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Rachel Karchin
Rachel Karchin
Professor of Biomedical Engineering, Oncology and Computer Science, Johns Hopkins University
Verified email at jhu.edu - Homepage
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Cited by
Cited by
Year
An integrated genomic analysis of human glioblastoma multiforme
DW Parsons, S Jones, X Zhang, JCH Lin, RJ Leary, P Angenendt, ...
science 321 (5897), 1807-1812, 2008
68212008
Integrated genomic analyses of ovarian carcinoma
Cancer Genome Atlas Research Network
Nature 474 (7353), 609, 2011
67672011
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
S Jones, X Zhang, DW Parsons, JCH Lin, RJ Leary, P Angenendt, ...
science 321 (5897), 1801-1806, 2008
45942008
The genomic landscapes of human breast and colorectal cancers
LD Wood, DW Parsons, S Jones, J Lin, T Sjoblom, RJ Leary, D Shen, ...
Science 318 (5853), 1108-1113, 2007
37422007
Comprehensive characterization of cancer driver genes and mutations
MH Bailey, C Tokheim, E Porta-Pardo, S Sengupta, D Bertrand, ...
Cell 173 (2), 371-385. e18, 2018
21052018
Accumulation of driver and passenger mutations during tumor progression
I Bozic, T Antal, H Ohtsuki, H Carter, D Kim, S Chen, R Karchin, ...
Proceedings of the National Academy of Sciences 107 (43), 18545-18550, 2010
9302010
Evolution of neoantigen landscape during immune checkpoint blockade in non–small cell lung cancer
V Anagnostou, KN Smith, PM Forde, N Niknafs, R Bhattacharya, J White, ...
Cancer discovery 7 (3), 264-276, 2017
8192017
The genetic landscape of the childhood cancer medulloblastoma
DW Parsons, M Li, X Zhang, S Jones, RJ Leary, JCH Lin, SM Boca, ...
science 331 (6016), 435-439, 2011
8072011
Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas
Y Jiao, TM Pawlik, RA Anders, FM Selaru, MM Streppel, DJ Lucas, ...
Nature genetics 45 (12), 1470-1473, 2013
6882013
Defining the disease liability of variants in the cystic fibrosis transmembrane conductance regulator gene
PR Sosnay, KR Siklosi, F Van Goor, K Kaniecki, H Yu, N Sharma, ...
Nature genetics 45 (10), 1160-1167, 2013
6702013
High grade serous ovarian carcinomas originate in the fallopian tube
SI Labidi-Galy, E Papp, D Hallberg, N Niknafs, V Adleff, M Noe, ...
Nature communications 8 (1), 1093, 2017
6632017
Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways
J Wu, Y Jiao, M Dal Molin, A Maitra, RF De Wilde, LD Wood, JR Eshleman, ...
Proceedings of the National Academy of Sciences 108 (52), 21188-21193, 2011
6612011
Cancer-specific high-throughput annotation of somatic mutations: computational prediction of driver missense mutations
H Carter, S Chen, L Isik, S Tyekucheva, VE Velculescu, KW Kinzler, ...
Cancer research 69 (16), 6660-6667, 2009
5422009
MODBASE: a database of annotated comparative protein structure models and associated resources
U Pieper, N Eswar, FP Davis, H Braberg, MS Madhusudhan, A Rossi, ...
Nucleic acids research 34 (suppl_1), D291-D295, 2006
5302006
Identifying Mendelian disease genes with the variant effect scoring tool
H Carter, C Douville, PD Stenson, DN Cooper, R Karchin
BMC genomics 14, 1-16, 2013
5132013
The genomic landscape of response to EGFR blockade in colorectal cancer
A Bertotti, E Papp, S Jones, V Adleff, V Anagnostou, B Lupo, M Sausen, ...
Nature 526 (7572), 263-267, 2015
4552015
A combination of molecular markers and clinical features improve the classification of pancreatic cysts
S Springer, Y Wang, M Dal Molin, DL Masica, Y Jiao, I Kinde, A Blackford, ...
Gastroenterology 149 (6), 1501-1510, 2015
4362015
Classifying G-protein coupled receptors with support vector machines
R Karchin, K Karplus, D Haussler
Bioinformatics 18 (1), 147-159, 2002
3762002
Evaluating the evaluation of cancer driver genes
CJ Tokheim, N Papadopoulos, KW Kinzler, B Vogelstein, R Karchin
Proceedings of the National Academy of Sciences 113 (50), 14330-14335, 2016
3662016
Combining local‐structure, fold‐recognition, and new fold methods for protein structure prediction
K Karplus, R Karchin, J Draper, J Casper, Y Mandel‐Gutfreund, ...
Proteins: Structure, Function, and Bioinformatics 53 (S6), 491-496, 2003
3662003
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