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Dietary cholesterol drives fatty liver-associated liver cancer by modulating gut microbiota and metabolites X Zhang, OO Coker, ESH Chu, K Fu, HCH Lau, YX Wang, AWH Chan, ... Gut 70 (4), 761-774, 2021 | 449 | 2021 |
Animal models of non‐alcoholic fatty liver disease: current perspectives and recent advances JKC Lau, X Zhang, J Yu The Journal of pathology 241 (1), 36-44, 2017 | 371 | 2017 |
Peptostreptococcus anaerobius induces intracellular cholesterol biosynthesis in colon cells to induce proliferation and causes dysplasia in mice H Tsoi, ESH Chu, X Zhang, J Sheng, G Nakatsu, SC Ng, AWH Chan, ... Gastroenterology 152 (6), 1419-1433. e5, 2017 | 333 | 2017 |
CXCL10 plays a key role as an inflammatory mediator and a non-invasive biomarker of non-alcoholic steatohepatitis X Zhang, J Shen, K Man, ESH Chu, TO Yau, JCY Sung, MYY Go, J Deng, ... Journal of hepatology 61 (6), 1365-1375, 2014 | 207 | 2014 |
Obesity, insulin resistance, NASH and hepatocellular carcinoma J Yu, J Shen, TT Sun, X Zhang, N Wong Seminars in cancer biology 23 (6), 483-491, 2013 | 179 | 2013 |
CXC chemokine receptor 3 promotes steatohepatitis in mice through mediating inflammatory cytokines, macrophages and autophagy X Zhang, J Han, K Man, X Li, J Du, ESH Chu, MYY Go, JJY Sung, J Yu Journal of hepatology 64 (1), 160-170, 2016 | 147 | 2016 |
Discovery of biclonal origin and a novel oncogene SLC12A5 in colon cancer by single-cell sequencing C Yu, J Yu, X Yao, WKK Wu, Y Lu, S Tang, X Li, L Bao, X Li, Y Hou, R Wu, ... Cell research 24 (6), 701-712, 2014 | 143 | 2014 |
Macrophage p38α promotes nutritional steatohepatitis through M1 polarization X Zhang, L Fan, J Wu, H Xu, WY Leung, K Fu, J Wu, K Liu, K Man, X Yang, ... Journal of hepatology 71 (1), 163-174, 2019 | 131 | 2019 |
O-GlcNAc transferase promotes fatty liver-associated liver cancer through inducing palmitic acid and activating endoplasmic reticulum stress W Xu, X Zhang, J Wu, L Fu, K Liu, D Liu, GG Chen, P Bo-san Lai, N Wong, ... Journal of hepatology 67 (2), 310-320, 2017 | 118 | 2017 |
CLDN3 inhibits cancer aggressiveness via Wnt-EMT signaling and is a potential prognostic biomarker for hepatocellular carcinoma L Jiang, YD Yang, L Fu, W Xu, D Liu, Q Liang, X Zhang, L Xu, XY Guan, ... Oncotarget 5 (17), 7663, 2014 | 97 | 2014 |
Targeting the vasculature in hepatocellular carcinoma treatment: Starving versus normalizing blood supply K Liu, X Zhang, W Xu, J Chen, J Yu, JR Gamble, GW McCaughan Clinical and translational gastroenterology 8 (6), e98, 2017 | 89 | 2017 |
Microbial community heterogeneity within colorectal neoplasia and its correlation with colorectal carcinogenesis W Liu, X Zhang, H Xu, S Li, HCH Lau, Q Chen, B Zhang, L Zhao, H Chen, ... Gastroenterology 160 (7), 2395-2408, 2021 | 83 | 2021 |
Significant positive association of endotoxemia with histological severity in 237 patients with non‐alcoholic fatty liver disease J Pang, W Xu, X Zhang, GLH Wong, AWH Chan, HY Chan, CH Tse, ... Alimentary pharmacology & therapeutics 46 (2), 175-182, 2017 | 83 | 2017 |
Defective lysosomal clearance of autophagosomes and its clinical implications in nonalcoholic steatohepatitis X Wang, X Zhang, ESH Chu, X Chen, W Kang, F Wu, KF To, VWS Wong, ... The FASEB Journal 32 (1), 37-51, 2018 | 70 | 2018 |
Squalene epoxidase drives cancer cell proliferation and promotes gut dysbiosis to accelerate colorectal carcinogenesis C Li, Y Wang, D Liu, CC Wong, OO Coker, X Zhang, C Liu, Y Zhou, Y Liu, ... Gut 71 (11), 2253-2265, 2022 | 63 | 2022 |
Pro-inflammatory CXCR3 impairs mitochondrial function in experimental non-alcoholic steatohepatitis J Du, X Zhang, J Han, K Man, Y Zhang, ESH Chu, Y Nan, J Yu Theranostics 7 (17), 4192, 2017 | 60 | 2017 |
Integrative metabolomic characterisation identifies altered portal vein serum metabolome contributing to human hepatocellular carcinoma J Liu, W Geng, H Sun, C Liu, F Huang, J Cao, L Xia, H Zhao, J Zhai, Q Li, ... Gut 71 (6), 1203-1213, 2022 | 55 | 2022 |
The role of gut–liver axis in gut microbiome dysbiosis associated NAFLD and NAFLD-HCC Q Song, X Zhang Biomedicines 10 (3), 524, 2022 | 51 | 2022 |
The phytochemical polydatin ameliorates non‐alcoholic steatohepatitis by restoring lysosomal function and autophagic flux X Chen, H Chan, L Zhang, X Liu, IHT Ho, X Zhang, J Ho, W Hu, Y Tian, ... Journal of Cellular and Molecular Medicine 23 (6), 4290-4300, 2019 | 48 | 2019 |