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Synthesis, characterization, inhibition effects, and molecular docking studies as acetylcholinesterase, α-glycosidase, and carbonic anhydrase inhibitors of novel …
N Lolak, S Akocak, C Türkeş, P Taslimi, M Işık, Ş Beydemir, İ Gülçin, ...
Bioorganic chemistry 100, 103897, 2020
1422020
An approach to clarify the effect mechanism of glyphosate on body malformations during embryonic development of zebrafish (Daino rerio)
E Sulukan, M Köktürk, H Ceylan, Ş Beydemir, M Işik, M Atamanalp, ...
Chemosphere 180, 77-85, 2017
1122017
Oxidative stress and mRNA expression of acetylcholinesterase in the leukocytes of ischemic patients
M Işık, Ş Beydemir, A Yılmaz, ME Naldan, HE Aslan, İ Gülçin
Biomedicine & pharmacotherapy 87, 561-567, 2017
922017
Changes in the anti-oxidant system in adult epilepsy patients receiving anti-epileptic drugs
M Işık, Y Demir, M Kırıcı, R Demir, F Şimşek, Ş Beydemir
Archives of physiology and biochemistry 121 (3), 97-102, 2015
892015
Synthesis, characterisation, biological evaluation and in silico studies of sulphonamide Schiff bases
M Durgun, C Türkeş, M Işık, Y Demir, A Saklı, A Kuru, A Güzel, ...
Journal of enzyme inhibition and medicinal chemistry 35 (1), 950-962, 2020
882020
Benzenesulfonamide derivatives as potent acetylcholinesterase, α-glycosidase, and glutathione S-transferase inhibitors: biological evaluation and molecular docking studies
P Taslimi, M Işık, F Türkan, M Durgun, C Türkeş, İ Gülçin, Ş Beydemir
Journal of Biomolecular Structure and Dynamics 39 (15), 5449-5460, 2021
872021
Phenolic compounds inhibit the aldose reductase enzyme from the sheep kidney
Y Demir, M Işık, İ Gülçin, Ş Beydemir
Journal of biochemical and molecular toxicology 31 (9), e21936, 2017
842017
Synthesis, characterization, and inhibition study of novel substituted phenylureido sulfaguanidine derivatives as α‐glycosidase and cholinesterase inhibitors
S Akocak, P Taslimi, N Lolak, M Işık, M Durgun, Y Budak, C Türkeş, ...
Chemistry & biodiversity 18 (4), e2000958, 2021
722021
Synthesis, characterization, biological evaluation, and in silico studies of novel 1, 3‐diaryltriazene‐substituted sulfathiazole derivatives
M Işık, S Akocak, N Lolak, P Taslimi, C Türkeş, İ Gülçin, M Durgun, ...
Archiv Der Pharmazie 353 (9), 2000102, 2020
692020
Molecular docking and investigation of 4-(benzylideneamino)-and 4-(benzylamino)-benzenesulfonamide derivatives as potent AChE inhibitors
M Işık, Y Demir, M Durgun, C Türkeş, A Necip, Ş Beydemir
Chemical Papers 74 (5), 1395-1405, 2020
692020
Novel inhibitors with sulfamethazine backbone: synthesis and biological study of multi-target cholinesterases and α-glucosidase inhibitors
C Türkeş, S Akocak, M Işık, N Lolak, P Taslimi, M Durgun, İ Gülçin, ...
Journal of Biomolecular Structure and Dynamics 40 (19), 8752-8764, 2022
682022
Benzenesulfonamide derivatives containing imine and amine groups: Inhibition on human paraoxonase and molecular docking studies
M Işık, Ş Beydemir, Y Demir, M Durgun, C Türkeş, A Nasır, A Necip, ...
International journal of biological macromolecules 146, 1111-1123, 2020
682020
Determination of antioxidant properties of Gypsophila bitlisensis bark
H Tohma, M Isik, M Korkmaz, E Bursal, I Gulcin, E Koksal
Int J Pharmacol 11 (4), 366-71, 2015
502015
Biological effects of bis-hydrazone compounds bearing isovanillin moiety on the aldose reductase
G Yapar, HE Duran, N Lolak, S Akocak, C Türkeş, M Durgun, M Işık, ...
Bioorganic chemistry 117, 105473, 2021
482021
Mannich reaction derived novel boron complexes with amine-bis (phenolate) ligands: Synthesis, spectroscopy and in vitro/in silico biological studies
A Kilic, L Beyazsakal, M Işık, C Türkeş, A Necip, K Takım, Ş Beydemir
Journal of Organometallic Chemistry 927, 121542, 2020
472020
The binding mechanisms and inhibitory effect of intravenous anesthetics on AChE in vitro and in vivo: kinetic analysis and molecular docking
M Işık
Neurochemical research 44 (9), 2147-2155, 2019
372019
Novel bis-ureido-substituted sulfaguanidines and sulfisoxazoles as carbonic anhydrase and acetylcholinesterase inhibitors
N Lolak, S Akocak, M Durgun, HE Duran, A Necip, C Türkeş, M Işık, ...
Molecular Diversity 27 (4), 1735-1749, 2023
352023
High stability of immobilized acetylcholinesterase on chitosan beads
M Işık
ChemistrySelect 5 (15), 4623-4627, 2020
292020
Phytochemical analysis of Paliurus spina-christi fruit and its effects on oxidative stress and antioxidant enzymes in streptozotocin-induced diabetic rats
K Takım, M Işık
Applied biochemistry and biotechnology 191 (4), 1353-1368, 2020
282020
AChE mRNA expression as a possible novel biomarker for the diagnosis of coronary artery disease and Alzheimer’s disease, and its association with oxidative stress
M Işık, Ş Beydemir
Archives of physiology and biochemistry 128 (2), 352-359, 2022
252022
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Články 1–20