Madeline R. Luth, Ph.D.
Madeline R. Luth, Ph.D.
Unknown affiliation
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Cited by
Cited by
Biochar characteristics relate to its utility as an alternative soil inoculum carrier to peat and vermiculite
L Hale, M Luth, D Crowley
Soil Biology and Biochemistry 81, 228-235, 2015
Open-source discovery of chemical leads for next-generation chemoprotective antimalarials
Y Antonova-Koch, S Meister, M Abraham, MR Luth, S Ottilie, AK Lukens, ...
Science 362 (6419), eaat9446, 2018
Evaluation of pinewood biochar as a carrier of bacterial strain Enterobacter cloacae UW5 for soil inoculation
L Hale, M Luth, R Kenney, D Crowley
Applied Soil Ecology 84, 192-199, 2014
Using in Vitro Evolution and Whole Genome Analysis To Discover Next Generation Targets for Antimalarial Drug Discovery
MR Luth, P Gupta, S Ottilie, EA Winzeler
ACS infectious diseases 4 (3), 301-314, 2018
Target Validation and Identification of Novel Boronate Inhibitors of the Plasmodium falciparum Proteasome
SC Xie, DL Gillett, NJ Spillman, C Tsu, MR Luth, S Ottilie, S Duffy, ...
Journal of medicinal chemistry 61 (22), 10053-10066, 2018
Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and synergize with multiple antimalarial …
BH Stokes, E Yoo, JM Murithi, MR Luth, P Afanasyev, PCA da Fonseca, ...
PLoS pathogens 15 (6), e1007722, 2019
CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM)
A Debnath, CM Calvet, G Jennings, W Zhou, A Aksenov, MR Luth, ...
PLoS neglected tropical diseases 11 (12), e0006104, 2017
Evolution of resistance in vitro reveals mechanisms of artemisinin activity in Toxoplasma gondii
A Rosenberg, MR Luth, EA Winzeler, M Behnke, LD Sibley
Proceedings of the National Academy of Sciences 116 (52), 26881-26891, 2019
Chemogenomics identifies acetyl-coenzyme A synthetase as a target for malaria treatment and prevention
RL Summers, CFA Pasaje, JP Pisco, J Striepen, MR Luth, K Kumpornsin, ...
Cell chemical biology 29 (2), 191-201. e8, 2022
In vitro selection predicts malaria parasite resistance to dihydroorotate dehydrogenase inhibitors in a mouse infection model
REK Mandt, MJ Lafuente-Monasterio, T Sakata-Kato, MR Luth, D Segura, ...
Science translational medicine 11 (521), eaav1636, 2019
Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway
GM LaMonte, F Rocamora, DS Marapana, NF Gnädig, S Ottilie, MR Luth, ...
Nature communications 11 (1), 1780, 2020
Probing the Open Global Health Chemical Diversity Library for multistage-active starting points for next-generation antimalarials
M Abraham, K Gagaring, ML Martino, M Vanaerschot, DM Plouffe, J Calla, ...
ACS Infectious Diseases 6 (4), 613-628, 2020
Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy
SC Xie, RD Metcalfe, E Dunn, CJ Morton, SC Huang, T Puhalovich, Y Du, ...
Science 376 (6597), 1074-1079, 2022
Efficacy of post-harvest rinsing and bleach disinfection of E. coli O157: H7 on spinach leaf surfaces
NM Kinsinger, HM Mayton, MR Luth, SL Walker
Food microbiology 62, 212-220, 2017
PfMFR3: A Multidrug-Resistant Modulator in Plasmodium falciparum
F Rocamora, P Gupta, ES Istvan, MR Luth, EF Carpenter, K Kümpornsin, ...
ACS Infectious Diseases 7 (4), 811-825, 2021
The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple Plasmodium kinases and life cycle stages
LB Arendse, JM Murithi, T Qahash, CFA Pasaje, LC Godoy, S Dey, ...
Science Translational Medicine 14 (667), eabo7219, 2022
Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance
MA Tye, NC Payne, C Johansson, K Singh, SA Santos, L Fagbami, A Pant, ...
Nature Communications 13 (1), 4976, 2022
Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target
ES Istvan, F Guerra, M Abraham, KS Huang, F Rocamora, H Zhao, L Xu, ...
Science translational medicine 15 (686), eadc9249, 2023
Adaptive laboratory evolution in S. cerevisiae highlights role of transcription factors in fungal xenobiotic resistance
S Ottilie, MR Luth, E Hellemann, GM Goldgof, E Vigil, P Kumar, ...
Communications Biology 5 (1), 128, 2022
Generation of a mutator parasite to drive resistome discovery in Plasmodium falciparum
K Kümpornsin, T Kochakarn, T Yeo, J Okombo, MR Luth, J Hoshizaki, ...
Nature Communications 14 (1), 3059, 2023
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Articles 1–20