diphenylethanes DC Braddock, JM Redmond, SA Hermitage, AJP White Advanced Synthesis & Catalysis 348 (7‐8), 911-916, 2006 | 29 | 2006 |
Suzuki–Miyaura Coupling Reactions of Iodo (difluoroenol) Derivatives, Fluorinated Building Blocks Accessible at Near-Ambient Temperatures PG Wilson, JM Percy, JM Redmond, AW McCarter The Journal of Organic Chemistry 77 (15), 6384-6393, 2012 | 28 | 2012 |
The generation and trapping of enantiopure bromonium ions DC Braddock, SA Hermitage, L Kwok, R Pouwer, JM Redmond, ... Chemical communications, 1082-1084, 2009 | 24 | 2009 |
Fractional crystallisation of (±)-iso-amarine with mandelic acid: convenient access to (R, R)-and (S, S)-1, 2-diamino-1, 2-diphenylethanes DC Braddock, SA Hermitage, JM Redmond, AJP White Tetrahedron: Asymmetry 17 (20), 2935-2937, 2006 | 17 | 2006 |
Discovery of 3-oxabicyclo [4.1. 0] heptane, a non-nitrogen containing morpholine isostere, and its application in novel inhibitors of the PI3K-AKT-mTOR pathway H Hobbs, G Bravi, I Campbell, M Convery, H Davies, G Inglis, S Pal, ... Journal of medicinal chemistry 62 (15), 6972-6984, 2019 | 16 | 2019 |
The reaction of aromatic dialdehydes with enantiopure 1, 2-diamines: an expeditious route to enantiopure tricyclic amidines DC Braddock, T Cailleau, G Cansell, SA Hermitage, RH Pouwer, ... Tetrahedron: Asymmetry 21 (24), 2911-2919, 2010 | 16 | 2010 |
Compounds αv β6 integrin antagonists NA Anderson, MHJ Campbell-crawford, AP Hancock, JM Pritchard, ... US Patent 9,956,209, 2018 | 12 | 2018 |
Modular Construction of Fluoroarenes from a New Difluorinated Building Block by Cross‐Coupling/Electrocyclisation/Dehydrofluorination Reactions JM Percy, H Emerson, JWB Fyfe, AR Kennedy, S Maciuk, D Orr, ... Chemistry–A European Journal 22 (34), 12166-12175, 2016 | 10 | 2016 |
One-pot near-ambient temperature syntheses of aryl (difluoroenol) derivatives from trifluoroethanol SH Kyne, JM Percy, RDC Pullin, JM Redmond, PG Wilson Organic & Biomolecular Chemistry 9 (24), 8328-8339, 2011 | 10 | 2011 |
A cancer-associated, genome protective programme engaging PKCε PJ Parker, N Lockwood, K Davis, JR Kelly, TN Soliman, AL Pardo, ... Advances in Biological Regulation 78, 100759, 2020 | 8 | 2020 |
A one-pot sonogashira coupling and annulation reaction: An efficient route toward 4H-quinolizin-4-ones Z Chen, T Liu, X Ma, P Liang, L Long, M Ye Synlett 30 (07), 863-867, 2019 | 6 | 2019 |
Design, Synthesis, and Evaluation of Lung-Retentive Prodrugs for Extending the Lung Tissue Retention of Inhaled Drugs J Ayre, JM Redmond, G Vitulli, L Tomlinson, R Weaver, E Comeo, ... Journal of medicinal chemistry 65 (14), 9802-9818, 2022 | 3 | 2022 |
Novel compounds NA ANDERSON, MHJ CAMPBELL-CRAWFORD, AP Hancock, ... | 3 | 2016 |
Naphthyridine derivatives as alpha v beta 6 integrin antagonists for the treatment of EG fibrotic diseases NA Anderson, IB Campbell, MHJ Campbell-crawford, AP Hancock, ... US Patent 10,144,733, 2018 | 2 | 2018 |
Compounds αvβ6 integrin antagonists NA Anderson, MHJ Campbell-crawford, AP Hancock, JM Pritchard, ... US Patent 10,000,489, 2018 | 2 | 2018 |