Guy Perkins
Guy Perkins
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Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane
T Kuwana, MR Mackey, G Perkins, MH Ellisman, M Latterich, R Schneiter, ...
Cell 111 (3), 331-342, 2002
Mitochondrial fragmentation in neurodegeneration
AB Knott, G Perkins, R Schwarzenbacher, E Bossy-Wetzel
Nature Reviews Neuroscience 9 (7), 505-518, 2008
NF-κB restricts inflammasome activation via elimination of damaged mitochondria
Z Zhong, A Umemura, E Sanchez-Lopez, S Liang, S Shalapour, J Wong, ...
Cell 164 (5), 896-910, 2016
Nitric oxide‐induced mitochondrial fission is regulated by dynamin‐related GTPases in neurons
MJ Barsoum, H Yuan, AA Gerencser, G Liot, Y Kushnareva, S Gräber, ...
The EMBO journal 25 (16), 3900-3911, 2006
Disruption of mitochondrial function during apoptosis is mediated by caspase cleavage of the p75 subunit of complex I of the electron transport chain
JE Ricci, C Muñoz-Pinedo, P Fitzgerald, B Bailly-Maitre, GA Perkins, ...
Cell 117 (6), 773-786, 2004
Sestrin as a feedback inhibitor of TOR that prevents age-related pathologies
JH Lee, AV Budanov, EJ Park, R Birse, TE Kim, GA Perkins, K Ocorr, ...
Science 327 (5970), 1223-1228, 2010
Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity
W Song, J Chen, A Petrilli, G Liot, E Klinglmayr, Y Zhou, P Poquiz, J Tjong, ...
Nature medicine 17 (3), 377-382, 2011
Electron tomography of neuronal mitochondria: three-dimensional structure and organization of cristae and membrane contacts
G Perkins, C Renken, ME Martone, SJ Young, M Ellisman, T Frey
Journal of structural biology 119 (3), 260-272, 1997
Crosstalk between nitric oxide and zinc pathways to neuronal cell death involving mitochondrial dysfunction and p38-activated K+ channels
E Bossy-Wetzel, MV Talantova, WD Lee, MN Schölzke, A Harrop, ...
Neuron 41 (3), 351-365, 2004
The pro-apoptotic proteins, Bid and Bax, cause a limited permeabilization of the mitochondrial outer membrane that is enhanced by cytosol
RM Kluck, MD Esposti, G Perkins, C Renken, T Kuwana, E Bossy-Wetzel, ...
The Journal of cell biology 147 (4), 809-822, 1999
ChChd3, an inner mitochondrial membrane protein, is essential for maintaining crista integrity and mitochondrial function
M Darshi, VL Mendiola, MR Mackey, AN Murphy, A Koller, GA Perkins, ...
Journal of biological chemistry 286 (4), 2918-2932, 2011
Preservation of Mitochondrial Structure and Function after Bid- or Bax-Mediated Cytochrome c Release
O von Ahsen, C Renken, G Perkins, RM Kluck, E Bossy-Wetzel, ...
The Journal of cell biology 150 (5), 1027-1036, 2000
Three-dimensional analysis of a viral RNA replication complex reveals a virus-induced mini-organelle
BG Kopek, G Perkins, DJ Miller, MH Ellisman, P Ahlquist
PLoS biology 5 (9), e220, 2007
Covalently linked Au nanoparticles to a viral vector: potential for combined photothermal and gene cancer therapy
M Everts, V Saini, JL Leddon, RJ Kok, M Stoff-Khalili, MA Preuss, ...
Nano letters 6 (4), 587-591, 2006
Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization
R Yamaguchi, L Lartigue, G Perkins, RT Scott, A Dixit, Y Kushnareva, ...
Molecular cell 31 (4), 557-569, 2008
Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3
JH Lee, AV Budanov, S Talukdar, EJ Park, HL Park, HW Park, ...
Cell metabolism 16 (3), 311-321, 2012
Correlated three-dimensional light and electron microscopy reveals transformation of mitochondria during apoptosis
MG Sun, J Williams, C Munoz-Pinedo, GA Perkins, JM Brown, ...
Nature cell biology 9 (9), 1057-1065, 2007
Insight into mitochondrial structure and function from electron tomography
TG Frey, CW Renken, GA Perkins
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1555 (1-3), 196-203, 2002
Mitochondrial rejuvenation after induced pluripotency
ST Suhr, EA Chang, J Tjong, N Alcasid, GA Perkins, MD Goissis, ...
PloS one 5 (11), e14095, 2010
(–)‐Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle
L Nogueira, I Ramirez‐Sanchez, GA Perkins, A Murphy, PR Taub, ...
The Journal of physiology 589 (18), 4615-4631, 2011
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